Spindlin 1 Proteins (SPIN1)

May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).. Additionally we are shipping Spindlin 1 Antibodies (42) and Spindlin 1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SPIN1 10927 Q9Y657
SPIN1 20729 Q61142
SPIN1 361217 Q4V8J7
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Top Spindlin 1 Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$953.85
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human SPIN1 Protein. 100 μg Log in to see 11 to 18 Days
$525.90
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,678.50
Details

SPIN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Spindlin 1 (SPIN1) Interaction Partners

Human Spindlin 1 (SPIN1) interaction partners

  1. we describe the first example of a histone code reader controlling SkM development in mice, which hints at Spin1 as a potential player in human SkM disease.

  2. miR (show MLXIP Proteins)-489 loss facilitates malignant phenotype of glioma cells probably via SPIN1-mediated PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) pathway.

  3. In triple negative breast cancer (TNBC) cells the simultaneous miR (show MLXIP Proteins)-29b-1-5p down regulation and SPIN1 up-regulation can potentially be associated with TNBC malignancy.

  4. These data indicate that miR (show MLXIP Proteins)-489 could reverse the chemoresistance of breast cancer via the PI3K (show PIK3CA Proteins)-Akt (show AKT1 Proteins) pathway by targeting SPIN1.

  5. High SPIN1 expression is associated with liposarcoma.

  6. Spindlin1 activates Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling downstream from protein arginine methyltransferase 2 (PRMT2 (show PRMT2 Proteins)) and the MLL (show MLL Proteins) complex, which together are capable of generating a specific H3 "K4me3-R8me2a" pattern.

  7. the histone sequence is recognized in a distinct manner involving the amino terminus and a pair of arginine residues of histone H3 (show HIST3H3 Proteins), and disruption of the binding impaired stimulation of pre-RNA expression by Spindlin1

  8. SPINDLIN1, which may be a novel substrate of the Aurora-A kinase (show AURKA Proteins), promotes cancer cell growth through WNT (show WNT2 Proteins)/TCF-4 (show TCF4 Proteins) signaling activation.

Mouse (Murine) Spindlin 1 (SPIN1) interaction partners

  1. Spin1 regulates maternal transcripts post-transcriptionally and is involved in meiotic resumption

  2. Spin1 isoform2 is a protein expressed highly in adult testis, which might be involved in spermatogenesis and could be necessary for normal sperm motility

Pig (Porcine) Spindlin 1 (SPIN1) interaction partners

  1. Spin1 is essential to maintain metaphase II stage arrest, but a high level of Spin1 induces DNA damage in oocytes and embryos.

Spindlin 1 (SPIN1) Protein Profile

Protein Summary

May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).

Gene names and symbols associated with Spindlin 1 Proteins (SPIN1)

  • spindlin 1 (SPIN1)
  • spindlin 1 (Spin1)
  • spindlin 1 (spin1)
  • spindlin 1 L homeolog (spin1.L)
  • AA553322 protein
  • AA673430 protein
  • DKFZp459K085 protein
  • MGC115436 protein
  • spin protein
  • spindlin protein
  • Spindlin-1 protein

Protein level used designations for Spindlin 1 Proteins (SPIN1)

ovarian cancer-related protein , spindlin-1 , 30000 Mr metaphase complex , SSEC P , spindlin 1

GENE ID SPECIES
10927 Homo sapiens
20729 Mus musculus
361217 Rattus norvegicus
464577 Pan troglodytes
476353 Canis lupus familiaris
541068 Bos taurus
549851 Xenopus (Silurana) tropicalis
734556 Xenopus laevis
100173430 Pongo abelii
100337684 Sus scrofa
100732057 Cavia porcellus
792822 Danio rerio
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