anti-Spindlin 1 (SPIN1) Antibodies

May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).. Additionally we are shipping Spindlin 1 Proteins (9) and Spindlin 1 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SPIN1 10927 Q9Y657
SPIN1 20729 Q61142
SPIN1 361217 Q4V8J7
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Top anti-Spindlin 1 Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SPIN1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human brain WB Suggested Anti-SPIN1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa cells, using SPIN1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Chicken Rabbit Un-conjugated IC, IF, IHC, WB   200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using Spindlin-1 Polyclonal Antibody. 100 μL Log in to see Available
$363.46
Details
Human Rabbit Un-conjugated IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using SPIN1 antibody (ABIN5973464) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat brain using SPIN1 antibody (ABIN5973464) at dilution of 1/100 (40x lens). 100 μL Log in to see 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB ABIN6274560 staining HeLa cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. Western blot analysis of extracts from HeLa cells, using SPIN1 antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using SPIN1 antibody. Immunohistochemistry of paraffin-embedded rat brain using SPIN1 antibody. 200 μL Log in to see 12 to 14 Days
$438.90
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL Log in to see 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti Spindlin 1 Polyclonal Antibody, Unconjugated (ABIN672351) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$317.90
Details

More Antibodies against Spindlin 1 Interaction Partners

Human Spindlin 1 (SPIN1) interaction partners

  1. Data show that spindlin-1 binds methylated arginine R23 of histone H4 (H4), suggsting the function of Spindlin-1.

  2. Results identified a nucleolar localization signal in the N-terminal region of spindlin 1 (SPIN1) that is essential for its enrichment and function in the nucleolus.

  3. identified SPIN.DOC as a transcriptional repressor that binds SPIN1 and masks its ability to engage the H3-Lys-4 trimethylation activation mark

  4. we describe the first example of a histone code reader controlling SkM development in mice, which hints at Spin1 as a potential player in human SkM disease.

  5. miR-489 loss facilitates malignant phenotype of glioma cells probably via SPIN1-mediated PI3K/AKT pathway.

  6. In triple negative breast cancer (TNBC) cells the simultaneous miR-29b-1-5p down regulation and SPIN1 up-regulation can potentially be associated with TNBC malignancy.

  7. These data indicate that miR-489 could reverse the chemoresistance of breast cancer via the PI3K-Akt pathway by targeting SPIN1.

  8. High SPIN1 expression is associated with liposarcoma.

  9. Spindlin1 activates Wnt/beta-catenin signaling downstream from protein arginine methyltransferase 2 (PRMT2) and the MLL complex, which together are capable of generating a specific H3 "K4me3-R8me2a" pattern.

  10. the histone sequence is recognized in a distinct manner involving the amino terminus and a pair of arginine residues of histone H3, and disruption of the binding impaired stimulation of pre-RNA expression by Spindlin1

  11. SPINDLIN1, which may be a novel substrate of the Aurora-A kinase, promotes cancer cell growth through WNT/TCF-4 signaling activation.

  12. Spindlin1 localizes to the active ribosomal DNA (rDNA) repeats, and Spindlin1 facilitates the expression of ribosomal RNA genes.

  13. spindlin1 gene may contribute to tumorigenesis

  14. recombinant human spindlin1 has been overexpressed in Escherichia coli BL21, purified and crystallized using the hanging-drop vapour-diffusion method

  15. analysis of human spindlin1 tudor-like domains for cell cycle regulation

  16. SPINDLIN1 is an important gene for mammalian mitotic chromosome functions, and disrupted regulation results in abnormal cell division, a mechanism that may be involved in tumorigenesis

  17. Excess spindlin1 protein may be detrimental for spindle microtubule organization, chromosomal stability and can potentially contribute to the development of cancer.

Mouse (Murine) Spindlin 1 (SPIN1) interaction partners

  1. Spin1 regulates maternal transcripts post-transcriptionally and is involved in meiotic resumption

  2. Spindlin1 localizes to the active ribosomal DNA (rDNA) repeats, and Spindlin1 facilitates the expression of ribosomal RNA genes.

  3. spindlin1 gene may contribute to tumorigenesis

  4. SPINDLIN1 is an important gene for mammalian mitotic chromosome functions, and disrupted regulation results in abnormal cell division, a mechanism that may be involved in tumorigenesis

  5. Spin1 isoform2 is a protein expressed highly in adult testis, which might be involved in spermatogenesis and could be necessary for normal sperm motility

Pig (Porcine) Spindlin 1 (SPIN1) interaction partners

  1. Spin1 is essential to maintain metaphase II stage arrest, but a high level of Spin1 induces DNA damage in oocytes and embryos.

Spindlin 1 (SPIN1) Antigen Profile

Protein Summary

May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).

Gene names and symbols associated with anti-Spindlin 1 (SPIN1) Antibodies

  • spindlin 1 (SPIN1) antibody
  • spindlin 1 (Spin1) antibody
  • spindlin 1 (spin1) antibody
  • spindlin 1 L homeolog (spin1.L) antibody
  • AA553322 antibody
  • AA673430 antibody
  • DKFZp459K085 antibody
  • MGC115436 antibody
  • spin antibody
  • spindlin antibody
  • Spindlin-1 antibody

Protein level used designations for anti-Spindlin 1 (SPIN1) Antibodies

ovarian cancer-related protein , spindlin-1 , 30000 Mr metaphase complex , SSEC P , spindlin 1

GENE ID SPECIES
10927 Homo sapiens
20729 Mus musculus
361217 Rattus norvegicus
464577 Pan troglodytes
476353 Canis lupus familiaris
541068 Bos taurus
549851 Xenopus (Silurana) tropicalis
734556 Xenopus laevis
100173430 Pongo abelii
100337684 Sus scrofa
100732057 Cavia porcellus
792822 Danio rerio
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