Sterol O-Acyltransferase 1 Proteins (SOAT1)

The protein encoded by SOAT1 belongs to the acyltransferase family. Additionally we are shipping SOAT1 Antibodies (25) and SOAT1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SOAT1 6646 P35610
SOAT1 20652 Q61263
Rat SOAT1 SOAT1 81782 O70536
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Top SOAT1 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,355.45
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

SOAT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Sterol O-Acyltransferase 1 (SOAT1) Interaction Partners

Human Sterol O-Acyltransferase 1 (SOAT1) interaction partners

  1. Soat-1 role in atherosclerosis

  2. Several residues in one subunit closely interact with the same residues in the other subunit; mutating these res. to Cys (show DNAJC5 Proteins) does not lead to loss in enzyme activity. Mutating residues F453, A457, or H460 to Cys (show DNAJC5 Proteins) causes large loss in enzyme activity.

  3. increase in the in vitro ACAT1 (show ACAT1 Proteins) activity in PC-3 (show PCSK1 Proteins) prostate cancer cells treated with androgen

  4. The results suggest that rs1044925 polymorphism in ACAT1 (show ACAT1 Proteins) gene is not only associated with serum LDL-C and nHDLC levels in healthy Chinese subjects in Chengdu area, but also with HDL (show HSD11B1 Proteins)-C level in subjects with endogenous hypertriglyceridemia.

  5. RNA secondary structures located in the vicinity of the GGC (show GGCT Proteins)(1274-1276) codon are required for production of the 56-kDa isoform.

  6. ACAT inhibition may stimulate cholesterol-catabolic (cytochrome P450) pathway in lesion-macrophages.

  7. Angiotensin II enhances foam cell formation by upregulating ACAT1 (show ACAT1 Proteins) expression predominantly through the actions of AT(1) receptor via the G protein/c-Src (show SRC Proteins)/PKC (show PRRT2 Proteins)/MAPK (show MAPK1 Proteins) pathway in human monocyte-macrophages

  8. Docosahexaenoic acid can act as a substrate for ACAT1 (show ACAT1 Proteins). In the manner of a poor substrate, docosahexaenoic acid also inhibited the activity of ACAT1 (show ACAT1 Proteins).

  9. Results suggest that the ERK (show EPHB2 Proteins), p38MAPK (show MAPK14 Proteins) and JNK (show MAPK8 Proteins) signaling pathways may be involved in insulin (show INS Proteins)-mediated regulation of ACAT1 (show ACAT1 Proteins), but no PI3K (show PIK3CA Proteins) and PLC (show HSPG2 Proteins)-gamma signaling pathways were involved in the present study.

  10. Leptin (show LEP Proteins) accelerates cholesteryl ester accumulation in human monocyte-derived macrophages by increasing ACAT-1 (show ACAT1 Proteins) expression.

Mouse (Murine) Sterol O-Acyltransferase 1 (SOAT1) interaction partners

  1. Soat-1 role in atherosclerosis

  2. SOAT1 plays an important role in hypothalamic insulin (show INS Proteins) sensitivity, linked to cognitive impairment, in high fat diet-fed mice.

  3. a potential regulatory relationship between the sterol O-acetyltransferase 1 gene and Hoxc13 gene

  4. Soat1 is a quantitative trait loci gene contributing to hyperlipidemia.

  5. soat1 had an important role in normal hair formation

  6. ACAT1 activity plays a central role in the proper trafficking of cholesterol and in cholesterol-sensing in the macrophage.

SOAT1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with SOAT1

  • sterol O-acyltransferase 1 S homeolog (soat1.S)
  • sterol O-acyltransferase 1 (SOAT1)
  • sterol O-acyltransferase 1 (soat1)
  • sterol O-acyltransferase 1 (CpipJ_CPIJ019799)
  • sterol O-acyltransferase 1 (PTRG_01998)
  • sterol O-acyltransferase 1 (PTRG_00080)
  • sterol O-acyltransferase 1 (Smp_134390)
  • sterol O-acyltransferase (CNF01130)
  • sterol O-acyltransferase (CC1G_00886)
  • sterol O-acyltransferase 1 (Soat1)
  • 8430426K15Rik protein
  • Acact protein
  • Acat protein
  • Acat-1 protein
  • ACAT1 protein
  • ald protein
  • AW550831 protein
  • hid protein
  • si:dkey-21p1.4 protein
  • SOAT protein
  • STAT protein

Protein level used designations for SOAT1

sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 , sterol O-acyltransferase 1 , sterol O-acyltransferase 1-like , sterol O-acyltransferase , acyl-coenzyme A:cholesterol acyltransferase 1 , acyl coenzyme A:cholesterol acyltransferase 1 , adrenocortical lipid depletion , cholesterol acyltransferase 1 , acyltransferase wax synthase , Acyl-coenzyme A:cholesterol acyltransferase 1 , Cholesterol acyltransferase 1

GENE ID SPECIES
446863 Xenopus laevis
457553 Pan troglodytes
564424 Danio rerio
6054215 Culex quinquefasciatus
6339839 Pyrenophora tritici-repentis Pt-1C-BFP
6339947 Pyrenophora tritici-repentis Pt-1C-BFP
8345136 Schistosoma mansoni
100022219 Monodelphis domestica
100145286 Xenopus (Silurana) tropicalis
100436698 Pongo abelii
3258377 Cryptococcus neoformans var. neoformans JEC21
6007810 Coprinopsis cinerea okayama7130
6646 Homo sapiens
20652 Mus musculus
81782 Rattus norvegicus
424424 Gallus gallus
490325 Canis lupus familiaris
100628166 Sus scrofa
504287 Bos taurus
100689317 Cricetulus griseus
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