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The protein encoded by PTP4A1 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. Additionally we are shipping PTP4A1 Proteins (9) and PTP4A1 Kits (1) and many more products for this protein.
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Human Polyclonal PTP4A1 Primary Antibody for ELISA, WB - ABIN185274
Peng, Genin, Spinner, Diamond, Taub: The gene encoding human nuclear protein tyrosine phosphatase, PRL-1. Cloning, chromosomal localization, and identification of an intron enhancer. in The Journal of biological chemistry 1998
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data shed new light on the structural basis underlying the interaction between PRL (show PRL Antibodies) phosphatases and CNNM transporters and provides a hypothesis about the molecular mechanism by which PRL-1, upon binding to CNNM2 (show CNNM2 Antibodies), might increase the intracellular concentration of Mg(2 (show MCOLN1 Antibodies)+) thereby contributing to tumor progression and metastasis.
Prl-1 is required for proper timing of liver regeneration after partial hepatectomy
PRL-1 binding to p115 (show ARHGAP4 Antibodies) RhoGAP (show ARHGAP1 Antibodies) provides a coordinated mechanism underlying ERK1/2 and RhoA (show RHOA Antibodies) activation
In cones and cone-derived cultured cells both Prl-1 activity and Prl-1 gene expression are modulated under oxidative stress.
PTP4A1 is highly expressed in fibroblasts from patients with systemic sclerosis and enhances pro-fibrotic TGFbeta (show TGFB1 Antibodies) signaling in these cells.
PTP4A1 was overexpressed in ICC and played an important role in the progression and metastasis of ICC. The functional role of PTP4A1 was assumed to be acted by activation PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling and promoting the EMT (show ITK Antibodies) process through two pivotal transcriptional factors Zeb1 (show ZEB1 Antibodies) and Snail (show SNAI1 Antibodies).
Results showed that SIAH1 (show SIAH1 Antibodies) and PTP4A1 expression was regulated by mir (show MLXIP Antibodies)-944 in breast cancer cells. miR (show MLXIP Antibodies)-944 binds directly the 3 UTR (show UTS2R Antibodies) of their promotor region.
miR (show MLXIP Antibodies)-601 inhibits growth and invasion of breast cancer cells by targeting PTP4A1.
Data indicate that protein-tyrosine-phosphatase of regenerating liver 1 (PRL1) gene was expressed much more highly in prostate cancer (PCa (show FLVCR1 Antibodies)) than in nonneoplastic prostate samples.
Upregulation of PRL-1 (show PLRG1 Antibodies) expression is inversely correlated with miR (show MLXIP Antibodies)-26a in primary cervical cancer tissues.
Data highlight the oncogenic function of PRL-1 (show PLRG1 Antibodies) in HCC (show FAM126A Antibodies) invasion and metastasis.
We confirmed with our previous findings that PTP4A1-PHF3-EYS (show EYS Antibodies) variants were significantly associated with alcohol dependence.
PTP4A1-PHF3-EYS (show EYS Antibodies) variants were associated with alcohol dependence.
Results suggest that TRP32 (show TXNL1 Antibodies) maintains the reduced state of PRL (show PRL Antibodies) and thus regulates the biological function of PRL (show PRL Antibodies).
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.
protein tyrosine phosphatase type IVA 1
, protein tyrosine phosphatase type IVA, member 1
, Protein tyrosine phosphatase type IVA 1
, protein-tyrosine phosphatase 4a1
, protein-tyrosine phosphatase of regenerating liver 1
, protein tyrosine phosphatase type IVA protein 1
, protein tyrosine phosphatase 4a1