Tryptase beta 2 (Gene/pseudogene) (TPSB2) ELISA Kits

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Additionally we are shipping and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse TPSB2 TPSB2 17229  
Anti-Rat TPSB2 TPSB2 29268 P50343
Anti-Human TPSB2 TPSB2 64499 P20231
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More ELISA Kits for TPSB2 Interaction Partners

Mouse (Murine) Tryptase beta 2 (Gene/pseudogene) (TPSB2) interaction partners

  1. These data indicate that endogenous mMCP6 has scar-suppressing properties after spinal cord injury via indirect cleavage of axon growth-inhibitory scar components and alteration of the gene expression profile of these factors.

  2. Inflammatory Th2 responses can develop independently of MCP-6, whereas MCP-6 plays a key role in the development of airway hyperresponsiveness.

  3. Tryptase (show TPSAB1 ELISA Kits)-beta was capable of inducing pelvic pain and was increased in experimental autoimmune prostatitis.

  4. mast cell tryptase, a serglycin proteoglycan (show SRGN ELISA Kits)-dependent secretory granule protease, has a role in proteolytic histone modification

  5. Trypase can promote atherosclerotic plaque haemorrhage by promoting angiogenesis and regulating the balance of PAI-1 (show SERPINE1 ELISA Kits) and tPA (show PLAT ELISA Kits).

  6. This study demonstrates for the first time that an mast cell-restricted tetramer-forming tryptase (show TPSAB1 ELISA Kits) has a prominent adverse role in experimental chronic obstructive pulmonary disease

  7. this study indicates that mast cells may be a source of TGF-beta (show TGFB1 ELISA Kits) production after cigarette smoke exposure and that in turn TGF-beta (show TGFB1 ELISA Kits) may change the tryptase (show TPSAB1 ELISA Kits) expression in mast cells.

  8. MCP6 actively depletes the local environment of IL-6 (show IL6 ELISA Kits) to maintain tolerance in mice.

  9. MCP-6 (but not MCP-7 (show TPSAB1 ELISA Kits)) is an essential mast cell-restricted mediator in chemically induced colitis and acts upstream of many of the factors implicated in inflammatory bowel disease.

  10. mast cell mMCP-4, -5, and -6 (chymase (show CMA1 ELISA Kits) and tryptase (show TPSAB1 ELISA Kits)) participate in the acute inflammation and remodeling process of viral myocarditis.

Human Tryptase beta 2 (Gene/pseudogene) (TPSB2) interaction partners

  1. These observations indicate that betaII-tryptase (show TPSAB1 ELISA Kits) activity is post-translationally regulated by an allosteric disulfide bond.

  2. Results indicate a key role for heparin in the activation of human betaI- and beta2-tryptase (show TPSAB1 ELISA Kits).

  3. The disease severity and plasma tryptase (show TPSAB1 ELISA Kits) levels were not affected by the number of alpha or beta tryptase (show TPSAB1 ELISA Kits) alleles in mastocytosis patients.

  4. Strong linkage of TPSAB1 (show TPSAB1 ELISA Kits) and TPSB2 and pairing of deficiency alleles with functional alleles in observed haplotypes protect human subjects from "knockout" genomes and indeed from inheritance of fewer than 2 active alleles.

TPSB2 Antigen Profile

Antigen Summary

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

Gene names and symbols associated with TPSB2

  • tryptase beta 2 (Tpsb2) antibody
  • tryptase beta 2 (gene/pseudogene) (TPSB2) antibody
  • AV011504 antibody
  • Mcp-6 antibody
  • Mcp6 antibody
  • Mcpt6 antibody
  • MMCP-6 antibody
  • TPS2 antibody
  • tryptaseB antibody
  • tryptaseC antibody

Protein level used designations for TPSB2

mast cell protease 6 , tryptase beta-2 , tryptase-2 , rMCP-6 , mast cell tryptase beta II , mast cell tryptase beta III

17229 Mus musculus
29268 Rattus norvegicus
64499 Homo sapiens
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