anti-Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1) Antibodies

The protein encoded by PTP4A1 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. Additionally we are shipping PTP4A1 Proteins (10) and PTP4A1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTP4A1 19243 Q63739
PTP4A1 7803 Q93096
PTP4A1 29463 Q78EG7
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Top anti-PTP4A1 Antibodies at antibodies-online.com

Showing 10 out of 102 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN263147 (1µg/ml) staining of A549 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Chicken Goat Un-conjugated ELISA 100 μg Log in to see 11 to 14 Days
$610.50
Details
Chicken Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$610.50
Details
Human Rabbit Un-conjugated WB PTP4A1 Antibody (C-term)  western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the PTP4A1 antibody detected the PTP4A1 protein (arrow). Western blot analysis of PTP4A1 (arrow) using rabbit polyclonal PTP4A1 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PTP4A1 gene. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of PRL1 (ABIN392856) in mouse spleen tissue lysates (35 µg/lane). PRL1 Antibody (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, WB ABIN6273302 at 1/100 staining Human lymph tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of MCF7 cells, using PTP4A1/PRL1 antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Goat Un-conjugated EIA, WB   0.1 mg Log in to see 8 to 11 Days
$462.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of PTP4A1 expression in transfected 293T cell line by PTP4A1 MaxPab polyclonal antibody.Lane 1: PTP4A1 transfected lysate(19.03 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using PTP4A1 antibody (ABIN5998630) at 1:3000 dilution. 100 μL Log in to see 11 to 18 Days
$412.19
Details

Top referenced anti-PTP4A1 Antibodies

  1. Human Polyclonal PTP4A1 Primary Antibody for ELISA - ABIN545047 : Wang, Kirby, Herbst: The tyrosine phosphatase PRL-1 localizes to the endoplasmic reticulum and the mitotic spindle and is required for normal mitosis. in The Journal of biological chemistry 2002 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal PTP4A1 Primary Antibody for ELISA, WB - ABIN185274 : Peng, Genin, Spinner, Diamond, Taub: The gene encoding human nuclear protein tyrosine phosphatase, PRL-1. Cloning, chromosomal localization, and identification of an intron enhancer. in The Journal of biological chemistry 1998 (PubMed)
    Show all 3 Pubmed References

More Antibodies against PTP4A1 Interaction Partners

Human Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1) interaction partners

  1. PTP4A1 is a direct downstream target of miR-1271 in the hepatocellular carcinoma.

  2. PTP4A1 is highly expressed in fibroblasts from patients with systemic sclerosis and enhances pro-fibrotic TGFbeta signaling in these cells.

  3. PTP4A1 was overexpressed in ICC and played an important role in the progression and metastasis of ICC. The functional role of PTP4A1 was assumed to be acted by activation PI3K/AKT signaling and promoting the EMT process through two pivotal transcriptional factors Zeb1 and Snail.

  4. Results showed that SIAH1 and PTP4A1 expression was regulated by mir-944 in breast cancer cells. miR-944 binds directly the 3 UTR of their promotor region.

  5. miR-601 inhibits growth and invasion of breast cancer cells by targeting PTP4A1.

  6. Data indicate that protein-tyrosine-phosphatase of regenerating liver 1 (PRL1) gene was expressed much more highly in prostate cancer (PCa) than in nonneoplastic prostate samples.

  7. Upregulation of PRL-1 expression is inversely correlated with miR-26a in primary cervical cancer tissues.

  8. Data highlight the oncogenic function of PRL-1 in HCC invasion and metastasis.

  9. We confirmed with our previous findings that PTP4A1-PHF3-EYS variants were significantly associated with alcohol dependence.

  10. PTP4A1-PHF3-EYS variants were associated with alcohol dependence.

  11. Results suggest that TRP32 maintains the reduced state of PRL and thus regulates the biological function of PRL.

  12. Studies indicate that PRL-1 and PRL-2 and PRL-3 are oncogenes and belong to the few phosphatases that lead to the development of cancer.

  13. upregulation of PRL-1 protein correlates with shortened patient survival in human hepatocellular carcinoma

  14. Data conclude that the PHF3-PTP4A1 region appears to harbor a causal locus for alcohol dependence, and proteins encoded by PHF3 and/or PTP4A1 might play a functional role in the disorder.

  15. PRL-1 binding to p115 RhoGAP provides a coordinated mechanism underlying ERK1/2 and RhoA activation

  16. Increased PRL1 expression results in activation of Src and ERK1/2, which stimulates MMP2 and MMP9 production, leading to increased cell migration and invasion.

  17. PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics

  18. PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase

  19. PRL-1 phosphatase has a trimeric structure which reveals an active enzyme conformation and regulation mechanisms

  20. PRL-1 mRNA expression was not significantly higher in malignant compared to benign breast tissue.

PTP4A1 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.

Gene names and symbols associated with PTP4A1

  • protein tyrosine phosphatase type IVA, member 1 (PTP4A1) antibody
  • protein tyrosine phosphatase type IVA, member 1 L homeolog (ptp4a1.L) antibody
  • protein tyrosine phosphatase type IVA, member 1 (ptp4a1) antibody
  • protein tyrosine phosphatase type IVA, member 1 (Ptp4a1) antibody
  • protein tyrosine phosphatase 4a1 (Ptp4a1) antibody
  • AA415290 antibody
  • AU019864 antibody
  • C130021B01 antibody
  • DKFZp459E022 antibody
  • fb54d08 antibody
  • fc01c04 antibody
  • HH72 antibody
  • MGC79517 antibody
  • MGC83351 antibody
  • Prl-1 antibody
  • PRL1 antibody
  • PTP(CAAX1) antibody
  • PTP4A1 antibody
  • PTPCAAX1 antibody
  • wu:fb54d08 antibody
  • wu:fc01c04 antibody
  • zgc:101726 antibody

Protein level used designations for PTP4A1

protein tyrosine phosphatase type IVA 1 , protein tyrosine phosphatase type IVA, member 1 , PRL-1 , Protein tyrosine phosphatase type IVA 1 , protein-tyrosine phosphatase 4a1 , protein-tyrosine phosphatase of regenerating liver 1 , protein tyrosine phosphatase type IVA protein 1 , protein tyrosine phosphatase 4a1

GENE ID SPECIES
421877 Gallus gallus
446679 Xenopus laevis
472046 Pan troglodytes
481863 Canis lupus familiaris
493385 Xenopus (Silurana) tropicalis
493615 Danio rerio
100163237 Acyrthosiphon pisum
100173305 Pongo abelii
19243 Mus musculus
7803 Homo sapiens
29463 Rattus norvegicus
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