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Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP..
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Cow (Bovine) Polyclonal SRP19 Primary Antibody for IHC, WB - ABIN2778840
Kuglstatter, Oubridge, Nagai: Induced structural changes of 7SL RNA during the assembly of human signal recognition particle. in Nature structural biology 2002
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The crystal structures of the SRP68 (show SRP68 Antibodies) protein-binding domain (PBD) in complex with SRP72 (show SRP72 Antibodies)-PBD and of the SRP72 (show SRP72 Antibodies)-RBD (show CACNA1D Antibodies) bound to the SRP (show UCN2 Antibodies) S domain (SRP (show UCN2 Antibodies) RNA, SRP19 and SRP68 (show SRP68 Antibodies)) detailing all interactions of SRP72 (show SRP72 Antibodies) within SRP (show UCN2 Antibodies) have been presented.
anti-SRP19 antibody is highly expressed in muscle tissues of patients with autoimmune necrotizing myopathy.
crystal structures of a crenarchaeal and the all-human SRP19-signal recognition particle RNA binary complexes presented here show that the asymmetric loop is bulged out in both binary complexes.
Structure of the SRP19 RNA complex
crystal structure of a human SRP (show UCN2 Antibodies) ternary complex consisting of SRP19, the M domain of SRP54 (show SRP54 Antibodies) and the S domain of 7SL RNA
Data show that the presence of SRP54 (show SRP54 Antibodies) during SRP19-RNA assembly dramatically alters the folding energy landscape to create a non-native folding pathway that leads to an aberrant SRP19-RNA conformation.
1.8 angstrom resolution crystal structure of human SRP19 in complex with its primary binding site on helix 6 of SRP (show UCN2 Antibodies) RNA was determined
srp19 is produced in the amplified nucleoli of Xenopus oocytes, presumably as a global developmental strategy for stockpiling translational machinery for early embryogenesis
Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
signal recognition particle 19 kDa protein
, signal recognition particle 19
, signal recognition particle 19kDa
, signal recognition particle 19 kD protein
, signal recognition particle protein 19