Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1) ELISA Kits

The protein encoded by PTP4A1 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. Additionally we are shipping PTP4A1 Antibodies (104) and PTP4A1 Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PTP4A1 PTP4A1 19243 Q63739
PTP4A1 7803 Q93096
Anti-Rat PTP4A1 PTP4A1 29463 Q78EG7
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Top PTP4A1 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details

More ELISA Kits for PTP4A1 Interaction Partners

Mouse (Murine) Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1) interaction partners

  1. data shed new light on the structural basis underlying the interaction between PRL phosphatases and CNNM transporters and provides a hypothesis about the molecular mechanism by which PRL-1, upon binding to CNNM2, might increase the intracellular concentration of Mg(2+) thereby contributing to tumor progression and metastasis.

  2. Prl-1 is required for proper timing of liver regeneration after partial hepatectomy

  3. PRL-1 binding to p115 RhoGAP provides a coordinated mechanism underlying ERK1/2 and RhoA activation

  4. In cones and cone-derived cultured cells both Prl-1 activity and Prl-1 gene expression are modulated under oxidative stress.

Human Protein Tyrosine Phosphatase Type IVA, Member 1 (PTP4A1) interaction partners

  1. Overexpression of miR-339-5p enhanced radiosensitivity of A549 and H460 cells by inhibiting cell viability, increasing apoptosis, inducing cell cycle arrest, and suppressing cell proliferation. Further exploration validated that miR-339-5p can target phosphatases of regenerating liver-1 (PRL-1) in lung cancer cells.

  2. PRL mRNA transcription was stimulated by Mg(2+) depletion. A series of analyses revealed the activation and the crucial importance of signal transducer and activator of transcription 1 in this process. Collectively, these results implicate PRL in maintaining cellular Mg(2+) homeostasis.

  3. PTP4A1 is a direct downstream target of miR-1271 in the hepatocellular carcinoma.

  4. PTP4A1 is highly expressed in fibroblasts from patients with systemic sclerosis and enhances pro-fibrotic TGFbeta signaling in these cells.

  5. PTP4A1 was overexpressed in ICC and played an important role in the progression and metastasis of ICC. The functional role of PTP4A1 was assumed to be acted by activation PI3K/AKT signaling and promoting the EMT process through two pivotal transcriptional factors Zeb1 and Snail.

  6. Results showed that SIAH1 and PTP4A1 expression was regulated by mir-944 in breast cancer cells. miR-944 binds directly the 3 UTR of their promotor region.

  7. miR-601 inhibits growth and invasion of breast cancer cells by targeting PTP4A1.

  8. Data indicate that protein-tyrosine-phosphatase of regenerating liver 1 (PRL1) gene was expressed much more highly in prostate cancer (PCa) than in nonneoplastic prostate samples.

  9. Upregulation of PRL-1 expression is inversely correlated with miR-26a in primary cervical cancer tissues.

  10. Data highlight the oncogenic function of PRL-1 in HCC invasion and metastasis.

  11. We confirmed with our previous findings that PTP4A1-PHF3-EYS variants were significantly associated with alcohol dependence.

  12. PTP4A1-PHF3-EYS variants were associated with alcohol dependence.

  13. Results suggest that TRP32 maintains the reduced state of PRL and thus regulates the biological function of PRL.

  14. Studies indicate that PRL-1 and PRL-2 and PRL-3 are oncogenes and belong to the few phosphatases that lead to the development of cancer.

  15. upregulation of PRL-1 protein correlates with shortened patient survival in human hepatocellular carcinoma

  16. Data conclude that the PHF3-PTP4A1 region appears to harbor a causal locus for alcohol dependence, and proteins encoded by PHF3 and/or PTP4A1 might play a functional role in the disorder.

  17. PRL-1 binding to p115 RhoGAP provides a coordinated mechanism underlying ERK1/2 and RhoA activation

  18. Increased PRL1 expression results in activation of Src and ERK1/2, which stimulates MMP2 and MMP9 production, leading to increased cell migration and invasion.

  19. PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics

  20. PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase

PTP4A1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.

Gene names and symbols associated with PTP4A1

  • protein tyrosine phosphatase type IVA, member 1 (PTP4A1) antibody
  • protein tyrosine phosphatase type IVA, member 1 L homeolog (ptp4a1.L) antibody
  • protein tyrosine phosphatase type IVA, member 1 (ptp4a1) antibody
  • protein tyrosine phosphatase type IVA, member 1 (Ptp4a1) antibody
  • protein tyrosine phosphatase 4a1 (Ptp4a1) antibody
  • AA415290 antibody
  • AU019864 antibody
  • C130021B01 antibody
  • DKFZp459E022 antibody
  • fb54d08 antibody
  • fc01c04 antibody
  • HH72 antibody
  • MGC79517 antibody
  • MGC83351 antibody
  • Prl-1 antibody
  • PRL1 antibody
  • PTP(CAAX1) antibody
  • PTP4A1 antibody
  • PTPCAAX1 antibody
  • wu:fb54d08 antibody
  • wu:fc01c04 antibody
  • zgc:101726 antibody

Protein level used designations for PTP4A1

protein tyrosine phosphatase type IVA 1 , protein tyrosine phosphatase type IVA, member 1 , PRL-1 , Protein tyrosine phosphatase type IVA 1 , protein-tyrosine phosphatase 4a1 , protein-tyrosine phosphatase of regenerating liver 1 , protein tyrosine phosphatase type IVA protein 1 , protein tyrosine phosphatase 4a1

GENE ID SPECIES
421877 Gallus gallus
446679 Xenopus laevis
472046 Pan troglodytes
481863 Canis lupus familiaris
493385 Xenopus (Silurana) tropicalis
493615 Danio rerio
100163237 Acyrthosiphon pisum
100173305 Pongo abelii
19243 Mus musculus
7803 Homo sapiens
29463 Rattus norvegicus
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