anti-SAM and SH3 Domain Containing 1 (SASH1) Antibodies

May have a role in a signaling pathway. Additionally we are shipping SASH1 Kits (4) and SASH1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SASH1 23328 O94885
SASH1 70097 P59808
SASH1 365037  
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Top anti-SASH1 Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IP, IHC Immunohistochemistry-Paraffin: SASH1 Antibody [NBP1-26651] - FFPE sections of human breast carcinoma. 100 μL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated IHC (p), WB SASH1 Antibody (Center)  western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SASH1 antibody detected the SASH1 protein (arrow). SASH1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SASH1 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IP, WB 100 μL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human placenta tissue stained with SASH1 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of SASH1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of SASH1 Antibody (Center) Cat.-No AP53800PU-N in Mouse liver tissue lysates (35 µg/lane). This demonstrates the SASH1 antibody detected the SASH1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Mouse Rabbit Un-conjugated WB Mouse Sash1 Antibody (C-term)  western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the Sash1 antibody detected the Sash1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: SASH1 Antibody [NBP1-85182] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Immunohistochemistry-Paraffin: SASH1 Antibody  - Staining of human placenta shows cytoplasmic positivity in trophoblastic cells. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: SASH1 Antibody [NBP1-85183] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: SASH1 Antibody [NBP1-85183] - Staining of human placenta shows strong nuclear positivity in trophoblastic cells. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.84 KDa) . 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$658.43
Details

Top referenced anti-SASH1 Antibodies

  1. Human Polyclonal SASH1 Primary Antibody for ICC, IF - ABIN439801 : Weidmann, Touat-Hamici, Durand, Mueller, Chardonnet, Pionneau, Charlotte, Janssen, Verdugo, Cambien, Blankenberg, Tiret, Zeller, Ninio: SASH1, a new potential link between smoking and atherosclerosis. in Atherosclerosis 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal SASH1 Primary Antibody for IP, WB - ABIN439800 : Ascano, Mukherjee, Bandaru, Miller, Nusbaum, Corcoran, Langlois, Munschauer, Dewell, Hafner, Williams, Ohler, Tuschl: FMRP targets distinct mRNA sequence elements to regulate protein expression. in Nature 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal SASH1 Primary Antibody for ELISA, WB - ABIN565047 : Zhou, Wei, Deng, Wang, Zai, Wang, Guo, Zhang, Zhong, He, Xing: SASH1 regulates melanocyte transepithelial migration through a novel G?s-SASH1-IQGAP1-E-Cadherin dependent pathway. in Cellular signalling 2013 (PubMed)

More Antibodies against SASH1 Interaction Partners

Human SAM and SH3 Domain Containing 1 (SASH1) interaction partners

  1. findings suggested that SASH1 can be useful as a new prognostic marker and therapeutic target in cervical cancer patients.

  2. Data show that SAM and SH3 domain containing 1 protein (SASH1) binds with mitogen-activated protein kinase kinase 2 (MAP2K2), and SASH1 mutations promote binding between SASH1 and MAP2K2.

  3. SASH1 is prognostic in breast cancer and could have subtype-dependent effects on breast cancer progression.

  4. SASH1 may inhibit hepatocarcinoma cell invasion and metastasis through down-regulating the Shh-Gli1 and PI3K-AKT pathways

  5. Case Report: SASH1 missense mutation in a Chinese Family with multiple lentigines.

  6. SASH1 acts through NOTCH1 and its inhibitor DLK1 in a three-dimensional model of lumenogenesis involving CEACAM1.

  7. SASH1 is cleaved by caspase-3 following Ultraviolet C-induced apoptosis.

  8. a novel p53/POMC/Galphas/SASH1 autoregulatory positive feedback loop is regulated by SASH1 mutations to induce pathological hyperpigmentation phenotype.

  9. Overexpression of SASH1 inhibits TGF-beta1-induced EMT.

  10. Overexpression of SASH1 suppressed the expression of Shh.

  11. The loss or inhibition of SASH1 expression may play an important role in thyroid cancer development, invasion, and metastasis.

  12. Two SNPs were significantly associated with rotator cuff tearing, residing in SAP30BP on chromosome 17 and SASH1 on chromosome 6.

  13. SASH1 expression is increased in atherosclerotic carotids in smokers and its silencing affects endothelial angiogenic functions

  14. SASH1 expression strongly correlated with glioma grades, showing higher expression at a lower grade.

  15. Data suggest that SASH1 (SAM and SH3 domain-containing protein 1) should be added to the list of genes responsible for autosomal-dominant and -recessive genodermatosis.

  16. SASH1 Is Involved in an Autosomal Dominant Lentiginous Phenotype.

  17. Propose that increase of DNA methylation level in the promoter region of gene SASH1, particularly CpG_26.27 or CpG_54.55 sites, possibly repressed SASH1 expression in breast cancer.

  18. The SASH1 gene is blocked cyclin B1-Cdc2 binding, either directly or indirectly, leading to G2/M arrest.

  19. SASH1 regulates IQGAP1-E-Cadherin signalling and crosstalking between GPCR signalling, calmodulin signalling for the modulation of melanocytes invasion.

  20. Overexpression of SASH1 might be associated with the inhibition of growth, proliferation, and invasion osteosarcoma cells.

Mouse (Murine) SAM and SH3 Domain Containing 1 (SASH1) interaction partners

  1. SASH1 acts to assemble a signaling complex downstream of TLR4 to activate early endothelial responses to receptor activation.

  2. Not expressed in the investigated haematopoietic cell lines, while transcripts were found in whole splenic B-cells from both wild type and Btk-defective mice.

SASH1 Antigen Profile

Protein Summary

May have a role in a signaling pathway. Could act as a tumor suppressor.

Gene names and symbols associated with SASH1

  • SAM and SH3 domain containing 1a (sash1a) antibody
  • SAM and SH3 domain containing 1 (SASH1) antibody
  • SAM and SH3 domain containing 1 (sash1) antibody
  • SAM and SH3 domain containing 1 (Sash1) antibody
  • 1100001C18Rik antibody
  • 2500002E12Rik antibody
  • A330076K04Rik antibody
  • dJ323M4 antibody
  • dJ323M4.1 antibody
  • fi33a01 antibody
  • ik:tdsubc_2e1 antibody
  • MGC162728 antibody
  • mKIAA0790 antibody
  • RGD1566017 antibody
  • SH3D6A antibody
  • tdsubc_2e1 antibody
  • wu:fi33a01 antibody
  • xx:tdsubc_2e1 antibody

Protein level used designations for SASH1

SAM and SH3 domain containing 1 , SAM and SH3 domain-containing protein 1-like , 2500002E12Rik , SAM and SH3 domain-containing protein 1 , proline-glutamate repeat-containing protein , putative adapter and scaffold protein 1

GENE ID SPECIES
557132 Danio rerio
100230822 Taeniopygia guttata
100413411 Callithrix jacchus
100469850 Ailuropoda melanoleuca
100540632 Meleagris gallopavo
100553892 Anolis carolinensis
100596695 Nomascus leucogenys
23328 Homo sapiens
70097 Mus musculus
421621 Gallus gallus
608649 Canis lupus familiaris
539603 Bos taurus
365037 Rattus norvegicus
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