SMG7 ELISA Kits

SMG7 encodes a protein that is essential for nonsense-mediated mRNA decay (NMD)\; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex.

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SMG7 ELISA Kit (Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (C. Elegans)) ELISA Kit

SMG7 Reactivity: Human Colorimetric Cell ELISA Cell Culture Cells

Catalog No. ABIN5648325

$380.00

Plus shipping costs $45.00

96 tests

Shipping to: United States

Delivery in 2 to 3 Business Days

Details

SMG7 Antigen Profile

Protein Summary

This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD)\; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with SMG7

Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg7) antibody
SMG7, nonsense mediated mRNA decay factor (SMG7) antibody

9430023P16Rik antibody
C1orf16 antibody
EST1C antibody
mKIAA0250 antibody
SGA56M antibody

Protein level used designations for SMG7

EST1-like protein C , protein SMG7 , EST1 telomerase component homolog C , breast cancer-associated antigen SGA-56M , ever shorter telomeres 1C , smg-7 homolog, nonsense mediated mRNA decay factor