Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) Proteins (PTPN18)

The protein encoded by PTPN18 is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping PTPN18 Antibodies (31) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTPN18 26469 Q99952
PTPN18 19253 Q61152
Rat PTPN18 PTPN18 301333  
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Top PTPN18 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

PTPN18 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18) Interaction Partners

Human Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18) interaction partners

  1. PTPN12, PTPRN and PTPN18 were independent prognostic factors in Hepatocellular Carcinoma.

  2. PTPN18 regulates HER2 (show ERBB2 Proteins)-mediated cellular functions through defining both its phosphorylation and ubiquitination barcodes.

  3. BDP1 has a role in negative regulation of HER2 (show ERBB2 Proteins) signaling

  4. novel isoform of PTPN18 based on analysis of expressed sequence tags was discovered; deletion of 4 exons in the catalytic domain of the isoform may alter enzymatic activity; 2 of the novel isoform predictions were experimentally validated through RT-PCR

Mouse (Murine) Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18) interaction partners

  1. BDP1 has a role in negative regulation of HER2 (show ERBB2 Proteins) signaling

PTPN18 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PTPN18

  • protein tyrosine phosphatase, non-receptor type 18 (PTPN18)
  • protein tyrosine phosphatase, non-receptor type 18 (Ptpn18)
  • BDP1 protein
  • FLP1 protein
  • HSCF protein
  • PTP-HSCF protein
  • PTP-K1 protein
  • PTP20 protein
  • Ptpk1 protein

Protein level used designations for PTPN18

brain-derived phosphatase , tyrosine-protein phosphatase non-receptor type 18 , FLP-1 , fetal liver phosphatase 1 , protein tyrosine phosphatase 20

GENE ID SPECIES
26469 Homo sapiens
19253 Mus musculus
301333 Rattus norvegicus
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