SMG7 ELISA Kits

SMG7 encodes a protein that is essential for nonsense-mediated mRNA decay (NMD)\; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex.

Type
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Antigen
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Reactivity
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Application
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Method Type
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Analytical Method
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Detection Method
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1 Product
Uncoated, Samples: Cell Culture Cells
ReactivityHuman
Detection MethodColorimetric, Cell ELISA
Detection RangeQualitative
Order details Cat. No. ABIN5648325
$380.00
96 tests
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
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SMG7 Antigen Profile

Protein Summary

This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD)\; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with SMG7

  • Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg7) antibody
  • SMG7, nonsense mediated mRNA decay factor (SMG7) antibody
  • 9430023P16Rik antibody
  • C1orf16 antibody
  • EST1C antibody
  • mKIAA0250 antibody
  • SGA56M antibody

Protein level used designations for SMG7

EST1-like protein C , protein SMG7 , EST1 telomerase component homolog C , breast cancer-associated antigen SGA-56M , ever shorter telomeres 1C , smg-7 homolog, nonsense mediated mRNA decay factor

GENE ID SPECIES
226517 Mus musculus
9887 Homo sapiens
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