anti-Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) Antibodies

The protein encoded by PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). Additionally we are shipping PTP4A3 Proteins (11) and PTP4A3 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTP4A3 11156 O75365
PTP4A3 19245 Q9D658
PTP4A3 362930  
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Top anti-PTP4A3 Antibodies at antibodies-online.com

Showing 10 out of 76 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PTP4A3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PTP4A3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>ACHN cell lysate WB Suggested Anti-PTP4A3 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of PTP4A3 C-term (ABIN392855) in MCF-7 and 293 cell line lysates (35 µg/lane). PTP4A3 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB ABIN257782 staining (2µg/ml) of Human Pancreas lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Western Blot: PRL-3/PTP4A3 Antibody [ABIN257782] - (0.03ug/ml) of Human Pancreas lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB The monoclonal antibody anti-PRL3 (ABIN387832) is used in Western blot to detect PRL3 in 293 cells transfected with PRL3. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of PRL3 Antibody (ABIN392854) in mouse heart tissue lysates (35 µg/lane). PRL3 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
$368.50
Details

PTP4A3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-PTP4A3 Antibodies

  1. Human Polyclonal PTP4A3 Primary Antibody for ELISA, WB - ABIN257782 : Fagerli, Holt, Holien, Vaatsveen, Zhan, Egeberg, Barlogie, Waage, Aarset, Dai, Shaughnessy, Sundan, Børset: Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells. in Blood 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal PTP4A3 Primary Antibody for ELISA, WB - ABIN564844 : Fromont, Godet, Peyret, Irani, Celhay, Rozet, Cathelineau, Cussenot: 8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy. in Human pathology 2013 (PubMed)

More Antibodies against PTP4A3 Interaction Partners

Human Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) interaction partners

  1. We conclude that PRL-3 is an important regulatory factor for breast cancer cell proliferation and invasion. Loss of PRL-3 function induces an antimetastatic gene expression profile in breast cancer cells. Due to its role in tumor growth and metastasis, PRL-3 emerges as a new therapeutic target in breast cancer therapy.

  2. Since high PRL-3 expression also correlates with poor prognosis in other cancers and functional studies in PC support these findings, PRL-3 emerges as a potential treatment target in PC

  3. Data show that phosphatase of regenerating liver-3 (PRL (show PRL Antibodies)-3a) is an important mediator of growth factor signaling in MM cells and hence possibly a good target for treatment of MM.

  4. Data suggest that phosphatase of regenerating liver-3 (PRL-3)might play a tumor suppressor role in lung cancer, distinct from other cancers, by inhibiting epithelial-mesenchymal transition (EMT (show ITK Antibodies))-related pathways.

  5. A novel role of PRL-3 in tumor development through its adverse impact on telomere homeostasis.

  6. our result indicated that PRL-3 promotes protein phosphorylation by acting as an 'activator kinase' and consequently regulates cytokine secretion.

  7. The disruption of epithelial architecture by PRL-3 revealed here is a newly recognized mechanism for PRL-3-promoted cancer progression.

  8. This study suggests PRL-3 and SFKs are key mediators of the IL6 (show IL6 Antibodies)-driven signaling events.

  9. Regulation of PTP4A3 expression is altered in specific subgroups of acute leukemias and this is likely brought about by expression of the aberrant ETV6 (show ETV6 Antibodies)-RUNX1 (show RUNX1 Antibodies) and BCR (show BCR Antibodies)-ABL1 (show ABL1 Antibodies) fusion genes.

  10. PRL-3 engages the focal adhesion pathway in trip0le-negative breast cancer cells as a key mechanism for promoting TNBC cell migration and invasion.

Zebrafish Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) interaction partners

  1. Results uncovered that aberrant overexpression of PRL-3 could initiate chordoma in early development.

Xenopus laevis Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) interaction partners

  1. Data show that protein-tyrosine phosphatase (show ACP1 Antibodies) PRP4A3 (prl3) and van gogh like1 (vangl1 (show Vangl1 Antibodies)) are Necessary Components in prohibitin1 (phb1 (show PHB Antibodies)) dependent neural crest specification.

  2. PTP4A3 is required for cephalic neural crest migration in vivo during embryonic development.

Mouse (Murine) Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) interaction partners

  1. our results suggest that the Prl3b1-cre mice line provides a unique resource to understand testicular germ-cell development

  2. Results demonstrate that Ptp4a3 contributes to the malignant phenotype of tumor-initiating cells.

  3. PRL-3 protein was significantly reduced in mouse STAT3 (show STAT3 Antibodies)-knockout liver cells compared with STAT3 (show STAT3 Antibodies)-wild type counterparts, and ectopic expression of STAT3 (show STAT3 Antibodies) in these cells led to a pronounced increase in PRL-3 protein.

  4. Data indicate that Mycobacterium tuberculosis T cell stimulatory epitope (MT) is a potentially effective molecular adjuvant in preparation of monoclonal antibody (mAb) specific for phosphatase of regenerating liver-3 (PRL-3).

  5. These findings strongly support a role for PTP4A3 as an important contributor to endothelial cell function and as a multimodal target for cancer therapy and mitigating VEGF (show VEGFA Antibodies)-regulated angiogenesis.

  6. the first definitive evidence implicating Ptp4a3 in colon tumorigenesis

  7. role of PTP4A3 in acute myeloid leukemia (show BCL11A Antibodies)

  8. PTP4A3 was identified as a novel negative regulator of LPS (show TLR4 Antibodies)-induced LITAF/TNF-alpha production.

  9. PRL-3 was highly expressed in metastatic melanoma B16-BL6 cells but not in its lowly metastatic parental cell line, B16 cells

  10. PRL-3-expressing cells rapidly induce metastatic tumor formation in lung

PTP4A3 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.

Gene names and symbols associated with PTP4A3

  • protein tyrosine phosphatase type IVA, member 3 (PTP4A3) antibody
  • protein tyrosine phosphatase type IVA, member 3 (ptp4a3) antibody
  • protein tyrosine phosphatase type IVA, member 3 L homeolog (ptp4a3.L) antibody
  • protein tyrosine phosphatase 4a3 (Ptp4a3) antibody
  • protein tyrosine phosphatase type IVA, member 3 (Ptp4a3) antibody
  • AV088979 antibody
  • pPtp4a3 antibody
  • Prl-3 antibody
  • PRL-R antibody
  • prl3 antibody
  • PTP4A3 antibody
  • ptpcaax3 antibody
  • wu:fc54b05 antibody
  • wu:fv52d11 antibody
  • zgc:77109 antibody

Protein level used designations for PTP4A3

potentially prenylated protein tyrosine phosphatase , protein tyrosine phosphatase type IVA 3 , protein-tyrosine phosphatase 4a3 , protein-tyrosine phosphatase of regenerating liver 3 , PRL-3 , fc54b05 , fv52d11 , xPRL-3 , protein tyrosine phosphatase type IVA, member 3 , protein tyrosine phosphatase 4a3

GENE ID SPECIES
11156 Homo sapiens
406460 Danio rerio
432351 Xenopus laevis
606961 Canis lupus familiaris
737820 Pan troglodytes
768713 Gallus gallus
100137722 Bos taurus
100216017 Xenopus (Silurana) tropicalis
100342107 Oryctolagus cuniculus
19245 Mus musculus
362930 Rattus norvegicus
100724863 Cavia porcellus
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