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May enhance the cell surface expression of odorant receptors (By similarity). Additionally we are shipping REEP6 Antibodies (9) and and many more products for this protein.
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Depletion of receptor accessory proteins REEP5 (show REEP5 Proteins) and REEP6 causes a decrease in CXC Chemokine Receptor 1 (CXCR1 (show CXCR1 Proteins)) signaling.
study implicates REEP6 in retinal homeostasis and highlights a pathway previously uncharacterized in retinal dystrophy (show MERTK Proteins)
DP1L1 polymorphisms are associated with colon cancer and IBD. This indicates that DP1L1 plays a functional role in these conditions. Thus DP1L1 may be a diagnostic and therapeutic target for colon cancer and IBD.
Data suggest that REEP6 plays an essential role in maintaining cGMP homeostasis though facilitating the stability and/or trafficking of guanylate cyclases and maintaining ER and mitochondrial homeostasis.
whole exome sequencing identified homozygous REEP6-E75K mutation in two retinitis pigmentosa families of different ethnicities. Our studies suggest a critical function of REEP6 in trafficking of cargo via a subset of Clathrin-coated vesicles to selected membrane sites in retinal rod photoreceptors.
REEP6.1 is a key functional target of NRL (show NRL Proteins)-centered transcriptional regulatory network in rod photoreceptors.
TB2 (show REEP5 Proteins)-like 1 is a membrane protein that belongs to the YOP1/TB2/DP1 (show REEP5 Proteins)/HVA22 family, and it probably plays an important role in intracellular membrane trafficking in RGCs
May enhance the cell surface expression of odorant receptors (By similarity).
deleted in polyposis 1-like 1
, polyposis locus protein 1-like 1
, receptor expression enhancing protein 6
, receptor expression-enhancing protein 6
, TB2 protein-like 1