anti-Tubulin Polymerization Promoting Protein (Tppp) Antibodies

May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. Additionally we are shipping Tppp Kits (35) and Tppp Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Tppp 11076 O94811
Tppp 72948 Q7TQD2
Tppp 361466  
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Top anti-Tppp Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Mouse Heart Tissue; Lane2: Mouse Brain Tissue. 100 μg Log in to see 13 to 16 Days
$314.00
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Immunohistochemistry-Paraffin: TPPP/p25 Antibody  - Negative Control showing staining of paraffin embedded Human Cerebellum, with no primary antibody. Immunohistochemistry-Paraffin: TPPP/p25 Antibody  - (2ug/ml) staining of paraffin embedded Human Cerebellum. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Cow Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Goat Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$455.40
Details

Tppp Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,
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Top referenced anti-Tppp Antibodies

  1. Human Polyclonal Tppp Primary Antibody for ELISA, IHC - ABIN4361514 : Acevedo, Li, Soo, Suryadinata, Sarcevic, Valova, Graham, Robinson, Bernard: The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules. in Experimental cell research 2008 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal Tppp Primary Antibody for WB - ABIN2780164 : Tirián, Hlavanda, Oláh, Horváth, Orosz, Szabó, Kovács, Szabad, Ovádi: TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)

More Antibodies against Tppp Interaction Partners

Human Tubulin Polymerization Promoting Protein (Tppp) interaction partners

  1. This study demonstrated that the AAV9-mediated p25 overexpression mouse model, which is a practical model exhibiting neurodegeneration-like pathological and behavioral changes.

  2. The knowledge accumulated so far underlines the key roles of the multifunctional TPPP/p25 in both physiological and diverse pathological processes, consequently its validation as drug target sorely needs a new innovative strategy that is briefly reviewed here.

  3. TPPP may have a role in poor prognosis in hepatocellular carcinoma

  4. the central folded domain of TPPP/p25 following binding to microtubules can drive s homotypic protein-protein interactions leading to bundled microtubules.

  5. Results reveal a link between p25 (show LCN2 Antibodies) and BACE1 (show BACE Antibodies) in Alzheimer disease (AD) brains and suggest that upregulated Cdk5 (show CDK5 Antibodies) activation by p25 (show LCN2 Antibodies) accelerates AD pathogenesis by enhancing BACE1 (show BACE Antibodies) activity via phosphorylation.

  6. Epigenetic changes in TPPP, in combination with experiences of maltreatment, may confer risk for depression in children.

  7. suggest that the zinc as a specific divalent cation could be involved in the fine-tuning of the physiological TPPP/p25 level counteracting both the enrichment and the lack of this protein leading to distinct central nervous system diseases

  8. results suggest that ROCK regulates beta-catenin stability in cells via preventing TPPP1-mediated inhibition of HDAC6 activity, to reduce its acetylation and degradation via phosphorylation by CK1 and GSK3beta

  9. GSK3 promotes the mitochondrial translocation of p53 (show TP53 Antibodies), enabling its interaction with Bcl2 (show BCL2 Antibodies) to allow Bax (show BAX Antibodies) oligomerization and the subsequent release of cytochrome C (show CYCS Antibodies).

  10. dual Rock and Cdk (show CDK4 Antibodies) phosphorylation of Tppp1 inhibits its regulation of the cell cycle to increase cell proliferation

Mouse (Murine) Tubulin Polymerization Promoting Protein (Tppp) interaction partners

  1. The present study provides additional support for roles for TPPP in the etiology of depression following early adversity.

  2. These results support an essential role for TPPP/p25 in oligodendrocyte differentiation likely via rearrangement of the microtubule system during the process elongation prior to the onset of myelination.

  3. LIMK1 phosphorylation of p25 blocks p25 activity, thus promoting microtubule disassembly.

  4. A pathway was discovered by which p25 (show CDK5R1 Antibodies) and cdk5 (show CDK5 Antibodies) increases the amyloidogenic processing of amyloid precursor protein (show APP Antibodies).

Tppp Antigen Profile

Protein Summary

May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.

Gene names and symbols associated with Tppp

  • tubulin polymerization promoting protein (TPPP) antibody
  • tubulin polymerization promoting protein (Tppp) antibody
  • 2900041A09Rik antibody
  • AI849835 antibody
  • p24 antibody
  • p25 antibody
  • p25alpha antibody
  • RGD1310121 antibody
  • TPPP/p25 antibody
  • TPPP1 antibody

Protein level used designations for Tppp

brain-specific protein p25 alpha , 25 kDa brain-specific protein , brain specific protein p25 alpha , glycogen synthase kinase 3 (GSK3) inhibitor p24 , p25-alpha , tubulin polymerization-promoting protein , tubulin polymerization promoting protein p25 alpha

GENE ID SPECIES
420800 Gallus gallus
11076 Homo sapiens
488072 Canis lupus familiaris
100144410 Sus scrofa
280968 Bos taurus
72948 Mus musculus
361466 Rattus norvegicus
100734397 Cavia porcellus
101110090 Ovis aries
100358311 Oryctolagus cuniculus
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