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The protein encoded by SMARCC2 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Additionally we are shipping SMARCC2 Antibodies (37) and many more products for this protein.
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our data showed that Swi3 (show SMARCC1 Proteins) strongly affects haem/oxygen-dependent activation of respiration gene promoters whereas Swi2 (show SMARCA1 Proteins) affects only the basal, haem-independent activities of these promoters. using computational analysis and RNAi knockdown, we showed that the mammalian Swi3 BAF155 (show SMARCC1 Proteins) and BAF170 regulate respiration in HeLa cells.
BAF170 is important for neurogenesis in embryonic olfactory epithelium.
Identification of frameshift mutations in the SMARCC2 gene in gastric and colorectal cancers with microsatellite instability.
study finds Baf53 (show BAF53A Proteins) and Baf170 are highly regulated in HIV-1-infected cells
protein levels of BAF155 (show SMARCC1 Proteins)/170 dictate the maximum cellular amount of BAF57 (show SMARCE1 Proteins)
BAF170 mediates the interaction between BAF (show BANF1 Proteins) complexes and H3K27demethylases, controlling the global level of H3K27me2/3 and ultimately the gene expression program in cortical development.
Data show that knockdown of component of chromatin remodeling complex Brm (show SMARCA2 Proteins) or Baf170 at different stages promotes reprogramming.
BAF170 acts within a precise time window to repress indirect cortical neurogenesis, and control cortical size.
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
, BRG1-associated factor 170
, SWI/SNF complex 170 kDa subunit
, SWI/SNF complex subunit SMARCC2
, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2
, SWI3-like protein
, chromatin remodeling complex BAF170 subunit
, mammalian chromatin remodeling complex BRG1-associated factor 170