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Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A\; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.[supplied by OMIM, Nov 2010].. Additionally we are shipping SMC2 Proteins (3) and many more products for this protein.
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Human Polyclonal SMC2 Primary Antibody for ICC, IF - ABIN151837
Canudas, Smith: Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells. in The Journal of cell biology 2009
Show all 6 Pubmed References
Human Polyclonal SMC2 Primary Antibody for WB - ABIN151835
Wood, Liang, Li, Chen: Microcephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair. in The Journal of biological chemistry 2008
SMC2 (or the condensin complex (show SMC4 Antibodies)) is a novel molecular target for the treatment of MYCN (show MYCN Antibodies)-amplified neuroblastoma (show ARHGEF16 Antibodies).
analysis of functional differences of SMC2 and SMC4 hinge domain between condensins and cohesin in DNA recognition
SMC2 gene is altered by both frameshift mutation and loss of expression in gastric and colorectal cancers, suggesting that SMC2 gene alterations might be involved in pathogenesis of these cancers
WNT (show WNT2 Antibodies) signaling can directly activate SMC2 transcription as a key player in the mitotic cell division machinery.
Studies indicate that tagged SMC2 subunit of the condensin complex (show SMC4 Antibodies) with the streptavidin-Binding Peptide (show HP Antibodies) optimising efficacious use of this tag for protein analysis.
human SMC2 hinge domain with short coiled coils was cloned, expressed, purified and crystallized in the orthorhombic space group C222 in native and SeMet-derivatized forms
mutation analysis of hCAP-C (show SMC4 Antibodies) & hCAP-E in leukemia-lymphoma cell lines including 8 pyothorax-associated lymphoma (PAL); 3 of 8 PAL cell lines have hCAP-C (show SMC4 Antibodies) or hCAP-E heterozygous mutations, indicating condensin mutations are relatively frequent in PAL
Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A\; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.
SMC protein 2
, SMC2 (structural maintenance of chromosomes 2, yeast)-like 1
, XCAP-E homolog
, chromosome-associated protein E
, structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E
, structural maintenance of chromosomes protein 2
, FGF-inducible protein 16
, SMC2 structural maintenance of chromosomes 2-like 1
, fibroblast growth factor inducible 16
, chromosome assembly protein XCAP-E
, chromosome scaffold protein ScII