anti-Retinol Dehydrogenase 10 (All-Trans) (RDH10) Antibodies

RDH10 encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Additionally we are shipping Retinol Dehydrogenase 10 (All-Trans) Proteins (9) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RDH10 157506 Q8IZV5
RDH10 98711 Q8VCH7
RDH10 353252 Q80ZF7
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Top anti-Retinol Dehydrogenase 10 (All-Trans) Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RDH10 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart 100 μL 2 to 3 Days
$289.00
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Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
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Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
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Bat Rabbit Un-conjugated IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-RDH10 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. ... 100 μL 11 to 14 Days
$727.83
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Human Rabbit Un-conjugated FACS, IHC (p), WB RDH10 Antibody (Center) (ABIN650935) western blot analysis in WiDr,NCI-H460,HepG2 cell line lysates (35 µg/lane).This demonstrates the RDH10 antibody detected the RDH10 protein (arrow). RDH10 Antibody (Center) (ABIN650935) immunohistochemistry analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of human kidney tissue, using RDH10 antibody. ABIN6272949 at 1/100 staining Mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis in Y79 cell line lysates (35ug/lane). RDH10 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
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Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using RDH10 antibody (ABIN5998680) at 1/1000 dilution. 100 μL 11 to 18 Days
$426.40
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Details

More Antibodies against Retinol Dehydrogenase 10 (All-Trans) Interaction Partners

Human Retinol Dehydrogenase 10 (All-Trans) (RDH10) interaction partners

  1. increased expression of ALDH1A1-RDH10-RARalpha- PPARbeta/delta pattern could be considered as adverse prognostic factor associated with a higher concentration of paraprotein and worst overall survival of patients with newly diagnosed multiple myeloma.

  2. In close proximity to RDH10 gene on human chromosome 8 are located two genes that are phylogenetically related to RDH10. The predicted protein products of these genes, retinol dehydrogenase epidermal 2 (RDHE2, SDR16C5) and retinol dehydrogenase epidermal 2-similar (RDHE2S, SDR16C6), share 59% and 56% sequence similarity with RDH10.

  3. the bifunctional nature of retinoid oxidoreductase complex provides the RA-based signaling system with robustness by safeguarding appropriate RA concentration despite naturally occurring fluctuations in RDH10 and DHRS3.

  4. Taken together, our findings demonstrate that RDH10 is essential during the early stages of facial morphogenesis for the formation of a functional nasal airway, and furthermore establish Rdh10 mutant mice as an important model system to study choanal atresia (CA) .

  5. Insulin inhibits retinoic acid biosynthesis through inhibition of FoxO1-induced Rdh10 gene expression.

  6. Data indicate that retinaldehyde reductase (DHRS3) requires retinol dehydrogenase 10 (RDH10) for full enzymatic activity and, in turn, activates RDH10.

  7. all three proteins (RDH10, RALDH2, and CRABP2) appeared to be required for ATRA production induced by activation of PPARgamma

  8. Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture.

  9. CYP4Z1, KIR and RDH10 could play a role in non-small-cell lung cancer progression

  10. organization of the gene includes a unique transcriptional start site, a coding region with six translated exons and a 3' UTR containing at least two used polyadenylation sites.

  11. Forced over-expression of the RDH10 gene causes growth arrest of HepG2 cells and could be a possible curative strategy for hepatocellular carcinoma.

  12. dual physiological role for RDH10: in the biosynthesis of 11-cis-retinaldehyde for vision as well as the biosynthesis of all-trans-retinoic acid for differentiation and development

  13. wild-type RDH10 catalysed both oxidation of all-trans-retinol and reduction of all-trans-retinal in a cofactor-dependent manner In vitro, however, oxidation is the favoured reaction catalysed by RDH10

Mouse (Murine) Retinol Dehydrogenase 10 (All-Trans) (RDH10) interaction partners

  1. 11-cis-retinol is oxidized selectively in cones to the 11-cis-retinal used for pigment regeneration; RDH10 is not the enzyme responsible for this oxidation.

  2. RDH10 and Retinoic acid are required for salivary gland initiation.

  3. Embryonic fibroblasts from Rdh10 heterozygote hypomorphs or with a total Rdh10 knockout exhibit decreased all-trans-retinoic acid biosynthesis and escalated adipogenesis.

  4. Rdh10 null mutant mouse embryos exhibited dorsal pancreas agenesis and a hypoplastic ventral pancreas with retarded tubulogenesis and branching. Conditional disruption of Rdh10 from the endoderm caused increased mortality, reduced body weight, and lowered blood glucose levels after birth. Endodermal Rdh10 deficiency led to a smaller dorsal pancreas with a reduced density of early glucagon(+) and insulin(+) cells.

  5. Taken together, our findings demonstrate that RDH10 is essential during the early stages of facial morphogenesis for the formation of a functional nasal airway, and furthermore establish Rdh10 mutant mice as an important model system to study choanal atresia (CA)

  6. RDH10 acts in cooperation with other RDH isoforms to produce the 11-cis-retinal chromophore needed for vision.

  7. Insulin inhibits retinoic acid biosynthesis through inhibition of FoxO1-induced Rdh10 gene expression.

  8. all three proteins (RDH10, RALDH2, and CRABP2) appeared to be required for ATRA production induced by activation of PPARgamma

  9. Rdh10-/- embryos demonstrate that RA controls hindbrain but not early forebrain patterning, while studies on retinaldehyde-rescued Rdh10-/- embryos show that meningeal RA synthesis is unnecessary to stimulate forebrain cortical expansion.

  10. Retinol dehydrogenase 10 is indispensible for spermatogenesis in juvenile males.

  11. retinol dehydrogenase Rdh10 localizes to lipid droplets during acyl ester biosynthesis

  12. RDH10-mediated oxidation of retinol plays as important a role in the control and regulation of retinoic acid production during embryogenesis as does the subsequent RALDH-mediated reaction.

  13. identified a missense mutation in the Rdh10 gene (Rdh10(m366Asp) ) using an N-ethyl-N-nitrosourea-induced forward genetic screen that result in reduced RA levels and signaling during embryonic development

  14. Retinol dehydrogenase 10 is involved in embryonic patterning and its loss of function can be rescued by maternal retinaldehyde treatment.

  15. Using protein modeling, enzymatic assays, and mutant embryos, we determined that RDH10(trex) mutant protein lacks the ability to oxidize retinol to retinal, resulting in insufficient retinoic acid signaling.

  16. findings show show that the gene encoding Rdh10 is expressed according to complex profiles both during early embryogenesis and organ differentiation

  17. The distribution of Rdh10 transcripts during brain and sensory organ development is consistent with a role of this enzyme in generating region-specific pools of retinaldehyde that will be used by the various RALDHs to refine the patterns of RA synthesis.

Retinol Dehydrogenase 10 (All-Trans) (RDH10) Antigen Profile

Protein Summary

This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development.

Gene names and symbols associated with RDH10

  • retinol dehydrogenase 10b (rdh10b) antibody
  • retinol dehydrogenase 10 (MCYG_00691) antibody
  • retinol dehydrogenase 10 (RDH10) antibody
  • retinol dehydrogenase 10 (all-trans) (Rdh10) antibody
  • retinol dehydrogenase 10 (Rdh10) antibody
  • retinol dehydrogenase 10 (all-trans) (RDH10) antibody
  • 3110069K09Rik antibody
  • 4921506A21Rik antibody
  • AI875664 antibody
  • AW549993 antibody
  • cb804 antibody
  • D1Ertd762e antibody
  • m366Asp antibody
  • rdh10 antibody
  • SDR16C4 antibody

Protein level used designations for RDH10

retinol dehydrogenase 10 , retinol dehydrogenase 10-B , retinol dehydrogenase 10 (all-trans) , retinol dehydrogenase 10-like , short chain dehydrogenase/reductase family 16C, member 4

GENE ID SPECIES
378722 Danio rerio
9223482 Arthroderma otae CBS 113480
100409203 Callithrix jacchus
157506 Homo sapiens
486998 Canis lupus familiaris
100127136 Sus scrofa
282852 Bos taurus
98711 Mus musculus
353252 Rattus norvegicus
420183 Gallus gallus
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