Solute Carrier Family 47, Member 1 (SLC47A1) ELISA Kits

SLC47A1 is located within the Smith-Magenis syndrome region on chromosome 17. Additionally we are shipping Solute Carrier Family 47, Member 1 Antibodies (43) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SLC47A1 55244 Q96FL8
Anti-Rat SLC47A1 SLC47A1 360539 Q5I0E9
Anti-Mouse SLC47A1 SLC47A1 67473 Q8K0H1
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Top Solute Carrier Family 47, Member 1 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details

Top referenced Solute Carrier Family 47, Member 1 ELISA Kits

  1. Human SLC47A1 ELISA Kit for Sandwich ELISA - ABIN823375 : Lee, Lee, Kim, Lee, Jun, Lee: Multidrug and toxic compound extrusion protein-1 (MATE1/SLC47A1) is a novel flavonoid transporter. in Journal of agricultural and food chemistry 2014 (PubMed)

More ELISA Kits for Solute Carrier Family 47, Member 1 Interaction Partners

Rabbit Solute Carrier Family 47, Member 1 (SLC47A1) interaction partners

  1. MATE1 has an external COOH terminus, consistent with a 13-helix topology, which may influence transporter turnover.

Human Solute Carrier Family 47, Member 1 (SLC47A1) interaction partners

  1. The impact of assay conditions on IC50 determination is negligible, kinetic characteristics differ among used test substrates, and substrate-dependent inhibition exists for MATE1 and MATE2-K, giving valuable insight into the assessment of clinically relevant MATE-mediated drug interactions in vitro.

  2. Pazopanib inhibits OCT2, MATE1 and MATE2-K, which are involved in cisplatin secretion into urine, potentiating cisplatin toxicity.

  3. The 5' CpG island of SLC47A1 acts as an enhancer for SLC47A1, and DNA methylation in the CpG island plays a role in interindividual differences in hepatic SLC47A1 expression.

  4. The combination of ENT1, MATE1 and OCT2 SNPs may serve as a predictive and prognostic marker in metastatic colorectal carcinoma patients treated with TAS-102.

  5. MATE1 is the major transporter for the cellular uptake of imatinib and crucial for the therapeutic success in CML (show BCR ELISA Kits) patients. We suggest that the detailed analysis of MATE1 expression levels and mutations could be a predictor for the response to imatinib therapy.

  6. This study did not identify any of these known SLC47A1 coding SNPs in the Xhosa individuals who participated in this study.

  7. substrate identity exerts comparatively little influence on ligand interaction with MATE1.

  8. MATE1 mRNA levels in peripheral blood cells were significantly higher in patients carrying the minor allele of rs2453579, but not rs2252281, compared to those with other genotypes

  9. MATE1 polymorphisms were associated with hematological toxicity in non-small cell lung cancer patients.

  10. MATE1 rs2289669 may be a significant determinant in the renal clearance of metformin in the case of transporter-mediated drug interactions

Mouse (Murine) Solute Carrier Family 47, Member 1 (SLC47A1) interaction partners

  1. Mate1 mRNA expression was decreased in mice with either the ob/ob model or the methionine/choline deficiency model of nonalcoholic steatohepatitis.

  2. MATE1 was highly expressed in peroxisomes and the endoplasmic reticulum as well as in plasma membranes in the liver and intestine.

  3. [(11)C]Metformin may be useful as a PET probe to non-invasively study the in vivo function of hepatobiliary transport and drug-drug interactions, mediated by MATE1 in future clinical investigations.

  4. Twelve transmembrane helices form the functional core of mammalian MATE1 (multidrug and toxin extruder 1) protein.

  5. Homozygous MATE1 variant could be one of the risk factors for metformin-induced lactic acidosis.

  6. MATE1 mediates the efflux of cisplatin and is involved in cisplatin-induced nephrotoxicity.

  7. mMATE1 is polyspecific H(+)/(organic cation)OC exchanger. Unexpectedly wide distribution of mMATE1 suggests involvement in diverse biological functions other than excretion of OCs from the body. (Multidrug and toxin extrusion 1, MATE1)

  8. mMATE1b is a functional variant of mMATE1 and seems to be the true counterpart to other MATE1 transporters

  9. MATE1 mRNA levels were highest in the kidney, where male expression was higher than female.

  10. This is the first report to demonstrate an essential role of MATE1 in systemic clearance of metformin.

Solute Carrier Family 47, Member 1 (SLC47A1) Antigen Profile

Antigen Summary

This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function.

Gene names and symbols associated with SLC47A1

  • solute carrier family 47, member 1 (SLC47A1) antibody
  • solute carrier family 47 (multidrug and toxin extrusion), member 1 (slc47a1) antibody
  • solute carrier family 47 member 1 (SLC47A1) antibody
  • multidrug and toxin extrusion protein 2-like (LOC100220385) antibody
  • MATE1 (LOC100125995) antibody
  • solute carrier family 47 member 1 (Slc47a1) antibody
  • solute carrier family 47, member 1 (Slc47a1) antibody
  • 1300013J15Rik antibody
  • AI036982 antibody
  • DKFZp469B1821 antibody
  • MATE1 antibody
  • mMATE1 antibody
  • RGD1311123 antibody
  • SLC47A1 antibody
  • zgc:113362 antibody

Protein level used designations for SLC47A1

solute carrier family 47, member 1 , multidrug and toxin extrusion protein 1 , MATE-1 , solute carrier family 47 member 1 , hMATE-1 , multidrug and toxin extrusion 1 , H+/organic cation antiporter variant 1 , H+/organic cation antiporter variant 2 , rMATE-1 , mMATE-1

GENE ID SPECIES
489529 Canis lupus familiaris
541497 Danio rerio
616474 Bos taurus
741988 Pan troglodytes
100171505 Pongo abelii
100220385 Taeniopygia guttata
100125995 Oryctolagus cuniculus
55244 Homo sapiens
360539 Rattus norvegicus
67473 Mus musculus
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