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MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. Additionally we are shipping Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 2 Proteins (5) and many more products for this protein.
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Human Polyclonal KCNMB2 Primary Antibody for WB - ABIN1881476
Zarei, Song, Wilson, Cox, Colom, Knaus, Stefani, Toro: Endocytic trafficking signals in KCNMB2 regulate surface expression of a large conductance voltage and Ca(2+)-activated K+ channel. in Neuroscience 2007
Show all 5 Pubmed References
Mammalian Monoclonal KCNMB2 Primary Antibody for ISt, IHC - ABIN1304557
Zhang, Mok, Lee, Charbonnet, Gold: Inflammation-induced changes in BK(Ca) currents in cutaneous dorsal root ganglion neurons from the adult rat. in Molecular pain 2012
Show all 2 Pubmed References
The study verified that the BK(Ca) channel alpha-subunit (show POLG Antibodies) is located to smooth muscle cells of porcine basilar and middle cerebral arteries.
IFN-gamma (show IFNG Antibodies) changed mRNA levels of the BK beta-modulatory proteins KCNMB2 (increased) and KCNMB4 (show KCNMB4 Antibodies) (decreased) as well as leucine-rich repeat-containing protein (LRRC)26 (show LRRC26 Antibodies) (decreased).
results reveal the molecular regions in the beta1 and beta2 subunits that determine their differential functional coupling with the pore-forming alpha-subunit (show POLG Antibodies)
significance of inactivation in BK channels mediated by beta subunits arises not from inactivation, but from differences in the amplitude and duration of repolarizing currents arising from the beta-subunit (show POLG Antibodies)-specific energetics of recovery from inactivation
reports that coexpression of beta2 subunit (KCNMB2) with hSlo (show KCNMA1 Antibodies) can also modulate hSlo (show KCNMA1 Antibodies) surface expression levels in HEK293T cells
Report beta subunit (show POLG Antibodies) (KNMB1-4)-specific modulations of BK channel (show KCNMA1 Antibodies) function by a Slo1 (show KCNMA1 Antibodies) mutation associated with epilepsy and dyskinesia.
we conclude that colonic K(+) secretion is intact or even increased in mice lacking the beta2-subunit of KCa1.1 (show KCNMA1 Antibodies) channel complex despite no additional compensatory induction of KCa1.1 (show KCNMA1 Antibodies) beta-subunits.
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Two variants encoding the same protein have been found for this gene.
calcium-activated potassium channel beta 2 subunit
, potassium large conductance calcium-activated channel, subfamily M beta member 3
, calcium-activated potassium channel subunit beta-2
, calcium-activated potassium channel subunit beta-3
, potassium large conductance calcium-activated channel, subfamily M, beta member 2
, BK channel subunit beta-2
, MaxiK channel beta 2 subunit
, charybdotoxin receptor subunit beta-2
, large conductance calcium-activated potassium channel beta 2 subunit
, large-conductance Ca2+-activated K+ channel beta2 subunit
, calcium-activated potassium channel, subfamily M subunit beta-2
, maxi K channel subunit beta-2
, calcium-activated potassium channel beta 2