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GTPase-activating protein for RhoA and Cdc42 small GTPases. Additionally we are shipping SRGAP1 Proteins (4) and and many more products for this protein.
Showing 10 out of 50 products:
Cow (Bovine) Polyclonal SRGAP1 Primary Antibody for WB - ABIN611096
Boyd, Malstrom, Subramanian, Venkatesh, Schaeper, Elangovan, DSa-Eipper, Chinnadurai: Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. in Cell 1994
Show all 2 Pubmed References
Human Monoclonal SRGAP1 Primary Antibody for IF, ELISA - ABIN528215
Hwang, Kohl, Fan, Vivante, Chan, Dworschak, Schulz, van Eerde, Hilger, Gee, Pennimpede, Herrmann, van de Hoek, Renkema, Schell, Huber, Reutter, Soliman, Stajic, Bogdanovic, Kehinde, Lifton, Tasic, Lu et al.: Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract. ... in Human genetics 2015
Human Monoclonal SRGAP1 Primary Antibody for IHC (p), ELISA - ABIN566130
Dai, Ma, Chen, Mi, Fu, Cui, Jin: A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1. in Molecular and cellular neurosciences 2014
Human Polyclonal SRGAP1 Primary Antibody for IP, WB - ABIN253121
Fan, Yang, Kumar, Tumelty, Pisarek-Horowitz, Rasouly, Sharma, Chan, Tyminski, Shamashkin, Belghasem, Henderson, Coyle, Salant, Berasi, Lu: SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. in JCI insight 2016
Results show that the protein expression of srGAP1 is remarkably decreased in 47.5% of colorectal cancer (CRC (show CALR Antibodies)) tissues compared and is found to be associated with tumor progression and poor prognosis.
we identified a consistently replicated loci at 12q14.2 (rs11175194 in SRGAP1, P(meta) = 1.14 x 10(-7))
Mutations of the SLIT2 (show SLIT3 Antibodies)-ROBO2 (show ROBO2 Antibodies) pathway genes SLIT2 (show SLIT3 Antibodies) and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract
The elevated miR (show MLXIP Antibodies)-145 present in invasive glioblastoma cells (IM3 cells) targets and down-regulated srGAP1, thereby allowing downstream G-proteins to remain in their active state and promote the observed invasive phenotype
The interaction of betaPix (show ARHGEF7 Antibodies) with srGAP1 is critical for maintaining suppressive crosstalk between Cdc42 (show CDC42 Antibodies) and RhoA (show RHOA Antibodies) during 3D collagen migration.
Data indicate that srGAP1 possesses a GAP activity specific to Rac1 and is recruited to lamellipodia in a Rac1-dependent manner.
genome-wide linkage analysis in populations in Ohio and Poland: Data suggest that missense mutations in SRGAP1 are associated with genetic predisposition to papillary thyroid carcinoma.
This study proposed that the expression of SRGAP1 in the anterior neocortex may mark the early location of the human motor cortex, including its corticospinal projection neurons, allowing further study of their early differentiation.
FNBP2, ARHGAP13, ARHGAP14 and ARHGAP4 constitute the FNBP2 family characterized by FCH, RhoGAP and SH3 domains.
Mutations of the SLIT2 (show SLIT2 Antibodies)-ROBO2 (show ROBO2 Antibodies) pathway genes SLIT2 (show SLIT2 Antibodies) and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract
srGAP1 and srGAP3 (show SRGAP3 Antibodies) are largely expressed in subpopulations of dorsal root ganglion neurons following sciatic nerve lesion.
Data show that srGAP3 (show SRGAP3 Antibodies) is expressed in ventricular zones of neurogenesis in many different tissues of the central nervous system.
GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.
SLIT-ROBO Rho GTPase-activating protein 1
, SLIT-ROBO Rho GTPase activating protein 1
, SLIT-ROBO Rho GTPase-activating protein 1-like
, rho GTPase-activating protein 13
, Rho GTPase activating protein 13
, Rho GTPase activating protein