anti-Trophoblast Protein 1 Antibodies

Paracrine hormone primarily responsible for maternal recognition of pregnancy.

Type
  • 1
    Primary antibodies
Antigen
  • 1
Reactivity
  • 1
Application
  • 1
  • 1
Host
  • 1
Clonality
  • 1
Clone
  • 1
Isotype
  • 1
Format
  • 1
1 Product
Mouse, Monoclonal (10F558), IgM
ReactivityHuman
Application FACS, IHC
Order details Cat. No. ABIN2388640
$669.43
2 mL
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
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Trophoblast Protein 1 (TP-1P8) Antigen Profile

Protein Summary

Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.

Gene names and symbols associated with TP-1P8

  • ovine trophoblast protein-1 p8 (TP-1P8) antibody
  • IFN-tau2 antibody
  • IFNT2 antibody
  • TP-1 antibody
  • TP-1P8 antibody

Protein level used designations for TP-1P8

ovine trophoblast protein-1 p8 , trophoblastin , Antiluteolysin , Interferon tau-2 , Trophoblast protein 1 , Trophoblast antiluteolytic protein

GENE ID SPECIES
100144751 Ovis aries
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