PMEL Proteins
PMEL encodes a melanocyte-specific type I transmembrane glycoprotein.
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Premelanosome Protein (PMEL) (AA 25-434) protein (rho-1D4 tag) Protein
Premelanosome Protein (PMEL) (AA 25-626) protein (rho-1D4 tag) Protein
Premelanosome Protein (PMEL) (AA 437-626) protein (rho-1D4 tag) Protein
Premelanosome Protein (PMEL) (AA 470-595) protein (His tag) Protein
Premelanosome Protein (PMEL) (AA 437-562) protein (His tag) Protein
Premelanosome Protein (PMEL) (AA 470-661) protein (rho-1D4 tag) Protein
Premelanosome Protein (PMEL) (AA 25-467) protein (rho-1D4 tag) Protein
Premelanosome Protein (PMEL) (AA 25-661) protein (rho-1D4 tag) Protein
Premelanosome Protein (PMEL) (AA 1-661) protein (GST tag) Protein
Premelanosome Protein (PMEL) (AA 25-467) protein (His-SUMO Tag) Protein
PMEL Protein Profile
Protein Summary
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
Gene names and symbols associated with Premelanosome Protein Proteins (PMEL)
- premelanosome protein (PMEL) antibody
- premelanosome protein (Pmel) antibody
- premelanosome protein a (pmela) antibody
- cb397 antibody
- D10H12S53E antibody
- D12S53E antibody
- D12S53Eh antibody
- fdv antibody
- gp87 antibody
- gp100 antibody
- ME20 antibody
- ME20-M antibody
- ME20M antibody
- MMP115 antibody
- P1 antibody
- P100 antibody
- pmel17 antibody
- RPE1 antibody
- sb:cb397 antibody
- Si antibody
- SIL antibody
- Silv antibody
- silva antibody
- silver antibody
- wu:fc11g11 antibody
- wu:fj24g11 antibody
- zgc:136622 antibody
Protein level used designations for Premelanosome Protein Proteins (PMEL)
melanocyte protein PMEL , melanocyte protein Pmel 17 , melanocyte protein mel 17 , melanocytes lineage-specific antigen GP100 , melanoma-associated ME20 antigen , melanosomal matrix protein17 , silver locus protein homolog , silver, mouse, homolog of , melanocyte protein pmel 17 , silver locus protein , retinal pigment epithelial-specific protein , silver homolog , 115 kDa melanosomal matrix protein , PMEL17 protein , melanocyte protein 17 , premelanosomal protein , fading vision , melanosomal matrix protein , silver homolog a
| GENE ID | SPECIES |
|---|---|
| 6490 | Homo sapiens |
| 20431 | Mus musculus |
| 281487 | Bos taurus |
| 362818 | Rattus norvegicus |
| 396007 | Gallus gallus |
| 481102 | Canis lupus familiaris |
| 594851 | Sus scrofa |
| 102176102 | Capra hircus |
| 100033885 | Equus caballus |
| 100347477 | Oryctolagus cuniculus |
| 321239 | Danio rerio |
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