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Solute Carrier Family 22 (Organic Cation Transporter), Member 7 (SLC22A7) ELISA Kits

The protein encoded by SLC22A7 is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. Additionally we are shipping Solute Carrier Family 22 (Organic Cation Transporter), Member 7 Antibodies (29) and Solute Carrier Family 22 (Organic Cation Transporter), Member 7 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SLC22A7 SLC22A7 10864 Q9Y694
Anti-Rat SLC22A7 SLC22A7 89776 Q5RLM2
Anti-Mouse SLC22A7 SLC22A7 108114 Q91WU2
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Top Solute Carrier Family 22 (Organic Cation Transporter), Member 7 ELISA Kits at antibodies-online.com

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More ELISA Kits for Solute Carrier Family 22 (Organic Cation Transporter), Member 7 Interaction Partners

Human Solute Carrier Family 22 (Organic Cation Transporter), Member 7 (SLC22A7) interaction partners

  1. Lrh-1 transcriptionally regulates Oat2.

  2. two human organic anion transporters OAT2 and OAT7 activities were assessed.

  3. SLC22A7 variants were not significantly associated with hyperuricemia and gout in a New Zealand Maori and Pacific cohort.

  4. Two novel variants in SLC22A17 and SLC22A7 were significantly associated with anthracycline-induced cardiotoxicity.

  5. suggest that OAT2-mediated cGMP uptake does not occur via exchange with monocarboxylates, dicarboxylates, and hydroxyl ions

  6. the findings revealed the important role of OAT2 in renal secretion and possible reabsorption of creatinine and suggested a molecular basis for potential species difference in the transporter handling of creatinine

  7. At physiologic creatinine concentrations, specific activity of OAT2 transport was over twofold higher than OCT2 or OCT3, establishing OAT2 as a likely creatinine transporter, challenging the view that creatinine is solely transported by a cationic pathway

  8. mitochondrial pathways may affect SLC 22A7 function to promote the occurrence of hepatocellular carcinoma

  9. Benzoic acid and specific 2-oxo acids activate hepatic efflux of glutamate at OAT2

  10. Transport of the antivirals into human embryonic kidney cells was stimulated 10- to 20-fold by expression of OAT2.

  11. Expression of rat OAT2 in HEK (human embryonic kidney)-293 cells stimulates accumulation of zwitterion trigonelline; subsequently, orotic acid is identified as an excellent and specific substrate of OAT2 from human.

  12. results suggest that genetic polymorphisms may not be a significant contributing factor to variations in the hOAT2 expression or hOAT2 transport activity

  13. elucidation of the molecular mechanism for renal tetracycline transport by human organic anion transporters (hOATs) using proximal tubular cells stably expressing hOATs

  14. hOAT2 is a highly efficient, facilitative transporter of cGMP and may be involved in cGMP signaling in many tissues.

Mouse (Murine) Solute Carrier Family 22 (Organic Cation Transporter), Member 7 (SLC22A7) interaction partners

  1. there exists a sex- and species-related differential gene expression of the OAT2 isoform.

  2. Results indicate that mOAT2 plays a role for the transport of bumetanide on the luminal membranes of kidney proximal tubules.

  3. OAT2 in mouse kidney exhibiting gender differences (F > M) that appear in puberty and are caused by strong androgen inhibition and weak estrogen and progesterone stimulation

  4. propionate (3-carbon SCFA) was transported by mOat2 in a time-dependent manner.

Solute Carrier Family 22 (Organic Cation Transporter), Member 7 (SLC22A7) Antigen Profile

Antigen Summary

The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with SLC22A7

  • solute carrier family 22 member 7 (SLC22A7) antibody
  • solute carrier family 22 member 7 (Slc22a7) antibody
  • solute carrier family 22 (organic anion transporter), member 7 (Slc22a7) antibody
  • solute carrier family 22 (organic anion transporter), member 7 L homeolog (slc22a7.L) antibody
  • solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1 (slc22a7b.1) antibody
  • nlt antibody
  • oat2 antibody
  • oat2e antibody
  • slc22a7 antibody
  • slc22a7b antibody
  • zgc:63958 antibody

Protein level used designations for SLC22A7

hOAT2 , liver-specific transporter , novel liver transporter , organic anion transporter 2 , solute carrier family 22 member 7 , rbOAT2 , mOAT2 , renal organic anion transporter 2 , solute carrier family 22 (organic anion transporter), member 7 L homeolog , solute carrier family 22, member 7-like

GENE ID SPECIES
10864 Homo sapiens
89776 Rattus norvegicus
407224 Bos taurus
100009335 Oryctolagus cuniculus
108114 Mus musculus
100174712 Pongo abelii
481811 Canis lupus familiaris
733693 Sus scrofa
100714866 Cavia porcellus
444396 Xenopus laevis
393320 Danio rerio
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