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SLC2A9 encodes a member of the SLC2A facilitative glucose transporter family. Additionally we are shipping SLC2A9 Antibodies (76) and and many more products for this protein.
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genetic association studies in population in China: Data suggest that SNPs in SLC2A9 (rs11722228, rs3775948) and ABCG2 (rs2231142) are associated with diabetic kidney disease in subjects with type 2 diabetes in the population studied. (SLC2A9 = solute carrier family 2 member 9; ABCG2 = ATP binding cassette subfamily G (show CYP ELISA Kits) member 2)
This meta-analysis shows that the rs12510549, rs16890979, and rs1014290 polymorphisms of SLC2A9 protect against the development of gout in Caucasians and/or Asians.
The results of the study confirmed the presence of GLUT-1 (show SLC2A1 ELISA Kits), GLUT-4 (show SLC2A4 ELISA Kits) and GLUT-9 proteins in the trophoblast from both, uncomplicated and diabetic pregnancies. In addition, insulin (show INS ELISA Kits) therapy may increase placental expression of GLUT-4 (show SLC2A4 ELISA Kits) and GLUT-9, and partially GLUT-1 (show SLC2A1 ELISA Kits), in women with pregestational and gestational diabetes mellitus.
Meta-analysis. This study demonstrated that the genetic susceptibility for gout is associated with the SLC2A9 gene polymorphisms. Four of them except for the rs3733591 are protective SNPs in Caucasians, and rs16890979 and rs1014290 are protective SNPs in both Caucasians and Asians, while rs3733591 may be susceptibility SNP in Asians.
Each A-allele of the SLC2A9 rs7442295 was associated with 9% higher plasma urate and hazard ratios of 1.07 (1.01-1.14) for cancer incidence and 1.07 (1.02-1.13) for all-cause mortality.
The present proof-of-principle paper demonstrates that the multilocus profiles of ABCG2, SLC2A9 and SLC22A12 (show SLC22A12 ELISA Kits) increase susceptibility to asymptomatic hyperuricaemia, gout and tophi.
Immunostaining and highly-sensitive in situ hybridization was used to assess the distribution of UA transporters: GLUT9/URATv1, ABCG2, and URAT1 (show SLC22A12 ELISA Kits). Immunostaining for GLUT9 was observed in ependymal cells, neurons, and brain capillaries. Immunostaining for ABCG2 was observed in the choroid plexus epithelium and brain capillaries, but not in ependymal cells. These results were validated by in situ hybridization.
The first genome-wide association study for serum uric acid level in Indians revealed association of SLC2A9, SLC22A11 and ABCG2 gene variants at genome wide significance level in Type 2 diabetes patients.
the exon 9 of SLC2A9 gene 109C/T polymorphism is not associated with HUA and diabetes
Demonstrate a significant association between rs2231142 in the ABCG2 gene and gout and identified novel SNPs, c.881A>G and c.1002+78G>A, in the SLC2A9 gene that may be associated with gout in a Korean population.
intestinal uric acid transporter SLC2A9 has a role in early-onset metabolic syndrome in a mouse model
blocking GLUT9 expression during preimplantation development (show MTA2 ELISA Kits) had no effect on glucose transport or apoptosis but transfer of these embryos resulted in increased pregnancy loss, suggesting that GLUT9 is critical for early preimplantation development (show MTA2 ELISA Kits).
Characterize in more detail the transport properties of mouse GLUT9 and provide evidence that it functions as a urate uniporter.
Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy.
This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.
, glucose transporter type 9
, human glucose transporter-like protein-9
, solute carrier family 2, facilitated glucose transporter member 9
, urate voltage-driven efflux transporter 1
, solute carrier family 2 (facilitated glucose transporter), member 9
, solute carrier family 2, member 9 protein
, Solute carrier family 2, facilitated glucose transporter member 9
, facilitated glucose transporter, type 9
, solute carrier family 2, member 9