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RBM3 is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Additionally we are shipping RBM3 Kits (14) and RBM3 Proteins (9) and many more products for this protein.
Showing 10 out of 67 products:
Human Polyclonal RBM3 Primary Antibody for ICC, IF - ABIN4349610
Jögi, Brennan, Rydén, Magnusson, Fernö, Stål, Borgquist, Uhlen, Landberg, Påhlman, Pontén, Jirström: Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer. in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009
Show all 3 Pubmed References
Human Polyclonal RBM3 Primary Antibody for ELISA, WB - ABIN451818
Sureban, Ramalingam, Natarajan, May, Subramaniam, Bishnupuri, Morrison, Dieckgraefe, Brackett, Postier, Houchen, Anant: Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe. in Oncogene 2008
Human Monoclonal RBM3 Primary Antibody for IF, IHC (p) - ABIN519669
Zhang, Zhang, Xue, Kong, Liu, Li, Liu, Xu: Differential expression of the RNA-binding motif protein 3 in human astrocytoma. in Chinese medical journal 2013
Loss of RBM3 expression is an unfavourable prognostic marker in colorectal cancers (CRCs), and is linked to right-sided tumour localization.
High RBM3 expression is an independent predictor of prolonged survival in metastatic colorectal cancer patients.
Results show that RBM3 overexpression results in increased stemness in colon cancer cells, and inactivation of GSK3 through phosphorylation, thereby enhancing b-catenin signaling activity the colorectal cancer cells.
Low RBM3 expression is associated with colon Cancer.
Studies showed RBM3 as one of the important cold shock protein with critical roles in rapid cell adaption to the alterations of the environmental stress. Also, RBM3 plays an important role in neuroprotection, anti-apoptotic functions, cell proliferation as well as its function as proto-oncogene (show RAB1A Antibodies).[review]
The results indicate the existence of a negative feedback loop that regulates fever via reduced RBM3 levels and increased expression of miR (show MLXIP Antibodies)-142-5p and miR (show MLXIP Antibodies)-143.
Low RBM3 immunoexpression is associated with urothelial carcinoma of the bladder.
RBM3 may be a potential biomarker for treatment stratification in patients with metastatic non-seminomatous germ cell tumours.
High RBM3 expression is an independent prognostic marker in prostate cancer.
The data suggest that the overexpression of RBM3 may serve as an important molecular mechanism underlying astrocytic carcinogenesis.
deficient synapse regeneration, mediated at least in part by failure of the RBM3 stress response, contributes to synapse loss throughout the course of neurodegenerative disease
Moderate hypothermia resulted in significant up-regulation of both RBM3 and CIRP (show CIRBP Antibodies) mRNA in murine organotypic hippocampal slice cultures
Up-regulation of neuronal RBM3 apparently accounts for a substantial proportion of hypothermia-induced neuroprotection in the developing postnatal murine brain.
Overexpression of RBM3 in skeletal muscle myoblasts is associated with an increase in cell survival through inhibitory actions on both apoptosis and necrosis.
Rbm3(-/-) mouse embryonic fibroblasts have markedly increased number of G2-phase cells, suggesting a hitherto unknown role of RBM3 in the G2-phase control.
Data suggest that both Rbm3 and microRNAs are part of a homeostatic mechanism that regulates global levels of protein synthesis under normal and cold-stress conditions.
the RNA stabilizing and translation regulatory protein (show TGFB1 Antibodies) RBM3 is a novel proto-oncogene (show RAB1A Antibodies) that induces transformation when overexpressed and is essential for cells to progress through mitosis.
This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria.
RNA-binding motif protein 3
, putative RNA-binding protein 3
, RNA binding motif protein 3