anti-RAB1A, Member RAS Oncogene Family (RAB1A) Antibodies

RAB1A encodes a member of the Ras superfamily of GTPases.

list all antibodies Gene Name GeneID UniProt
Anti-Human RAB1A RAB1A 5861 P62820
Anti-Mouse RAB1A RAB1A 19324 P62821
Anti-Rat RAB1A RAB1A 81754 Q6NYB7
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Top anti-RAB1A Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-RAB1A Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Muscle <b>Sample Type:</b> 1. Human Cervical Cancer Cell Lysate (15ug)<br>2. Monkey Fibroblast Cell Lysate (15ug)<br>3. Human Cervical Cancer Cell transfected with Rab1A-GFP (15ug)<br><b>Primary Dilution:</b> 1:1000<br><b>Secondary Antibody</b>: goat anti-Rabbit<br><b>Secondary Dilution:</b> 1:40,000<br><b>Image Submitted by:</b> Dr. Jakob Szwedo, Dr. Lupashin's Lab<br>University of Arkansas for Medical Sciences.<br><br> 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Image Western Blot analysis of RAB1A expression in transfected 293T cell line by RAB1A polyclonal antibody. A: Non-transfected lysate. B: RAB1A transfected lysate. 12% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 1 to 2 Days
$292.60
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Used in DAB staining on fromalin fixed paraffin- embedded kidney tissue 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Goat Un-conjugated IF, IHC, IHC (p), WB   300 μg Log in to see 7 to 9 Days
$484.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.63 KDa) . 200 μL Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB RAB1A antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$473.93
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry: Rab1A Antibody [NBP1-55113] - Formalin Fixed Paraffin Embedded Tissue: Human Bronchial Epithelial Tissue Observed Staining: Cytoplasmic in excellent staining Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec Western Blot: Rab1A Antibody [NBP1-55113] - Analysis of HepG2 cell lysate. Antibody Dilution: 1.0 ug/ml. 100 μL Log in to see 8 to 11 Days
$556.31
Details
Human Mouse Un-conjugated ELISA, WB   200 μL Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Un-conjugated IHC, ELISA   100 μL Log in to see 7 to 9 Days
$390.50
Details

Top referenced anti-RAB1A Antibodies

  1. Human Monoclonal RAB1A Primary Antibody for ELISA, WB - ABIN519577 : Thomas, Zhang, Wei, Cho, Morris, Wang, Zheng: Rab1A is an mTORC1 activator and a colorectal oncogene. in Cancer cell 2014 (PubMed)

  2. Human Polyclonal RAB1A Primary Antibody for IF, WB - ABIN1440053 : Mojallal, Zheng, Hultin, Audebert, van Harn, Johnsson, Lenander, Fritz, Mieth, Corcoran, Lembo, Hallström, Hartman, Mazure, Weide, Grandér, Borg, Uhlén, Holmgren: AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion. in Nature communications 2014 (PubMed)

More Antibodies against RAB1A Interaction Partners

Human RAB1A, Member RAS Oncogene Family (RAB1A) interaction partners

  1. Rab1 is regulated by the host in a similar fashion, and that the innate immunity kinase TAK1 (show MAP3K7 Antibodies) and Legionella effectors compete to regulate Rab1 by switch II modifications during infection.

  2. Rab1A may be involved in the pathogenesis of human lung cancer in an mTOR (show FRAP1 Antibodies)- and MAPK (show MAPK1 Antibodies)-independent manner.

  3. In clinical samples, the expression of Rab1A or DHX33 (show DHX33 Antibodies) was reversely correlated with miR (show MLXIP Antibodies)-634. Re-expression of Rab1A or DHX33 (show DHX33 Antibodies) abrogated the miR (show MLXIP Antibodies)-634-mediated inhibition of cell proliferation and migration. Collectively, our data suggest a tumor suppressor role of miR (show MLXIP Antibodies)-634 in hepatocellular carcinoma.

  4. New Rab1 binding sites have been discovered using an ensemble of clustering methods.

  5. Leucine-rich repeat kinase 2 (LRRK2) can interact with several Rab proteins, and such ractions may serve to recruit LRRK2 to distinct subcellular organelles to phosphorylate select substrate proteins involved in membrane trafficking events.

  6. As a Rab1a effector, C9orf72 (show C9ORF72 Antibodies) controls initiation of autophagy by regulating the Rab1a-dependent trafficking of the ULK1 (show ULK1 Antibodies) autophagy initiation complex to the phagophore.

  7. our data indicate that miR (show MLXIP Antibodies)-1202 suppresses proliferation and induces endoplasmic reticulum stress and apoptosis through targeting and inhibiting Rab1A in glioma cells. These results suggest miR (show MLXIP Antibodies)-1202 as a potential therapeutic target for the treatment of glioma patients.

  8. Upregulation of RAB1A is associated with triple-negative breast cancer.

  9. For RAB1A, a high accuracy for the discrimination of human hepatocellular carcinoma and nontumorous liver tissue was observed.

  10. The ability of Rab1 to regulate WHAMM and the Arp2/3 complex represents a distinct strategy for membrane remodeling in which a Rab G-protein recruits the actin nucleation machinery but dampens its activity.

Zebrafish RAB1A, Member RAS Oncogene Family (RAB1A) interaction partners

  1. The authors demonstrate in zebrafish that nf1 (show NF1 Antibodies) loss leads to aberrant activation of RAS signaling in MYCN (show MYCN Antibodies)-induced neuroblastomas that arise in these precursors, and that the GTPase-activating protein (GAP)-related domain (GRD) is sufficient to suppress the acceleration of neuroblastoma (show ARHGEF16 Antibodies) in nf1 (show NF1 Antibodies)-deficient fish, but not the hypertrophy of sympathoadrenal cells in nf1 (show NF1 Antibodies) mutant embryos.

  2. Ras activity levels control the repopulation and expansion of adult melanocyte precursors after tissue loss, enabling the recovery of patterned melanocyte stripes during zebrafish appendage regeneration.

Pig (Porcine) RAB1A, Member RAS Oncogene Family (RAB1A) interaction partners

Fruit Fly (Drosophila melanogaster) RAB1A, Member RAS Oncogene Family (RAB1A) interaction partners

  1. It has been demonstrated that the COG (show TG Antibodies) complex cooperates with Rab1 and GOLPH3 (show GOLPH3 Antibodies) to regulate Golgi trafficking, and that overexpression of Rab1 can rescue the cytokinesis and locomotor defects associated with loss of Cog7 (show COG7 Antibodies).

  2. Drosophila Tempura, a novel protein prenyltransferase alpha subunit, regulates notch signaling via Rab1 and Rab11.

  3. Results suggest a novel function for Rab1a in the regulation of cell migration through controlling integrin beta1 recycling and localization to lipid rafts via a specific downstream effector pathway.

Mouse (Murine) RAB1A, Member RAS Oncogene Family (RAB1A) interaction partners

  1. clear effect of subcutaneous zoledronic acid administration in vivo on the prenylation of Rab1A, Rab5B (show RAB5B Antibodies), Rab7A (show RAB7A Antibodies) and Rab14 (show RAB14 Antibodies) in mouse peritoneal macrophages, confirming that systemic treatment with bisphosphonate drug can inhibit prenylation in myeloid cells in vivo outside the skeleton.

  2. Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP

  3. These data indicate that AMPylation of Rab1 is an effective strategy to maintain this GTPase (show RACGAP1 Antibodies) on the Legionella-containing vacuole membrane.

  4. Rab1A is the first crucial component of the anterograde melanosome transport machinery to be identified in mammalian skin melanocytes.

  5. Acute expression of Rab1 and Rab3d (show RAB3D Antibodies) DN constructs partially alleviated this negative feedback mechanism and resulted in impaired ER to Golgi trafficking of procollagen.

  6. Legionella pneumophila SidD catalyzed AMP (show TMPRSS5 Antibodies) release from Rab1, generating de-AMPylated Rab1 accessible for inactivation by LepB; identified SidD as missing link connecting processes of early Rab1 accumulation and subsequent removal during infection

  7. Results suggest a novel function for Rab1a in the regulation of cell migration through controlling integrin beta1 recycling and localization to lipid rafts via a specific downstream effector pathway.

  8. Rab1 and Rab6 GTPases may play a role in modulating the function of retina by mediating the transport of nascent proteins along the early secretary pathway, particularly in the process of the light adaptation.

  9. Data show Trs130 (show TRAPPC9 Antibodies) (mTrs130) is a component of an analogous TRAPP complex that this complex is enriched on COPI (Coat Protein (show GOLPH3 Antibodies) I (show ANXA2 Antibodies))-coated vesicles it specifically activates Rab1.

  10. elevated expression of Rab1 protected against alpha-Synuclein-induced dopaminergic neuron loss in animal models of Parkinson Disease

RAB1A Antigen Profile

Protein Summary

This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms.

Gene names and symbols associated with RAB1A

  • RAB1A, member RAS oncogene family (RAB1A) antibody
  • RAB1A, member RAS oncogene family b (rab1ab) antibody
  • RAB1A, member RAS oncogene family L homeolog (rab1a.L) antibody
  • RAB1B, member RAS oncogene family (RAB1B) antibody
  • RAB1A, member RAS oncogene family (rab1a) antibody
  • CG3320 gene product from transcript CG3320-RA (Rab1) antibody
  • rab1A protein (rab1A) antibody
  • PfRab1a (Rab1a) antibody
  • hypothetical protein (Rab1a) antibody
  • Rab GTPase (rab1A) antibody
  • angiogenin (ANG) antibody
  • RAB1A, member RAS oncogene family (Rab1a) antibody
  • AAF55873 antibody
  • Ac2-048 antibody
  • CG3320 antibody
  • dar6 antibody
  • DDBDRAFT_0185730 antibody
  • DDBDRAFT_0191476 antibody
  • DDB_0185730 antibody
  • DDB_0191476 antibody
  • Dmel\\CG3320 antibody
  • DmRab1 antibody
  • Dm Rab1 antibody
  • drab1 antibody
  • fb53a02 antibody
  • Gtbp antibody
  • MGC53138 antibody
  • mKIAA3012 antibody
  • oncogene antibody
  • Rab-1 antibody
  • Rab1 antibody
  • Rab1A antibody
  • RAB1B antibody
  • Rab1r antibody
  • RAS antibody
  • si:zc101n13.3 antibody
  • wu:fb53a02 antibody
  • Ypt1 antibody

Protein level used designations for RAB1A

GTP binding protein Rab1a , RAB1, member RAS oncogene family , Rab GTPase YPT1 homolog , YPT1-related protein , ras-related protein Rab-1A , RAB1A, member RAS oncogene family , RAB1B, member RAS oncogene family , Rab-protein 1 , CG3320-PA , Rab1-PA , dendritic arbor reduction 6 , rab1A protein , PfRab1a , hypothetical protein , RNase 5 , angiogenin , ribonuclease 5 , ras-related YPT1 protein

GENE ID SPECIES
5861 Homo sapiens
368883 Danio rerio
379830 Xenopus laevis
403774 Canis lupus familiaris
421273 Gallus gallus
448007 Xenopus (Silurana) tropicalis
459280 Pan troglodytes
539339 Bos taurus
595116 Sus scrofa
696962 Macaca mulatta
100196294 Salmo salar
100302065 Ovis aries
100339709 Oryctolagus cuniculus
42524 Drosophila melanogaster
553886 Lotus japonicus
812953 Plasmodium falciparum 3D7
7195044 Phaeodactylum tricornutum CCAP 1055/1
8624312 Dictyostelium discoideum AX4
100034041 Equus caballus
19324 Mus musculus
81754 Rattus norvegicus
101087312 Felis catus
100860796 Capra hircus
100719957 Cavia porcellus
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