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TRPV3 product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. Additionally we are shipping Transient Receptor Potential Cation Channel, Subfamily V, Member 3 Proteins (9) and Transient Receptor Potential Cation Channel, Subfamily V, Member 3 Kits (5) and many more products for this protein.
Showing 10 out of 242 products:
Mammalian Monoclonal TRPV3 Primary Antibody for ISt, IHC - ABIN1305034
Huang, Lee, Chung, Park, Yu, Bradshaw, Coulombe, Walker, Caterina: Overexpressed transient receptor potential vanilloid 3 ion channels in skin keratinocytes modulate pain sensitivity via prostaglandin E2. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008
Show all 2 Pubmed References
Data suggest that Thr264 in TRPV3 is key ERK1 (show MAPK3 Antibodies) phosphorylation site mediating EGFR (show EGFR Antibodies)-induced sensitization of TRPV3 to stimulate signaling pathways involved in regulating skin homeostasis. (TRPV3 = transient receptor potential cation channel subfamily V member-3; ERK1 (show MAPK3 Antibodies) = extracellular signal-regulated kinase-1 (show MAPK3 Antibodies); EGFR (show EGFR Antibodies) = epidermal growth factor receptor (show EGFR Antibodies))
This study identified a direct regulatory effect of MBTPS2 (show MBTPS2 Antibodies) on TRPV3 which can partially contribute to the overlapping clinical features of IFAP (show MBTPS2 Antibodies) and Olmsted syndromes under a common signaling pathway.
TRPV3 may contribute to pruritus in burn scars through TSLP (show TSLP Antibodies).
the expression of transient receptor potential vanilloid-1 (TRPV1 (show TRPV1 Antibodies)), transient receptor potential vanilloid-2 (TRPV2 (show TRPV2 Antibodies)) and transient receptor potential vanilloid-3 (TRPV3) channels in native human odontoblasts, was examined.
TRPV3 was highly expressed in the infiltrating eosinophils and mucosal epithelium of the nasal polyps of ECRS, and further that the more severe the refractoriness was after surgery, the higher the TRPV3 expression was in nasal polyps.
Data indicate that the restoration of a single residue that is apparently missing in the use-dependent homologs could largely eliminate the use dependence of heat sensitivity of vanilloid receptor transient receptor potential 3 (TRPV3).
TRPV3 mutants causing Olmsted Syndrome induce impaired cell adhesion and nonfunctional lysosomes
*We describe two cases of Olmsted-like syndrome in a Mongolian family. *The underlying cause was a previously undescribed G573V point mutation in TRPV3.
The results of the present study show that polymorphism of TRPV3 contributed towards symptom severity in FM.
A novel mutation in TRPV3 gene causes atypical familial Olmsted syndrome in a Chinese family.
results demonstrate that carvacrol from plant oregano is a skin sensitizer or allergen; TRPV3 is involved in the initial phase and the sustained phase of pruritus, whereas TRPA1 (show TRPA1 Antibodies) likely contributes to the initial phase.
These results suggest that TRPV4, TRPV3 and TRPM8 proteins, but not their ion channel activities are necessary for the induction of CIPs at 32 degrees C. Identification of proteins that differentially interact with these TRP channels at 37 degrees C and 32 degrees C would help elucidate the underlying mechanisms of CIP induction by hypothermia.
TRPV3 is involved in the development of ear edema caused by arachinonic acid.
It was concluded that TRPV3 is expressed in a discrete subpopulation of vagal afferent neurons and may contribute to vagal afferent signaling either directly or in combination with TRPV1 (show TRPV1 Antibodies).
findings suggest that although TRPV3 agonism induces hypothermia in rodents, it may have a limited potential as a novel pharmacological method for induction of hypothermia
TRPV3 activation led to a decrease in embryonic stem cell proliferation. Cell cycle analysis revealed that TRPV3 activation increased the percentage of cells in G2/M phase.
In vivo evidence of a cooperative role between skin-derived TRPV3 and primary sensory neurons-enriched TRPV1 (show TRPV1 Antibodies) in modulation of moderate and noxious heat temperature sensation.
We found that NA indeed potentiated TRPV3 while inhibited TRPV2 (show TRPV2 Antibodies) and TRPV4 (show TRPV4 Antibodies)
Study illustrates the antiadipogenic role of TRPV3 in the adipocytes.
Investigated the role of TRPV3 to wound healing using a tooth extraction model and found that oral wound closure was delayed in TRPV3KO compared with that in WT. TRPV3 mRNA was up-regulated in wounded tissues, so TRPV3 may contribute to oral wound repair.
This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene.
transient receptor potential cation channel, subfamily V, member 3
, transient receptor potential cation channel subfamily V member 3-like
, transient receptor potential cation channel subfamily V member 3
, vanilloid receptor-like 3
, vanilloid receptor-related osmotically activated channel protein
, TRP ion channel TRPV3
, heat sensitive channel TRPV3