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The protein encoded by SNTG1 is a member of the syntrophin family.
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Human Polyclonal Syntrophin gamma 1 Primary Antibody for ELISA - ABIN250164
Piluso, Mirabella, Ricci, Belsito, Abbondanza, Servidei, Puca, Tonali, Puca, Nigro: Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells. in The Journal of biological chemistry 2000
Brain-specific (show CALY Antibodies) gamma1-syntrophin participates in gamma-enolase (show ENO2 Antibodies) translocation towards the plasma membrane, a pre-requisite for its neurotrophic activity.
suggests a differentiated role of a modified dystrophin (show DMD Antibodies)-associated complex in the central nervous system
Gamma1-Syntrophin is highly expressed in brain and is specifically localized in hippocampal pyramidal neurons, Purkinje neurons in cerebellum, and cortical neurons. gamma2-Syntrophin is expressed in many tissues including skeletal muscle.
The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This gene is specifically expressed in the brain. Transcript variants for this gene have been described, but their full-length nature has not been determined.
syntrophin, gamma 1
, syntrophin 4