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TRIM63 encodes a member of the RING zinc finger protein family found in striated muscle and iris. Additionally we are shipping TRIM63 Proteins (6) and TRIM63 Kits (5) and many more products for this protein.
Showing 10 out of 152 products:
Rat (Rattus) Polyclonal TRIM63 Primary Antibody for ELISA, IHC - ABIN250793
Cao, Kim, Lecker: Ubiquitin-protein ligases in muscle wasting. in The international journal of biochemistry & cell biology 2005
Show all 6 Pubmed References
Human Polyclonal TRIM63 Primary Antibody for IHC (p), IHC - ABIN249804
Hepple, Qin, Nakamoto, Goto: Caloric restriction optimizes the proteasome pathway with aging in rat plantaris muscle: implications for sarcopenia. in American journal of physiology. Regulatory, integrative and comparative physiology 2008
Show all 2 Pubmed References
Human Polyclonal TRIM63 Primary Antibody for ELISA, WB - ABIN249810
Willis, Ike, Li, Wang, Glass, Patterson: Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo. in Circulation research 2007
Show all 2 Pubmed References
Human Polyclonal TRIM63 Primary Antibody for IP, WB - ABIN529746
Meinen, Lin, Rüegg, Punga: Fatigue and muscle atrophy in a mouse model of myasthenia gravis is paralleled by loss of sarcolemmal nNOS. in PLoS ONE 2012
Human Polyclonal TRIM63 Primary Antibody for WB - ABIN4890422
Tardif, Klaude, Lundell, Thorell, Rooyackers: Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients. in The American journal of clinical nutrition 2013
Human Polyclonal TRIM63 Primary Antibody for IF (p), IHC (p) - ABIN741750
Lin, Hanson, Betik, Brennan-Speranza, Hayes, Levinger: Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2016
Dexamethasone-induced MuRF1 upregulation was significantly attenuated in C2C12 myotubes by resveratrol in vitro, but this effect on C2C12 myotubes was abrogated by a knockdown of NF-kappaB (show NFKB1 Antibodies), suggesting that the beneficial effect of resveratrol was NF-kappaB (show NFKB1 Antibodies) dependent. Our findings provide novel information about the ability of resveratrol to prevent or treat muscle atrophy induced by CKD.
Iron-induced skeletal muscle atrophy is suggested to involve the E3 ubiquitin ligase (show MUL1 Antibodies) mediated by the reduction of Akt (show AKT1 Antibodies)-FOXO3a (show FOXO3 Antibodies) signaling by oxidative stress.
MAFbx (show FBXO32 Antibodies) mRNA expression was decreased in old mice relative to adult mice, whereas MuRF1 mRNA expression was less affected by ageing
MuRF2 (show TRIM55 Antibodies) regulates PPARgamma1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet.
MuRF1 directly interacts with PPARalpha (show PPARA Antibodies), mono-ubiquitinates it, and targets it for nuclear export to inhibit fatty acid oxidation in a proteasome independent manner.
Increased Expression of MuRF1 Is Associated with Radiation-induced Laryngeal Muscle Atrophy.
MURF1 was upregulated in cancer cachexia mice.
Expression of USP19 (show USP19 Antibodies) correlates with that of MuRF1 and MAFbx/atrogin-1 (show FBXO32 Antibodies) in skeletal muscles
Sunitinib is able to restrain the overactivation of STAT3 (show STAT3 Antibodies) and MuRF-1 pathways, involved in enhanced muscle protein catabolism during cancer cachexia.
provide evidence that high CO2 activates skeletal muscle atrophy via AMPKalpha2 (show PRKAA2 Antibodies)-FoxO3a (show FOXO3 Antibodies)-MuRF1, which is of biological and potentially clinical significance in patients with lung diseases and hypercapnia
this study shows that aspartate suppresses lipopolysaccharide-induced MuRF1 expression in skeletal muscle via activation of Akt (show AKT1 Antibodies) signaling, and inhibition of AMPKa and FOXO1 (show FOXO1 Antibodies) signaling
role of the muscle specific (show EIF3K Antibodies) E3s MuRF-1 and MAFbx (show FBXO32 Antibodies) in skeletal muscle wasting during various pathologies, as well as their regulation by modifiable lifestyle factors, were explored (review)
the involvement of oxidative stress in the atrophy of COPD peripheral muscle cells in vitro, via the FoxO1/MuRF1/atrogin-1 signaling pathway of the ubiquitin/proteasome system
The mitochondrial damage-cGAS-STING-IRF3 (show IRF3 Antibodies) pathway is critically involved in metabolic stress-induced endothelial inflammation.
Altogether, these results suggest a novel function for p63 (show RPE65 Antibodies) as a contributor to muscular atrophic processes via the regulation of multiple genes, including the muscle atrophy gene Trim63.
A novel protein aggregate myopathies and cardiomyopathy resulting from combined homozygous MuRF1 null mutation and heterozygous MuRF3 (show TRIM54 Antibodies) missense mutation.
Vitamin D3 might have an inhibitory effect on the expression of MAFbx (show FBXO32 Antibodies) and MuRF1 in skeletal muscle.
MURF1 expression intended to be increased in the skeletal muscle of patients with malignant disease even before cancer related cachexia weight loss.
TRIM63 gene expression involved in skin hyperpigmentation.
Skeletal muscle atrophy induced by Angiotensin II involves activation of MuRF1 expression.
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.
ring finger protein 29
, tripartite motif-containing protein 55
, muscle-specific RING finger protein 2
, tripartite motif-containing 63
, ring finger protein 30
, muscle specific ring finger protein 1
, E3 ubiquitin-protein ligase TRIM63
, muscle ring finger protein 1
, muscle specific RING finger protein-1
, e3 ubiquitin-protein ligase TRIM63-like
, tripartite motif containing 63
, iris ring finger protein
, muscle specific ring finger protein 2
, muscle-specific RING finger protein 1
, ring finger protein 28
, striated muscle RING zinc finger protein
, tripartite motif-containing protein 63
, tripartite motif protein 63