Protein Kinase D3 (PRKD3) ELISA Kits

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. Additionally we are shipping Protein Kinase D3 Antibodies (117) and Protein Kinase D3 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PRKD3 PRKD3 23683 O94806
Anti-Mouse PRKD3 PRKD3 75292 Q8K1Y2
Anti-Rat PRKD3 PRKD3 313834  
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More ELISA Kits for Protein Kinase D3 Interaction Partners

Human Protein Kinase D3 (PRKD3) interaction partners

  1. None of the Polymorphous low-grade adenocarcinoma (PLGA) lacking PRKD1 (show PRKD1 ELISA Kits) somatic mutations or PRKD gene family rearrangements harboured somatic mutations in the kinase domains of the PRKD2 (show PKD2 ELISA Kits) or PRKD3 genes.

  2. This study discovered and characterized a novel, highly conserved N-terminal domain, comprising 92 amino acids, which mediates dimerization of Protein Kinase D (PKD) isoforms, PKD1 (show PKD1 ELISA Kits), PKD2 (show PKD2 ELISA Kits), and PKD3 monomers.

  3. Studies indicate that the loss of protein kinase D PKD1 is thought to promote invasion and metastasis, while PKD2 (show PKD2 ELISA Kits) and upregulated PKD3 to be positive regulators of proliferation.

  4. Loss of PKD2 (show PKD2 ELISA Kits) enhanced KC proliferative potential while loss of PKD3 resulted in a progressive proliferation defect, loss of clonogenicity and diminished tissue regenerative ability.

  5. for the first time, PKD3 is implicated in the transcription activation of latent HIV-1 provirus, and our results revealed a molecular mechanism of prostratin-induced HIV-1 transcription via PKCepsilon (show PRKCE ELISA Kits)/PKD3/NF-kappaB (show NFKB1 ELISA Kits) signaling pathway.

  6. Activation of PKD2 (show PKD2 ELISA Kits) and further increase of PKD3 activity leads to additional phosphorylation and inhibition of endogenous phosphatase slingshot 1L (show SSH1 ELISA Kits).

  7. PKD3 in TNBC cells provides a molecular connection between the Golgi and endolysosomal compartments to enhance proliferative mTORC1-S6K1 (show RPS6KB1 ELISA Kits) signaling.

  8. PKD3 negatively regulates human airway epithelial barrier formation and integrity through down-regulation of claudin-1 (show CLDN7 ELISA Kits), which is a key component of tight junctions.

  9. PKD3 may contribute to the malignant progression of prostate cancer cells through negative regulation of MMP-7 (show MMP7 ELISA Kits) expression.

  10. PKD3 contributes to the proliferation and malignant growth of androgen-dependent prostate cancer cells in part by upregulating PSA expression.

Mouse (Murine) Protein Kinase D3 (PRKD3) interaction partners

  1. These data provide new insights of a specific PKD3 signaling pathway by identifying a new function, which has not been identified before.

  2. Erythropoietin (show EPO ELISA Kits) regulates GATA1 (show GATA1 ELISA Kits) through protein kinase D (show PRKD1 ELISA Kits) activation, promoting histone deacetylase 5 (show HDAC5 ELISA Kits) dissociation from GATA1 (show GATA1 ELISA Kits), and subsequent GATA1 (show GATA1 ELISA Kits) acetylation.

  3. These data validate PKD3 as a promising therapeutic target in prostate cancer and shed light on the role of secreted tumor-promoting factors in prostate cancer progression.

  4. PKCnu is an important component of signaling pathways downstream from novel PKC enzymes after B-cell receptor engagement

  5. the catalytic activity of PKD3 may regulate its nuclear import through autophosphorylation and/or interaction with another protein

  6. PKD3 is increasingly expressed in neuronal as well as in the supporting connective tissue and in skeletal muscles

  7. reveal a novel distinction between the exocrine and endocrine cells of the pancreas and further identify PKD3 as a signaling molecule that promotes hormone-stimulated amylase (show AMY ELISA Kits) secretion

Protein Kinase D3 (PRKD3) Antigen Profile

Antigen Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

Gene names and symbols associated with Protein Kinase D3 (PRKD3) ELISA Kits

  • protein kinase D3 (PRKD3) antibody
  • protein kinase D3 (prkd3) antibody
  • protein kinase D3 (Prkd3) antibody
  • 4930557O20Rik antibody
  • 5730497N19Rik antibody
  • EPK2 antibody
  • nPKC-NU antibody
  • PKC-NU antibody
  • Pkcnu antibody
  • PKD3 antibody
  • Prkcn antibody
  • PRKD3 antibody

Protein level used designations for Protein Kinase D3 (PRKD3) ELISA Kits

protein kinase C nu type , protein kinase C, nu , protein kinase EPK2 , protein-serine/threonine kinase , serine/threonine-protein kinase D3 , protein kinase D3 , serine/threonine-protein kinase D3-like , nPKC-nu

23683 Homo sapiens
421478 Gallus gallus
459158 Pan troglodytes
483036 Canis lupus familiaris
538447 Bos taurus
709647 Macaca mulatta
100397078 Callithrix jacchus
100438207 Pongo abelii
100466224 Ailuropoda melanoleuca
100523181 Sus scrofa
100077901 Ornithorhynchus anatinus
100563064 Anolis carolinensis
100581692 Nomascus leucogenys
75292 Mus musculus
313834 Rattus norvegicus
100712662 Cavia porcellus
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