Solute Carrier Family 20 (Phosphate Transporter), Member 1 Proteins (SLC20A1)

The protein encoded by SLC20A1 is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. Additionally we are shipping SLC20A1 Antibodies (34) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC20A1 6574 Q8WUM9
Rat SLC20A1 SLC20A1 81826 Q9JJP0
SLC20A1 20515 Q61609
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Top SLC20A1 Proteins at antibodies-online.com

Showing 5 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human GLVR1 Protein. 100 μg Log in to see 11 to 18 Days
$540.11
Details
Escherichia coli (E. coli) Mouse Un-conjugated SDS-PAGE analysis of Mouse GLVR1 Protein. 100 μg Log in to see 11 to 18 Days
$568.54
Details

SLC20A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine) ,
, ,

More Proteins for Solute Carrier Family 20 (Phosphate Transporter), Member 1 (SLC20A1) Interaction Partners

Xenopus laevis Solute Carrier Family 20 (Phosphate Transporter), Member 1 (SLC20A1) interaction partners

  1. Cysteine substitution at some sites also altered the apparent affinity for Pi and cation (Na(+)/Li(+)) and substrate (phosphate/arsenate) selectivity, further underscoring the importance of this linker in defining PiT-1 transport characteristics.

Human Solute Carrier Family 20 (Phosphate Transporter), Member 1 (SLC20A1) interaction partners

  1. Targeted sequencing of two candidate genes, SLC20A1 and SLC15A4, of the solute carrier membrane transport protein family in 200 additional patients demonstrated two further variants predicted as damaging for combined hormone deficiency.

  2. Overexpression of SLC20A1 is associated with Estrogen Receptor-positive Breast Cancer.

  3. indoxyl sulfate promotes Pit-1 expression in part by activation of the JNK pathway in vascular smooth muscle cells

  4. Ox-LDL induces an osteogenic change in human aortic valve interstitial cells marked by the induction of PiT-1.

  5. Overexpression of SLC20A1 promotes apoptosis and mineralization by altering the level of Akt-1.

  6. Allelic variations in SLC20A1 were associated with the levels of Sodium-lithium countertransport.

  7. the human PiT2 histidine, H(502), and the human PiT1 glutamate, E(70),--both conserved in eukaryotic PiT family members--are critical for P(i) transport function

  8. Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF-induced apoptosis.

  9. propose that region A of Pit1 confers competence for viral entry by influencing the topology of the authentic binding site in the membrane and hence its accessibility to a viral envelope protein

  10. Two highly conserved glutamate residues critical for sodium-dependent phosphate transport are revealed by uncoupling transport function from retroviral receptor function.

  11. Our results link low-grade IL-8-mediated cartilaginous inflammation in OA to altered chondrocyte differentiation and disease progression through PiT-1 expression and sodium-dependent Pi uptake mediated by CXCR1 signaling.

  12. Phosphate uptake through Pit-1 is essential for vascular smooth muscle cell calcification and phenotypic modulation in response to elevated phosphate.

  13. Results describe the characterization of transport mechanisms and determinants critical for sodium-dependent phosphate symport of the PiT family paralogs human PiT1 and PiT2.

  14. Analysis of kinetics and substrate specificity of SLC20A1.

  15. An overexpression of Pit-1 seems to play a key role in the formation of soft tissue calcification in Werner syndrome.

  16. PiT1 depletion markedly reduces cell proliferation, delays cell cycle, and impairs mitosis and cytokinesis.

SLC20A1 Protein Profile

Protein Summary

The protein encoded by this gene is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. The encoded protein is also a retroviral receptor, causing human cells to be susceptible to infection by gibbon ape leukemia virus, simian sarcoma-associated virus, feline leukemia virus subgroup B, and 10A1 murine leukemia virus.

Gene names and symbols associated with SLC20A1

  • solute carrier family 20 member 1 (SLC20A1)
  • solute carrier family 20 member 1 L homeolog (slc20a1.L)
  • solute carrier family 20 member 1 (Slc20a1)
  • solute carrier family 20, member 1 (Slc20a1)
  • AI607883 protein
  • DKFZp459N1424 protein
  • Glvr-1 protein
  • Glvr1 protein
  • PiT-1 protein
  • PIT1 protein
  • slc20a1 protein
  • xSLC20A1 protein

Protein level used designations for SLC20A1

solute carrier family 20 (phosphate transporter), member 1 , sodium-dependent phosphate transporter 1 , solute carrier family 20 member 1 , sodium-dependent phosphate transporter 1-B , solute carrier family 20 member 1-B , gibbon ape leukemia virus receptor 1 , leukemia virus receptor 1 homolog , RPHO-1 , phosphate transporter 1 , feline leukemia virus subtype-B receptor , leukemia virus-b receptor , piT-1

GENE ID SPECIES
459498 Pan troglodytes
514255 Bos taurus
100586344 Nomascus leucogenys
100173250 Pongo abelii
398846 Xenopus laevis
6574 Homo sapiens
483066 Canis lupus familiaris
81826 Rattus norvegicus
493789 Felis catus
20515 Mus musculus
Selected quality suppliers for SLC20A1 Proteins (SLC20A1)
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