anti-Secretogranin II (SCG2) Antibodies

The protein encoded by SCG2 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Additionally we are shipping Secretogranin II Kits (37) and Secretogranin II Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCG2 7857 P13521
SCG2 24765 P10362
SCG2 20254 Q03517
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Top anti-Secretogranin II Antibodies at antibodies-online.com

Showing 10 out of 115 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SCG2 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate WB Suggested Anti-SCG2  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Chromogranin C Antibody [NBP2-15895] - Antibody detects SCG2 protein at cytosol on U87 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded U87 xenograft. Chromogranin C antibody dilution: 1:500. Western Blot: Chromogranin C Antibody [NBP2-15895] - Sample (30 ug of whole cell lysate) A: IMR32 B: U87-MG 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of hromogranin-C Antibody (Center) (ABIN390767) in Ramos cell line lysates (35 µg/lane). SCG2 (arrow) was detected using the purified polyclonal antibody. Chromogranin-C Antibody (Center) (ABIN390767) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$385.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Heart lysate; Primary Ab: 2µg/mL Rabbit Anti-Mouse SCG2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 13 to 16 Days
$360.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry-Paraffin: Chromogranin C Antibody [NBP1-85631] - Staining of human prostate shows strong cytoplasmic and membranous positivity in glandular cells. Western Blot: Chromogranin C Antibody [NBP1-85631] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Chromogranin C antibody detects SCG2 protein at cytosol on rat RT2 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded rat RT2 xenograft. Chromogranin C antibody , dilution: 1:500. IHC-P Image Chromogranin C antibody detects SCG2 protein at cytosol on mouse brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain tissue. Chromogranin C antibody , dilution: 1:500. 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Anti-SCG2 / Secretogranin II antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml. 50 μL Log in to see 11 to 14 Days
$484.00
Details

Top referenced anti-Secretogranin II Antibodies

  1. Human Polyclonal SCG2 Primary Antibody for ELISA, WB - ABIN4298666 : Guillemot, Thouënnon, Guérin, Vallet-Erdtmann, Ravni, Montéro-Hadjadje, Lefebvre, Klein, Muresan, Seidah, Anouar, Yon: Differential expression and processing of secretogranin II in relation to the status of pheochromocytoma: implications for the production of the tumoral marker EM66. in Journal of molecular endocrinology 2012 (PubMed)

More Antibodies against Secretogranin II Interaction Partners

Human Secretogranin II (SCG2) interaction partners

  1. Differential Reovirus-Specific and Herpesvirus-Specific Activator Protein 1 Activation of Secretogranin II Leads to Altered Virus Secretion.

  2. present data show that SgII is highly expressed in advanced prostate cancer and may contribute to the neuroendocrine differentiation by promoting the formation of secretory granules and the proliferation of PCa cells.

  3. SN induces MUC5AC hypersecretion in a dose- and time-dependent manner; moreover, the MUC5AC over synthesis induced by SN is strongly associated with the enhanced binding of EGF to NRP1

  4. Topical secretoneurin gene therapy accelerates diabetic wound healing by interaction between heparan-sulfate proteoglycans and basic FGF.

  5. Manserin may serve as a marker of prostate cancer progression.

  6. CgA, CgB, and secretoneurin are detectable in feces, and collagenous colitis patients express higher values than patients with inflammatory bowel disease and controls. In treatment, fecal secretoneurin decreased to control levels in collagenous colitis.

  7. In vivo secretoneurin improves left ventricular function, inhibits remodeling, and reduces scar formation; in the infarct border zone, secretoneurin induces coronary angiogenesis.

  8. Circulating Levels of SgII are Increased in Patients with chronic, stable heart failure.

  9. Data describe the gene expression and protein production of SgII in normal adrenal glands and pheochromocytomas with the goal to examine the molecular mechanisms leading to the marked variations in the expression of EM66 in tumoral chromaffin tissue.

  10. This short review deals with investigations in neuroendocrine tumors (NETs) with antibodies against defined epitopes of chromogranins (Cgs) A and B and secretogranins (Sgs) II and III.

  11. More SgII immunoreactive cells were observed in phaeochromocytomas.

  12. Transendothelial migration of leukocytes and signalling mechanisms in response to the neuropeptide secretoneurin.

  13. secretogranin II-derived peptide EM66 generated in human tumoral chromaffin tissue; significant difference in EM66 concentrations between benign and malignant pheochromocytomas

  14. the high concentration of secretoneurin in the aqueous humor indicates a significant role of this peptide

  15. a variant of Secretogranin II has a role in regulation by PHOX2 transcription factors and in hypertension

  16. Results suggest that secretogranin II represents a key AP-1-regulated protein that counteracts nitric oxide toxicity and mediates neuronal differentiation of neuroblastoma cells.

  17. Increased concentrations of SgII, especially the N-terminal part of secretoneurin could be measured in plasma from patients with endocrine pancreatic tumours.

  18. Suppression of Pdcd4 resulted in an increased release of CgA and Sg II and was accompanied by an up-regulation of intracellular PC1.

  19. semiquantitative immunocytochemistry for secretogranin II in amyotrophic lateral sclerosis.

Mouse (Murine) Secretogranin II (SCG2) interaction partners

  1. Scg2 is a major secretory target of REST with a cell differentiation-enhancing activity in neural stem cells.

  2. Topical secretoneurin gene therapy accelerates diabetic wound healing by interaction between heparan-sulfate proteoglycans and basic FGF.

  3. Scg2 is a good candidate for the signal integrator required for activity-dependent plasticity such as associative learning and memory.

  4. SgII binds directly to the secretory granule membrane and controls intracellular retention of proopiomelanocortin in AtT-20 cells.

  5. SgII mRNA levels were 10.5 fold upregulated in the left ventricle of animals with myocardial infarction and heart failure.

  6. it was proven that ScgII cannot be categorized as an activity marker, but more likely plays a role in visual system plasticity by modulating a range of neurotransmitters and neuropeptides

  7. SN activates the protein kinase A (PKA) and cAMP-induced ERK signaling pathways in the LH-secreting mouse LbetaT2 pituitary cell line

  8. The wide subcellular localization of secretogranin II in mouse brain may reflect diverse release sites of neuropeptides and secretorneurin, or suggests its role in the sorting and packaging of molecules other than neuropeptides in non-LDCV compartments.

  9. SCG2, as well as SCG3, may be a potential regulator of food intake based on its capacity to accumulate appetite-related hormones into secretory granules.

Cow (Bovine) Secretogranin II (SCG2) interaction partners

  1. secretogranin II-derived peptide EM66 may act downstream of the trans-synaptic stimulation of the adrenal medulla by neurocrine factors

  2. Results show the localization of secretogranin II (SgII) in the nucleus, more specifically, in the IP3-sensitive nucleoplasmic Ca2+ store vesicles along with CGB and the IP3 receptors.

Pig (Porcine) Secretogranin II (SCG2) interaction partners

  1. Comparative sequencing and EST analysis revealed nine SNPs in porcine SCG2 cDNA, including seven SNPs in the coding region and two SNPs in the 3' UTR.

Secretogranin II (SCG2) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.

Gene names and symbols associated with anti-Secretogranin II (SCG2) Antibodies

  • secretogranin II L homeolog (scg2.L) antibody
  • secretogranin II (chromogranin C), b (scg2b) antibody
  • secretogranin II (scg2) antibody
  • secretogranin II (SCG2) antibody
  • Secretogranin-2 (scg2) antibody
  • secretogranin II (Scg2) antibody
  • Chcg antibody
  • Chgc antibody
  • DKFZp459O193 antibody
  • EM66 antibody
  • LOC397939 antibody
  • MGC84703 antibody
  • MGC145924 antibody
  • SCG2 antibody
  • SCGG2 antibody
  • SgII antibody
  • SN antibody
  • wu:fj34e01 antibody
  • zgc:153925 antibody

Protein level used designations for anti-Secretogranin II (SCG2) Antibodies

secretogranin II , secretogranin-2 , secretogranin-2-like , secretogranin II (chromogranin C) , Secretogranin-2 , chromogranin-C , secretoneurin , Chromogranin C (Secretogranin II) , secretogranin 2 , sgII , chromogranin C

GENE ID SPECIES
397939 Xenopus laevis
777641 Danio rerio
779764 Xenopus (Silurana) tropicalis
100061099 Equus caballus
100484350 Ailuropoda melanoleuca
100559979 Anolis carolinensis
100174732 Pongo abelii
100196607 Salmo salar
7857 Homo sapiens
24765 Rattus norvegicus
20254 Mus musculus
281477 Bos taurus
497237 Sus scrofa
424808 Gallus gallus
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