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SARS-CoV-2 Spike S1 Proteins

(SARS-CoV-2 Spike S1)
attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32075877, PubMed:32155444). Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651). Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
SARS-CoV-2 Spike S1 Protein (His tag) SARS-CoV-2 Spike S1 Protein (His tag) SARS-CoV-2 Spike S1 Protein (His tag) (ABIN6952427)

Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. SDS, Func

SARS-CoV-2 Spike S1 Protein (RBD) (His-SUMOstar Tag) SARS-CoV-2 Spike S1 Protein (RBD) (His-SUMOstar Tag) SARS-CoV-2 Spike S1 Protein (RBD) (His-SUMOstar Tag) (ABIN6953166)

Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: Yeast Recombinant Greater than 85 % as determined by SDS-PAGE.

SARS-CoV-2 Spike S1 Protein (RBD) (His tag,MYC tag) SARS-CoV-2 Spike S1 Protein (RBD) (His tag,MYC tag) SARS-CoV-2 Spike S1 Protein (RBD) (His tag,MYC tag) (ABIN6953168)

Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: Mammalian Cells Recombinant Greater than 90 % as determined by SDS-PAGE.

SARS-CoV-2 Spike S1 Proteins by Origin

Find SARS-CoV-2 Spike S1 Proteins for a variety of species such as anti-SARS Coronavirus-2 (SARS-CoV-2) SARS-CoV-2 Spike S1, anti-SARS Coronavirus (SARS-CoV) SARS-CoV-2 Spike S1, anti-SARS CoV-2 Omicron SARS-CoV-2 Spike S1. The species listed below are among those available. Click on a link to go to the corresponding products.

SARS-CoV-2 Spike S1 Proteins by Source

Here you will find SARS-CoV-2 Spike S1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SARS-CoV-2 Spike S1 Proteins by Protein Type

Here you can find SARS-CoV-2 Spike S1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SARS-CoV-2 Spike S1 Proteins by Application

Find SARS-CoV-2 Spike S1 Proteins validated for a specific application such as SDS, ELISA, WB, Func. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SARS-CoV-2 Spike S1 Proteins by Biological Activity

Find SARS-CoV-2 Spike S1 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular SARS-CoV-2 Spike S1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (9)
  • (6)
Cat. No. ABIN6952427
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source Yeast
Validations
  • (5)
Cat. No. ABIN6953166
Quantity 1 mg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source Mammalian Cells
Validations
  • (5)
Cat. No. ABIN6953168
Quantity 1 mg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274393
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (5)
  • (4)
Cat. No. ABIN6952456
Quantity 200 μg
Datasheet Datasheet
Reactivity SARS Coronavirus (SARS-CoV)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275552
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274394
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274391
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275137
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273920
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274778
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274459
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274404
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273902
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274405
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SARS-CoV-2 Spike S1 Proteins

Erickson, Logsdon, Rhea, Hansen, Holden, Banks, Smith, German, Farr, Morley, Weaver, Hirsch, Kovac, Kontsekova, Baumann, Omer, Raber: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).

Fan, Parr, Kang, Gupta: "Point-of-care (POC) SARS-CoV-2 antigen detection using functionalized aerosol jet-printed organic electrochemical transistors (OECTs)." in: Nanoscale, Vol. 15, Issue 11, pp. 5476-5485, (2023) (PubMed).

Kaneko, Satta, Komuro, Muthukrishnan, Kakarla, Guo, An, Elahi, Kornblum, Liebeskind, Hsiai, Hinman: "Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection." in: Stroke, Vol. 52, Issue 1, pp. 260-270, (2021) (PubMed).

Sasisekharan, Pentakota, Jayaraman, Tharakaraman, Wogan, Narayanasami: "Orthogonal immunoassays for IgG antibodies to SARS-CoV-2 antigens reveal that immune response lasts beyond 4 mo post illness onset." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Issue 5, (2021) (PubMed).

Dogan, Kozhaya, Placek, Gunter, Yigit, Hardy, Plassmeyer, Coatney, Lillard, Bukhari, Kleinberg, Hayes, Arditi, Klapper, Merin, Liang, Gupta, Alpan, Unutmaz: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).

Narang, James, Balmer, Wilson: "Protein Footprinting, Conformational Dynamics, and Core Interface-Adjacent Neutralization "Hotspots" in the SARS-CoV-2 Spike Protein Receptor Binding Domain/Human ACE2 Interaction." in: Journal of the American Society for Mass Spectrometry, (2021) (PubMed).

Fiedler, Piziorska, Denninger, Morgunov, Ilsley, Malik, Schneider, Devenish, Meisl, Kosmoliaptsis, Aguzzi, Fiegler, Knowles: "Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum." in: ACS infectious diseases, (2021) (PubMed).

Lucas, Klein, Sundaram, Liu, Wong, Silva, Mao, Oh, Mohanty, Huang, Tokuyama, Lu, Venkataraman, Park, Israelow, Vogels, Muenker, Chang, Casanovas-Massana, Moore, Zell, Fournier, Wyllie, Campbell, Lee et al.: "Delayed production of neutralizing antibodies correlates with fatal COVID-19. ..." in: Nature medicine, (2021) (PubMed).

Song, Bartley, Chow, Ngo, Jiang, Zamecnik, Dandekar, Loudermilk, Dai, Liu, Sunshine, Liu, Wu, Hawes, Alvarenga, Huynh, McAlpine, Rahman, Geng, Chiarella, Goldman-Israelow, Vogels, Grubaugh et al.: "Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms. ..." in: Cell reports. Medicine, pp. 100288, (2021) (PubMed).

Guo, Huang, Zhang, Yao, Zhou, Shen, Shen, Li, Li, Zhang, Chen, Chen, Wu, Fu, Zeng, Feng, Pi, Wang, Zhou, Lu, Li, Fang, Lu, Hu, Wang, Zhang, Gao, Adrian, Wang, Yu, Peng, Gabibov, Min, Wang, Huang et al.: "A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. ..." in: Nature communications, Vol. 12, Issue 1, pp. 2623, (2021) (PubMed).

Aliases for SARS-CoV-2 Spike S1 Proteins

Surface Glycoprotein (S) Proteins
E2 Proteins
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