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STRIP1 encodes a member of the striatin-interacting phosphatase and kinase complex, which is involved in localization of the Golgi body.
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STRIP1 is required for mesenchymal cell migration and is enriched in cellular protrusions in mesenchymal migrating cells.
this study propose that the STRIPAK complex, FAM40A, FAM40B and STRN3, regulates the mode of cancer cell migration by controlling the activity of MST3 and 4, which locally coordinate the phosphorylation of ERM proteins and inhibit the dephosphorylation of MLC leading to increased actin-membrane linkage.
This gene encodes a member of the striatin-interacting phosphatase and kinase complex, which is involved in localization of the Golgi body. The encoded protein participates in cytosketelal organization. Alternative splicing results in multiple transcript variants.
, striatin-interacting protein 1
, FAR11 factor arrest 11 homolog A
, family with sequence similarity 40, member A
, homolog of yeast FAR11 protein 1
, hypothetical protein LOC568805