RAD18 Homolog (S. Cerevisiae) (RAD18) ELISA Kits

The protein encoded by RAD18 is highly similar to S.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RAD18 RAD18 56852 Q9NS91
Anti-Mouse RAD18 RAD18 58186 Q9QXK2
Anti-Rat RAD18 RAD18 362412  
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Top RAD18 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 4.7 pg/mL 18.75-1200 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details

More ELISA Kits for RAD18 Interaction Partners

Human RAD18 Homolog (S. Cerevisiae) (RAD18) interaction partners

  1. Data suggest that, as part of DNA repair in nucleus of embryonic stem cells, IGF1R interacts with and phosphorylates PCNA at tyrosine residues 60, 133, and 250; this is followed by mono- and polyubiquitination of PCNA by RAD18 and SHPRH. (IGF1R = insulin-like growth factor 1 receptor; PCNA = proliferating cell nuclear antigen; RAD18 = E3 ubiquitin-protein ligase RAD18; SHPRH = E3 ubiquitin-protein ligase SHPRH)

  2. Ubiquitin ligases RNF168, RNF169, and RAD18 specifically bind histone H2A Lys13/15-ubiquitylated nucleosomes. 53BP1 (show TP53BP1 ELISA Kits) chromatin recruitment may be activated by RNF168 and blocked by RNF169 and RAD18.

  3. WRNIP1 (show WRNIP1 ELISA Kits) connects PCNA (show PCNA ELISA Kits) monoubiquitination with ATMIN/ATM (show ATM ELISA Kits) to activate ATM (show ATM ELISA Kits) signalling in response to replication stress and contribute to the maintenance of genomic stability.

  4. RAD18 polymorphisms are correlated with the side effects of platinum-chemotherapy in Chinese patients with advanced NSCLC.

  5. REV1 can promote (show PCNA ELISA Kits)PCNA monoubiquitylation after UV radiation through interacting with ubiquitylated RAD18.

  6. USP7-mediated de-ubiquitylation protects Rad18 from proteasomal degradation and is necessary for the integrity of the specialized translesion synthesis pathway

  7. RAD18 can function as a mediator for DNA damage response signals to activate the G2/M checkpoint in order to maintain genome integrity and cell survival after IR exposure.

  8. Significantly restored tolerance of RAD18-/- and RNF8-/- cells to camptothecin and olaparib without affecting Rad51 (show RAD51 ELISA Kits) focus formation.

  9. these results suggest that miR (show MLXIP ELISA Kits)-145 can act as an RAD18 inhibitor and contribute as an important factor in reversing drug resistance after chemotherapy.

  10. We obtained a molecular envelope for Rad18 UBZ-ELRM:linear Ub2 polyubiquitin (show UBB ELISA Kits) chains by small-angle X-ray scattering and derived a structural model for the complex.

Mouse (Murine) RAD18 Homolog (S. Cerevisiae) (RAD18) interaction partners

  1. Somatic hypermutation of immunoglobulin genes (SHM (show CNTNAP1 ELISA Kits)) in Rad18 KO mice was similar to wild-type mice, suggesting that Rad18 is dispensable for SHM (show CNTNAP1 ELISA Kits).

  2. Rad18 confers DNA damage tolerance and tumor-suppression in a physiological setting.

  3. REV1 promote PCNA (show PCNA ELISA Kits) monoubiquitylation after UV radiation through interacting with ubiquitylated RAD18.

  4. RAD18 can function as a mediator for DNA damage response signals to activate the G2/M checkpoint in order to maintain genome integrity and cell survival after IR exposure.

  5. RAD18 contributes to maintenance of genomic stability through postreplication repair

  6. Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase

  7. Rad18 suppresses viral infection in a non-specific fashion, probably by targeting incoming DNA.

  8. RAD18 is intrinsically required for the long-term maintenance of spermatogenesis.

RAD18 Antigen Profile

Antigen Summary

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

Gene names and symbols associated with RAD18

  • RAD18, E3 ubiquitin protein ligase (RAD18) antibody
  • RAD18 E3 ubiquitin protein ligase (Rad18) antibody
  • RAD18 E3 ubiquitin protein ligase (rad18) antibody
  • E3 ubiquitin-protein ligase RAD18 (RAD18) antibody
  • E3 ubiquitin-protein ligase (RAD18) antibody
  • DNA repair protein and ATPase (RAD18) antibody
  • C3HC4-type zinc finger-containing protein (rad18) antibody
  • RAD18, E3 ubiquitin protein ligase (Rad18) antibody
  • 2810024C04Rik antibody
  • DDBDRAFT_0218120 antibody
  • DDBDRAFT_0304878 antibody
  • DDB_0218120 antibody
  • DDB_0304878 antibody
  • DKFZp469H0810 antibody
  • RAD18 antibody
  • Rad18sc antibody
  • RNF73 antibody
  • zgc:55577 antibody

Protein level used designations for RAD18

E3 ubiquitin-protein ligase RAD18 , RAD18, S. cerevisiae, homolog , RING finger protein 73 , hHR18 , hRAD18 , postreplication repair protein RAD18 , postreplication repair protein hRAD18p , mRAD18Sc , post-replication repair protein RAD18SC , RAD18 homolog (S. cerevisiae) , similar to postreplication repair protein hRAD18p , E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair , Rad18p , hypothetical protein , DNA repair protein and ATPase , SAP DNA-binding domain-containing protein , RAD18 homolog , RAD18-like protein , E3 ubiquitin-protein ligase RAD18-like , e3 ubiquitin-protein ligase RAD18-like

GENE ID SPECIES
56852 Homo sapiens
58186 Mus musculus
362412 Rattus norvegicus
393106 Danio rerio
416114 Gallus gallus
460144 Pan troglodytes
476544 Canis lupus familiaris
514440 Bos taurus
704708 Macaca mulatta
850430 Saccharomyces cerevisiae S288c
3641637 Candida albicans SC5314
4839641 Scheffersomyces stipitis CBS 6054
8621702 Dictyostelium discoideum AX4
100052645 Equus caballus
100172537 Pongo abelii
100217383 Sus scrofa
100395032 Callithrix jacchus
100473633 Ailuropoda melanoleuca
100591424 Nomascus leucogenys
100720939 Cavia porcellus
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