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The protein encoded by TRIM54 contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. Additionally we are shipping Tripartite Motif Containing 54 Antibodies (98) and Tripartite Motif Containing 54 Proteins (5) and many more products for this protein.
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The study suggested that the porcine MuRF2 and MuRF3 genes are involved in the muscle growth and development.
A novel protein aggregate myopathies and cardiomyopathy resulting from combined homozygous MuRF1 (show TRIM63 ELISA Kits) null mutation and heterozygous MuRF3 missense mutation.
findings suggest that MuRF3 helps stabilize cardiac PPARalpha (show PPARA ELISA Kits) and PPARgamma1 in vivo to support resistance to the development of diabetic cardiomyopathy. MuRF3 also plays an unexpected role in regulating fat storage despite being found only in striated (show NSDHL ELISA Kits) muscle.
Knockdown of both MURF2 and MURF3 severely disrupts the formation of ordered Z- and M-bands, likely by perturbed tubulin (show TUBB ELISA Kits) dynamics
MuRF3 has an essential role in maintaining cardiac integrity and function after acute myocardial infarction and turnover of FHL2 (show FHL2 ELISA Kits) and gamma-filamin (show FLNC ELISA Kits) contributes to this cardioprotective function of MuRF3
muscle RING finger 1 and muscle RING finger 3 as key E3 ubiquitin ligases for the ubiquitin proteasome system-dependent turnover of sarcomeric proteins and reveal a potential basis for myosin storage myopathies
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
RING finger protein 3
, tripartite motif-containing 54
, tripartite motif-containing protein 54
, ring finger protein 30
, muscle-specific RING finger protein 3
, muscle-specific RING-finger protein 3
, muscle-specific RING-finger protein