Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 10 Proteins (SLC2A10)

SLC2A10 encodes a member of the class III facilitative glucose transporter family. Additionally we are shipping SLC2A10 Antibodies (56) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC2A10 81031 O95528
SLC2A10 170441 Q8VHD6
Rat SLC2A10 SLC2A10 366251  
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Top SLC2A10 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$7,493.38
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

SLC2A10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 10 (SLC2A10) Interaction Partners

Zebrafish Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 10 (SLC2A10) interaction partners

  1. Loss of GLUT10 is associated with impaired cardiovascular system and the notochord and TGFbeta signaling

  2. In later embryonic stages, slc2a10 mRNA was detected in the otic vesicles, hatching gland cells, pectoral fin, posterior tectum and swim bladder.

Human Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 10 (SLC2A10) interaction partners

  1. We delineate the clinical spectrum and describe the histology in arterial tortuosity syndrome (ATS), a rare connective tissue disorder characterized by tortuosity of the large and medium-sized arteries, caused by mutations in SLC2A10

  2. We document a spectrum of ophthalmic manifestations of arterial tortuosity syndrome with universal findings of myopia, corneal thinning, and a propensity for corneal ectasia leading to keratoconus or keratoglobus. Heterozygous carriers may develop keratectasia after corneal refractive surgery

  3. GLUT10 is a dehydroascorbic acid (DAA) transporter and DAA transport is diminished in the endomembranes of fibroblasts from Arterial Tortuosity syndrome patients.

  4. GLUT10 deficiency leads to oxidative stress and non-canonical alphavbeta3 integrin-mediated TGFbeta signalling associated with extracellular matrix disarray in arterial tortuosity syndrome skin fibroblasts

  5. 100 ATS patients have been described, and 21 causal mutations have been identified in the SLC2A10 gene. Study expanded the allelic repertoire of SLC2A10 by identifying two novel mutations.

  6. Two SNPs replicated: the paternal rs2471083-C allele (located near the imprinted KCNK9 gene) and the paternal rs3091869-T allele (located near the SLC2A10 gene) increased BMI equally (beta = 0.11 (SD), P<0.0027)

  7. Data show that homozygous and compound heterozygous changes found in PLOD1 and SLC2A10 may confer autosomal recessive effects, and three MYH11, ACTA2 and COL3A1 heterozygous variants were considered as putative pathogenic gene alterations.

  8. Our data demonstrate that genetic polymorphism of the SLC2A10 gene is an independent risk factor for PAD in type 2 diabetes.

  9. expression in adipose tissue

  10. variation in the coding region of SLC2A10 does not contribute substantially to the pathogenesis of type 2 diabetes

  11. The SLC2A10 gene encodes a glucose transporter and is located on chromosome 20q13, where evidence has been found for linkage to type 2 diabetes (T2D) in multiple studies.

  12. Complex regulatory mechanism of SLC2A10 expression through interaction of multiple transcription factors on basal promotor and prescence of distal repressor sequence suggests fine modulation of GLUT10 levels critical for glucose homeostasis.

  13. GLUT10 deficiency is associated with upregulation of the TGFbeta pathway in the arterial wall, a finding also observed in Loeys-Dietz syndrome, in which aortic aneurysms associate with arterial tortuosity

  14. SLC2A10 genetic variations do not appear to be major determinants for type 2 diabetes susceptibility in the Taiwanese population.

  15. the c.243C>G mutation in the Middle Eastern families may have a common origin and shared ances

  16. analysis of a missense and a recurrent mutation in SLC2A10 gene of patients affected with arterial tortuosity syndrome

  17. Patients of Kurdish origin who display arterial tortuosity associated with skin hyperextensibility, joint hypermobility, and characteristic facial features may carry a novel non-sense mutationin in the SLC2A10 gene.

Mouse (Murine) Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 10 (SLC2A10) interaction partners

  1. Glut10 may contribute to glucose transport from the endolymph to the hair cells across the cuticular plate in the mouse inner ear

  2. GLUT10 protects cells from oxidative injury.

  3. expression in adipose tissue

  4. report that two mouse models, homozygous respectively for G128E and S150F missense substitutions in glut10 do not present any of the vascular, anatomical, or immunohistological abnormalities as encountered in human Arterial tortuosity syndrome patients.

SLC2A10 Protein Profile

Protein Summary

This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.

Gene names and symbols associated with SLC2A10

  • solute carrier family 2 member 10 (SLC2A10)
  • solute carrier family 2 (facilitated glucose transporter), member 10 (slc2a10)
  • solute carrier family 2 (facilitated glucose transporter), member 10 (SLC2A10)
  • solute carrier family 2 (facilitated glucose transporter), member 10 (Slc2a10)
  • solute carrier family 2 member 10 (Slc2a10)
  • AA450473 protein
  • ATS protein
  • Glut10 protein
  • SLC2A10 protein
  • zgc:171488 protein

Protein level used designations for SLC2A10

solute carrier family 2 (facilitated glucose transporter), member 10 , Glut10 , facilitative glucose transporter variant 1 , solute carrier family 2, facilitated glucose transporter member 10 , zglut10 , solute carrier family 2 member 10 , solute carrier family 2, facilitated glucose transporter member 10-like , GLUT-10 , glucose transporter type 10

GENE ID SPECIES
419206 Gallus gallus
485911 Canis lupus familiaris
516135 Bos taurus
560546 Danio rerio
716558 Macaca mulatta
100071243 Equus caballus
100125548 Sus scrofa
100433997 Pongo abelii
100595321 Nomascus leucogenys
81031 Homo sapiens
170441 Mus musculus
366251 Rattus norvegicus
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