Ras and Rab Interactor 1 (RIN1) ELISA Kits

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Additionally we are shipping RIN1 Antibodies (46) and RIN1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human RIN1 RIN1 9610 Q13671
Anti-Mouse RIN1 RIN1 225870 Q921Q7
Anti-Rat RIN1 RIN1 207119 P97680
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More ELISA Kits for RIN1 Interaction Partners

Human Ras and Rab Interactor 1 (RIN1) interaction partners

  1. Findings suggest that RIN1 plays an important oncogenic role in clear cell renal cell carcinoma malignancy by activation of EGFR (show EGFR ELISA Kits) signaling through interacting with Rab25 (show RAB25 ELISA Kits).

  2. Smad2 (show SMAD2 ELISA Kits) is a key scaffold, allowing RIN1 to act as a GTP (show AK3 ELISA Kits) exchange factor for MFN2 (show MFN2 ELISA Kits)-GTPase (show RACGAP1 ELISA Kits) activation to promote mitochondrial ATP synthesis and suppress superoxide production during mitochondrial fusion.

  3. Overexpression experiments in tandem with pull-down assays indicated that specific Ser291/292 phosphorylation of RIN1 favored binding to activated Ras

  4. analysis of a novel deregulated mechanism in chronic myeloid leukemia (show BCL11A ELISA Kits) patients, indicating BIN1 (show BIN1 ELISA Kits) and RIN1 as players in the maintenance of the abnormal RTK signaling in this hematological disease

  5. Findings suggest that RIN1 orchestrates RAB5 (show RAB5A ELISA Kits) activation, ABL kinase activation and BIN1 (show BIN1 ELISA Kits) recruitment to determine EGFR (show EGFR ELISA Kits) fate.

  6. over-expression of RIN1 may play an important role in the progression of non-small cell lung cancer and RIN1 expression may offer a valuable marker for predicting the outcome of patients with NSCLC

  7. RIN1 plays an important role in gastric adenocarcinoma progression and that a high RIN1 expression predicts an unfavorable prognosis in gastric adenocarcinoma patients.

  8. RIN1 expression could be a potential prognostic predictor for the melanoma patients and provide a potential target therapy for melanoma treatment.

  9. RIN1 expression could be a potential prognostic predictor for bladder urothelial carcinoma (UC) patients.

  10. These data identify a novel PKD signaling pathway through RIN1 and Abl kinases that is involved in the regulation of actin remodeling and cell migration.

Mouse (Murine) Ras and Rab Interactor 1 (RIN1) interaction partners

  1. BCR (show BCR ELISA Kits)-ABL1 (show ABL1 ELISA Kits) kinase activity is regulated by RIN1

  2. These results provide insight into regulated expression of Rin1, define a promoter useful in telencephalic neuron studies, and describe a novel REST site variant directing expression to mature neurons.

  3. This study provided evidence that Rin1 normally functions as a negative regulator of fear learning and memory (Rin1-/- mice have enhanced fear conditioning and diminished fear extinction).

  4. Rin1 links histone ubiquitylation to gene silencing and X inactivation.

  5. RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration.

  6. the EphA4 (show EPHA4 ELISA Kits) receptor is required for synaptic plasticity in the amygdala, raising the possibility that an underlying mechanism of Rin1 function in amygdala is to down-regulate EphA4 (show EPHA4 ELISA Kits) signaling by promoting its endocytosis.

RIN1 Antigen Profile

Antigen Summary

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Gene names and symbols associated with RIN1

  • Ras and Rab interactor 1 (RIN1) antibody
  • Ras and Rab interactor 1 (Rin1) antibody
  • RIN1 antibody

Protein level used designations for RIN1

Ras and Rab interactor 1 , ras and Rab interactor 1-like , ras and Rab interactor 1 , ras inhibitor 1 , ras inhibitor JC99 , ras inhibitor RIN1 , ras interaction/interference protein 1 , ras inhibitor

611928 Canis lupus familiaris
714321 Macaca mulatta
100058267 Equus caballus
100395614 Callithrix jacchus
100437658 Pongo abelii
100482238 Ailuropoda melanoleuca
9610 Homo sapiens
225870 Mus musculus
207119 Rattus norvegicus
100520715 Sus scrofa
509295 Bos taurus
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