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The protein encoded by PPM1G is a member of the PP2C family of Ser/Thr protein phosphatases. Additionally we are shipping PPM1G Proteins (21) and and many more products for this protein.
Showing 10 out of 119 products:
Human Polyclonal PPM1G Primary Antibody for IHC (p), IP - ABIN258055
Ryan, Khleborodova, Pan, Ryan: Small molecule activators of pre-mRNA 3' cleavage. in RNA (New York, N.Y.) 2009
Show all 2 Pubmed References
Nuclear phosphatase PPM1G in cellular survival and neural development.
PPM1G phosphatase directly binds 7SK RNA and the kinase inhibitor Hexim1 (show HEXIM1 Antibodies) once P-TEFb (show CCNT1 Antibodies) has been released from the 7SK snRNP (show LSM2 Antibodies).
Hypermethylation in the 3'-protein-phosphatase-1G (PPM1G) gene locus was associated with alcohol use disorder.
PPM1G inactivates monomeric WWP2 (show WWP2 Antibodies) and promotes the assembly of WWP2 (show WWP2 Antibodies)-WWP1 (show WWP1 Antibodies) heterodimeric complex.
PPM1G dephosphorylates the P-TEFb (show CCNT1 Antibodies) kinase T loop to disassemble the 7SK snRNP (show LSM2 Antibodies).
study has identified protein phosphatase PPM1G as a novel regulator of cap-dependent protein translation by negatively controlling the phosphorylation of 4E-BP1 (show EIF4EBP1 Antibodies).
ATM (show ATM Antibodies)-dependent downregulation of USP7/HAUSP (show USP7 Antibodies) by PPM1G activates p53 (show TP53 Antibodies) response to DNA damage
The degradation of p21(WAF1/CIP1 (show CDKN1A Antibodies)) induced by PP2Cgamma was mediated in a proteasome-dependent manner.
Protein phosphatase 2C gamma mediates histone dephosphorylation/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes.
PP2Cgamma modulates alternative splicing of specific pre-mRNAs coregulated by YB-1 (show YBX1 Antibodies).
an interplay between PPM1G and unrip (show STRAP Antibodies) determine compartment-specific phosphorylation patterns, localization, and function of the SMN (show STMN1 Antibodies) complex
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
, fibroblast growth factor inducible 13
, fibroblast growth factor-inducible protein 13
, protein phosphatase 1C
, protein phosphatase 1G
, protein phosphatase 2C isoform gamma
, protein phosphatase magnesium-dependent 1 gamma
, PP2C, gamma
, protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
, protein phosphatase 2, catalytic subunit, gamma isoform
, protein phosphatase 2C gamma isoform
, magnesium-dependent calcium inhibitable phosphatase
, protein phosphatase 1B