TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4) ELISA Kits

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Additionally we are shipping TAF4 Antibodies (22) and TAF4 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TAF4 6874 O00268
TAF4    
TAF4    
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Top TAF4 ELISA Kits at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 9.375 pg/mL 15.625-1000 pg/mL Typical standard curve 96 Tests Log in to see 12 to 14 Days
$630.00
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Human 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Pig
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$707.14
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Guinea Pig
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Rabbit
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Rat
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Monkey
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Sheep
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Chicken
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Dog
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More ELISA Kits for TAF4 Interaction Partners

Fruit Fly (Drosophila melanogaster) TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4) interaction partners

  1. Daat suggest that holo-TFIID comprises a stable core subcomplex containing TAF4, TAF5, TAF6, TAF9, and TAF12 decorated with peripheral subunits TAF1, TAF2, TAF11, and TBP.

Human TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4) interaction partners

  1. Targeted splicing of hTAF4-TAFH coordinates AS of other TFIID subunits, underscoring the role of TAF4 in synchronised changes of Pol II complex composition essential for efficient cellular reprogramming.

  2. Identification of heteromolecular binding sites in transcription factors Sp1 and TAF4 using high-resolution nuclear magnetic resonance spectroscopy has been reported.

  3. Data suggest that many TATA-box-containing promoters contain a TFIIA recognition element (IIARE) that activates transcription by increasing the recruitment of RNA polymerase II, TFIIA (TF2A1/TF2A2 subunits), TAF4, and P300. (TAF4 = TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1; P300 = E1A binding protein p300)

  4. the two Q-domains of Sp1 and four Q-domains of TAF4 were disordered under physiological conditions.

  5. Inactivation of hTAF4-TAFH domain accelerates differentiation of human neural progenitor cells.

  6. TAF4 isoforms generated by the alternative splicing participate in the conversion of the cellular transcriptional programs from the maintenance of stem cell state to differentiation

  7. These interactions are important to the transcriptional activation of these genes by Rta since introducing TAF4 shRNA substantially reduces the ability of Rta to activate these promoters

  8. huntingtin interacts with Sp1 and TAFII130; transcriptional activity of SP1 and TAFII130 disrupted in early Huntingtin's Disease

  9. Data present the crystal structure of a complex formed by the interacting domains from two subunits of the general transcription factor TFIID, the human TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20).

  10. trans-activation of promoters by simian virus 40 small t-antigen may depend on a consensus TATA motif and such promoters recruit the general transcription factor hTAF(II)130/135

  11. TAF4b incorporation into TFIID induces an open conformation at the lobe involved in TFIIA & putative activator interactions, correlating with differential activator-dependent transcription & promoter recognition by 4b/4-IID.

  12. Findings suggest that DNA binding by TAF4/4b-TAF12 facilitates the association of TFIID with the core promoter of a subset of genes.

TAF4 Antigen Profile

Antigen Summary

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and vitamin D3 receptors. In addition, this subunit interacts with the transcription factor CREB, which has a glutamine-rich activation domain, and binds to other proteins containing glutamine-rich regions. Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases.

Gene names and symbols associated with TAF4

  • TBP-associated factor 4 (Taf4) antibody
  • Taf4p (TAF4) antibody
  • TATA-box binding protein associated factor 4 (TAF4) antibody
  • TATA-box binding protein associated factor 4 L homeolog (taf4.L) antibody
  • CG5444 antibody
  • d110 antibody
  • Dmel\\CG5444 antibody
  • dmTAF4 antibody
  • dTAF4 antibody
  • dTAFII110 antibody
  • dTAF[[II]]110 antibody
  • l(3)72Dj antibody
  • p110 antibody
  • SR3-3 antibody
  • SY3-2 TAF110 antibody
  • TAF antibody
  • TAF2C antibody
  • TAF2C1 antibody
  • TAF4 antibody
  • TAF4A antibody
  • taf110 antibody
  • TAFII110 antibody
  • TAFII130 antibody
  • TAFII135 antibody
  • TAF[II]110 antibody
  • TAF[[II]] antibody
  • Taf[[II]]110 antibody
  • TFIID antibody
  • TFIID 110 antibody

Protein level used designations for TAF4

CG5444-PA , CG5444-PB , CG5444-PC , CG5444-PD , CG5444-PE , CG5444-PF , CG5444-PG , CG5444-PH , TATA-associated factor 110 , TBP associated factor 110 , TBP-associated factor , TBP-associated factor 110 , TBP-associated factor 110kD , Taf4-PA , Taf4-PB , Taf4-PC , Taf4-PD , Taf4-PE , Taf4-PF , Taf4-PG , Taf4-PH , lethal(3)72Dj , hypothetical protein , RNA polymerase II TBP-associated factor subunit C , TAF(II)130 , TAF(II)135 , TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135 kD , TAFII-130 , TAFII-135 , TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD , TBP-associated factor 4 , transcription initiation factor TFIID 130 kDa subunit , transcription initiation factor TFIID 135 kD subunit , transcription initiation factor TFIID 135 kDa subunit , transcription initiation factor TFIID subunit 4

GENE ID SPECIES
39765 Drosophila melanogaster
3645198 Candida albicans SC5314
6874 Homo sapiens
100037075 Xenopus laevis
419223 Gallus gallus
477280 Canis lupus familiaris
100626452 Sus scrofa
789854 Bos taurus
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