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The protein encoded by SCARF2 is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Additionally we are shipping Scavenger Receptor Class F, Member 2 Antibodies (33) and Scavenger Receptor Class F, Member 2 Kits (4) and many more products for this protein.
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the full VDEGS phenotype may include sclerocornea resulting from homozygosity or compound heterozygosity for loss of function variants in SCARF2.
Mutations in SCARF2 are responsible for Van Den Ende-Gupta syndrome.
SRECII binds to SRECI and has a similar tissue distribution pattern
binds to SRECI and has a similar tissue distribution pattern
role of scavenger receptor expressed by endothelial cells I (SREC-I) in the uptake of modified lipoproteins as well as in the development of atherosclerosis
SREC-I is a type F scavenger receptor and an endocytic receptor for calreticulin
The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
scavenger receptor class F member 2
, scavenger receptor expressed by endothelial cells 2 protein
, scavenger receptor class F, member 1
, scavenger receptor expressed by endothelial cells 2 (acetyl LDL receptor like)
, scavenger receptor type F