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SEPT6 is a member of the septin family of GTPases. Additionally we are shipping Septin 6 Proteins (11) and Septin 6 Kits (8) and many more products for this protein.
Showing 10 out of 74 products:
Human Polyclonal SEPT6 Primary Antibody for ELISA, IHC - ABIN4352737
Kremer, Adang, Macara: Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. in Cell 2007
It has been found that Sep2 is uniquely required for follicle cell encapsulation of female germline cysts, and that Sep2 and Sep5 are redundant for follicle cell proliferation.
Results show that Sep2 Sep5 double mutants have an early pupal lethal phenotype and lack imaginal discs, suggesting that these genes have redundant functions during imaginal cell proliferation.
Sept6 is first expressed in the notochord and then in nearly all of the ciliary organs, including Kupffer's vesicle (KV), the pronephros, eye, olfactory bulb, and neural tube. Knockdown of sept6 results in reduced numbers and length of cilia in KV.
MiR (show MLXIP Antibodies)-223-3p might target gene SEPT6 and promoted the biological behavior of prostate cancer.
Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis
The SEPT6 provides the directional guidance cues necessary for polarizing the epithelial microtubule network.
Data show that Septins of the SEPT6 group preferentially interacted with septins of the SEPT2 (show SEPT2 Antibodies) group, SEPT3 (show SEPT3 Antibodies) group and SEPT7 (show SEPT7 Antibodies) group.
MLL (show MLL Antibodies)-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia
Molecular analysis using rtPCR followed by sequencing confirmed the expression of an MLL (show MLL Antibodies)-SEPT6 fusion transcript with a novel sequence.
septin 2 (show SEPT2 Antibodies), 6, and 7 complexes make up polymerized filaments
These results indicate that the host proteins hnRNP A1 (show HNRNPA1 Antibodies) and septin 6 play important roles in the replication of HCV through RNA-protein and protein-protein interactions.
crystal structures of the human SEPT2 (show SEPT2 Antibodies) G domain and the heterotrimeric human SEPT2-SEPT6-SEPT7 (show SEPT7 Antibodies) complex
Demonstrate connection between septins/SOCS7/NCK (show NCK1 Antibodies) signaling and the DNA damage response.
Sept6 did not alter the phenotype of myeloproliferative disease induced by MLL (show MLL Antibodies)-SEPT6, thus suggesting that Sept6 does not function as a tumor suppressor.
Significant level of SEPT6 expression was found in heart in a developmentally regulated fashion.
Data demonstrate that the septin cytoskeleton is an integral component of the myelin sheath, and protein components such as septin 6 interact with distinct myelin constituents such as MAL.
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.
, myosin LC
, septin 2
, septin 11
, septin 6