anti-Sucrase-Isomaltase (Alpha-Glucosidase) (SI) Antibodies

SI encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. Additionally we are shipping Sucrase-Isomaltase (Alpha-Glucosidase) Kits (11) and Sucrase-Isomaltase (Alpha-Glucosidase) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SI 69983  
SI 6476 P14410
SI 497756 P23739
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Top anti-Sucrase-Isomaltase (Alpha-Glucosidase) Antibodies at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: SI Sucrase-Isomaltase Antibody [NBP1-87581] - Immunohistochemical staining of human small intestine shows strong luminal membranous and cytoplasmic positivity in glandular cells. Immunohistochemistry-Paraffin: SI Sucrase-Isomaltase Antibody  - Staining of human duodenum shows high expression. 0.1 mL Log in to see 7 to 9 Days
$494.38
Details
Chicken Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 15 to 18 Days
$350.00
Details
Human Rabbit Un-conjugated WB Western Blot: SI Sucrase-Isomaltase Antibody  - Human Small Intestine, concentration 0.2-1 ug/ml. 20 μL Log in to see 8 to 11 Days
$233.06
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged SI is 0.03 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.63 KDa) . 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Rabbit Biotin WB   100 μL Log in to see 11 to 14 Days
$639.83
Details
Human Rabbit FITC WB   100 μL Log in to see 11 to 14 Days
$683.83
Details
Human Rabbit Un-conjugated IF/ICC, IHC, IP, WB Western blot analysis of the recombinant protein. IHC-P analysis of Human Tissue, with DAB staining. 100 μg Log in to see 11 to 18 Days
$440.62
Details

Top referenced anti-Sucrase-Isomaltase (Alpha-Glucosidase) Antibodies

  1. Human Polyclonal SI Primary Antibody for IHC, IHC (p) - ABIN4353435 : Krishnan, Lapierre, Knowles, Goldenring: Rab25 regulates integrin expression in polarized colonic epithelial cells. in Molecular biology of the cell 2013 (PubMed)

More Antibodies against Sucrase-Isomaltase (Alpha-Glucosidase) Interaction Partners

Mouse (Murine) Sucrase-Isomaltase (Alpha-Glucosidase) (SI) interaction partners

  1. Core2 O-glycan structure is essential for expression of SI and DDP-IV during intestinal cell differentiation.

  2. These suggest that induction of SI gene by the diet rich in carbohydrate is associated with acetylation of histone H3 and H4 as well as binding of HNF-1 and Cdx-2 on SI gene.

Human Sucrase-Isomaltase (Alpha-Glucosidase) (SI) interaction partners

  1. Three biosynthetic phenotypes for the novel SI mutations were identified. The first biosynthetic phenotype was defined by mutants that are intracellularly transported in a fashion similar to wild type SI and with normal, but varying, levels of enzymatic activity. The second biosynthetic phenotype was defined by mutants with delayed maturation and trafficking kinetics and reduced activity. The third is inactive.

  2. Novel compound heterozygote V577G/C1531W SI mutations, which lead to lack of SI expression in the duodenal brush border, were found in a family with congenital sucrase-isomaltase deficiency.

  3. A common mutation was found in the sucrase-isomaltase gene, c.273_274delAG, to be responsible for the high prevalence of congenital sucrase-isomaltase deficiency among Inuit people.

  4. SI mutations result in loss of enzyme function by preventing the biosynthesis of catalytically competent SI at the cell surface in lymphocytic leukemia

  5. study found four common mutations in the SI gene (3 of the 4 are in the sucrase domain, with 1 in the isomaltase domain) account for 59 percent of clinical symptoms of congenital sucrase-isomaltase deficiency (CSID); the remaining 41 percent were rare events

  6. investigation of EIS (enzyme-inhibitor-substrate) complex of sucrase: kinetic studies of complex formation/stability; role of complex in prevention of hyperglycemia by L-arabinose

  7. Core2 O-glycan structure is essential for expression of SI and DDP-IV during intestinal cell differentiation.

  8. These results suggest that sucrase-isomaltase transcription might be unchanged or lower in maturity-onset diabetes of the young (MODY) type 3, but greater in MODY5.

  9. phenylalanine cluster is required for shielding a folding determinant in the extracellular domain of SI; substitution of a Q by a P at residue 1098 of sucrase disrupts this determinant and elicits retention of SI(Q1098P) in ER and cis-Golgi

  10. The sucrase-isomaltase (SI) gene from 11 patients of Hungarian origin with congenital sucrase-isomaltase deficiency was analysed.In six out of the 11 patients the phenotype of CSID could be explained by compound heterozygosity.

  11. analysis of a mutation which affects an epitope responsible for the apical targeting fidelity of sucrase-isomaltase in congenital sucrase-isomaltase deficiency

  12. hepatocyte nuclear factor (HNF)-1alpha and HNF-1beta would contribute to constitutive expression of the SI gene in the differentiated state in Caco-2 cells

  13. glucose regulation of sucrase-isomaltase gene expression was attenuated in HNF-1alphaT539fsdelC cells, but was well maintained in empty vector & HNF-1betaR177X cells.Results suggest that HNF-1alpha participates in glucose regulation of SI gene expression.

  14. The effects of mutations in the sucrase domain of SIC1229Y and SIF1745C indicate the importance of a direct interaction between isomaltase and sucrose and the role of sucrose as an intermolecular chaperone in the intracellular transport of SI

Sucrase-Isomaltase (Alpha-Glucosidase) (SI) Antigen Profile

Protein Summary

This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.

Gene names and symbols associated with SI

  • sucrase-isomaltase, intestinal (Tsp_13316) antibody
  • sucrase-isomaltase, intestinal (Tsp_01057) antibody
  • sucrase isomaltase (alpha-glucosidase) (Sis) antibody
  • sucrase-isomaltase (SI) antibody
  • sucrase-isomaltase (Si) antibody
  • 2010204N08Rik antibody
  • SI antibody
  • Si-s antibody
  • SUCIMAL antibody

Protein level used designations for SI

sucrase-isomaltase, intestinal , alpha-glucosidase , sucrase isomaltase, structural , sucrase-isomaltase , oligosaccharide alpha-1,6-glucosidase

GENE ID SPECIES
10899408 Trichinella spiralis
10905132 Trichinella spiralis
69983 Mus musculus
6476 Homo sapiens
100009093 Oryctolagus cuniculus
497756 Rattus norvegicus
100623884 Sus scrofa
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