Transmembrane Protein 97 Proteins (TMEM97)

TMEM97 is a conserved integral membrane protein that plays a role in controlling cellular cholesterol levels (Bartz et al., 2009 [PubMed 19583955]).[supplied by OMIM, Aug 2009].. Additionally we are shipping TMEM97 Antibodies (29) and TMEM97 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TMEM97 27346 Q5BJF2
Rat TMEM97 TMEM97 303330 Q5U3Y7
TMEM97 69071 Q8VD00
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Top TMEM97 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,355.45
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$7,626.01
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

TMEM97 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Transmembrane Protein 97 (TMEM97) Interaction Partners

Human Transmembrane Protein 97 (TMEM97) interaction partners

  1. we not only confirmed the elevated MAC30 mRNA, but also demonstrated that GC with overexpression of MAC30 resisted to adjuvant platinum-based chemotherapy.

  2. TMEM97 possesses the full suite of molecular properties that define the sigma2 receptor, and Asp29 and Asp56 are essential for ligand recognition

  3. MAC30 could be a useful biomarker of tumor differentiation and outcome of patients with non-small cell lung cancer. Overexpression of MAC30 predicts a worse tumor differentiated stage and prognosis in patients with non-small cell lung cancer receiving adjuvant chemotherapy.

  4. Study generated a series of sigma1R (show SIGMAR1 Proteins) and sigma2R/Tmem97 agonists and antagonists and tested them for efficacy in the mouse spared nerve injury model. Results show robust antineuropathic pain effects of sigma1R (show SIGMAR1 Proteins) and sigma2R/Tmem97 ligands, demonstrate that sigma2R/Tmem97 is a novel neuropathic pain target, and identify sigma2R/Tmem97 agonist UKH-1114 as a lead molecule for further development.

  5. knockdown of TMEM97 also increases levels of residual NPC1 (show NPC1 Proteins) in NPC1 (show NPC1 Proteins)-mutant patient fibroblasts and reduces cholesterol storage in an NPC1 (show NPC1 Proteins)-dependent manner. Our findings propose TMEM97 inhibition as a novel strategy to increase residual NPC1 (show NPC1 Proteins) levels in cells and a potential therapeutic target for Niemann-Pick type C disease (NP-C).

  6. Overexpression of MAC30 is associated with Squamous Cell Carcinomas of the Lung.

  7. High expression of TMEM97 is associated with glioma.

  8. The down-regulation of MAC30 expression efficiently inhibited the proliferation of gastric cancer cells. Furthermore, the mobility of gastric cancer cells was also inhibited by down-regulation of MAC30.

  9. MAC30 may serve as a new molecular marker to predict the lymph node metastasis and prognosis of patients with epithelial ovarian cancer

  10. Overexpression of MAC30 is associated with non-small-cell lung cancer.

Mouse (Murine) Transmembrane Protein 97 (TMEM97) interaction partners

  1. Study generated a series of sigma1R (show SIGMAR1 Proteins) and sigma2R/Tmem97 agonists and antagonists and tested them for efficacy in the mouse spared nerve injury model. Results show robust antineuropathic pain effects of sigma1R (show SIGMAR1 Proteins) and sigma2R/Tmem97 ligands, demonstrate that sigma2R/Tmem97 is a novel neuropathic pain target, and identify sigma2R/Tmem97 agonist UKH-1114 as a lead molecule for further development.

TMEM97 Protein Profile

Protein Summary

TMEM97 is a conserved integral membrane protein that plays a role in controlling cellular cholesterol levels (Bartz et al., 2009

Gene names and symbols associated with TMEM97

  • transmembrane protein 97 (TMEM97)
  • transmembrane protein 97 (tmem97)
  • transmembrane protein 97 (Tmem97)
  • 1810014L12Rik protein
  • AI115531 protein
  • AL022956 protein
  • D11Bhm182e protein
  • MAC30 protein
  • MGC79660 protein
  • RGD1307423 protein

Protein level used designations for TMEM97

transmembrane protein 97 , hypothetical protein LOC569147

GENE ID SPECIES
417670 Gallus gallus
448515 Xenopus (Silurana) tropicalis
569147 Danio rerio
610900 Canis lupus familiaris
27346 Homo sapiens
303330 Rattus norvegicus
511378 Bos taurus
69071 Mus musculus
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