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TOMM70A encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex. Additionally we are shipping Translocase of Outer Mitochondrial Membrane 70 Homolog A (S. Cerevisiae) Antibodies (61) and Translocase of Outer Mitochondrial Membrane 70 Homolog A (S. Cerevisiae) Kits (17) and many more products for this protein.
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Collectively, this study characterizes a novel protein complex, Tom70/Hsp90 (show HSP90 Proteins)/IRF3 (show IRF3 Proteins)/Bax (show BAX Proteins), that is important for Sendai virus-induced apoptosis.
Tom70 acts as a molecular switch that orchestrates hypertrophic stresses and mitochondrial responses to determine pathological cardiac hypertrophy.
Blockade of mitochondrial protein (show COX6B2 Proteins) import triggers the recruitment of PARK2 (show PARK2 Proteins), by PINK1 (show PINK1 Proteins), to the TOMM machinery.
PINK1 (show PINK1 Proteins) is imported into mitochondria by a unique pathway that is independent of the TOM core complex but crucially depends on the import receptor Tom70
The hepatitis C virus NS3/4A protein induced Tom70 expression.
a novel model in which Tom20 (show TOMM20 Proteins) binds Tom70 to facilitate preprotein release from the chaperones by competition
used biophysical tools to study the interaction between the C-terminal domain of Hsp90 (show HSP90 Proteins) (C-Hsp90 (show HSP90 Proteins)), which contains the EEVD motif that binds to TPR domains, and the cytosolic fragment of Tom70
This study revealed a novel finding, that is, human TOM70 is linked with the hepatitis C virus NS3 protein and the apoptotic response.
Tom70 as a critical adaptor linking MAVS (show MAVS Proteins) to TBK1 (show TBK1 Proteins)/IRF3 (show IRF3 Proteins), revealing that mitochondrion is evolutionarily integrated with innate immunity.
results indicate that the Tom70 monomers are the functional form of the receptor, whereas the homodimers appear to be a minor population, and may represent an inactive state
Our findings showed that Tom70 is essential for melatonin-induced protection against post-myocardial infarction injury
S100A2 (show S100A2 Proteins) and S100A6 (show S100A6 Proteins) interact with another TPR (show GRID2 Proteins) protein Tom70 and regulate the Tom70-ligand interaction in vitro
This gene encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex. This protein is involved in the import of mitochondrial precursor proteins.
translocase of outer mitochondrial membrane 70 homolog A
, translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
, mitochondrial import receptor subunit TOM70
, mitochondrial import receptor subunit TOM70-like
, translocase of outer membrane 70
, mitochondrial precursor proteins import receptor
, translocase of outer membrane 70 kDa subunit