Protocadherin gamma A3 ELISA Kits

PCDHgA3 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five.

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1 Product
Pre-coated, Samples: Serum, Plasma, Tissue Homogenate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range62.5-4000 pg/mL
Order details Cat. No. ABIN820069
$910.56
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
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Protocadherin gamma A3 (PCDHgA3) Antigen Profile

Protein Summary

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Gene names and symbols associated with PCDHgA3

  • protocadherin gamma subfamily A, 3 (PCDHGA3) antibody
  • protocadherin gamma subfamily A, 3 (Pcdhga3) antibody
  • PCDH-GAMMA-A3 antibody

Protein level used designations for PCDHgA3

protocadherin gamma-A3 , PCDH-gamma-A3

GENE ID SPECIES
56112 Homo sapiens
93711 Mus musculus
498847 Rattus norvegicus
738470 Pan troglodytes
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