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The protein encoded by TRIM2 is a member of the tripartite motif (TRIM) family. Additionally we are shipping TRIM2 Antibodies (102) and TRIM2 Proteins (3) and many more products for this protein.
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Studies indicate most-studied TRIpartite Motif (TRIM)-NHL proteins TRIM2, TRIM3, TRIM32 and TRIM71, and their mutations have been linked to diseases.
TRIM2 homozygous missense mutation (c.2000A>C; p.D667A) in a patient with peripheral neuropathy and bilateral vocal cord paralysis
The functional role of the C-terminal NHL domain was characterized in TRIM2.
TRIM2 is repressed by miR (show MLXIP ELISA Kits)-9 and -181c, either alone or in combination.
a role for TRIM2 in mediating the p42/p44 MAPK-dependent ubiquitination of Bim in rapid ischemic tolerance.
Trim2 has an important function in the regulation of axon outgrowth during development.
TRIM2 is an ubiquitin ligase and point to a mechanism regulating neurofilament light subunit metabolism through an ubiquitination pathway that, if deregulated, triggers neurodegeneration
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. Its function has not been identified.
E3 ubiquitin-protein ligase TRIM2
, RING finger protein 86
, tripartite motif protein 2
, tripartite motif protein TRIM2
, tripartite motif-containing 2
, tripartite motif-containing protein 2
, Tripartite motif-containing protein 2
, neural activity-related ring finger protein