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The protein encoded by TINAGL1 is similar in sequence to tubulointerstitial nephritis antigen, a secreted glycoprotein that is recognized by antibodies in some types of immune-related tubulointerstitial nephritis.
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Double immunofluorescence analysis showed that CTLA-2alpha was co-localized with cathepsin L (show CTSL1 Antibodies), cathepsin C (show CTSC Antibodies), and TINAGL1 in placenta.
TINAGL1 and B3GALNT1 are possible candidates for drug compounds that inhibit their gene expression
Tinagl1 is related to fertility in adult females but is not essential for either fertilization or preimplantation development (show MTA2 Antibodies) in vitro
Data show that endothelial cell lines SVEC but not MB114 cells express low levels of endogenous LCN7 mRNA and that overexpression significantly increased LCN7 mRNA over basal levels in both cell lines.
results suggest that tubulointerstitial nephritis antigen-like 1(Tinagl1) functions during the postimplantation period
Collectively with the putative role of AZ-1 (show AZI1 Antibodies) in the adrenocortical zonation, we propose that AZ-1 (show AZI1 Antibodies) potentially regulates functions of adrenocortical and VSM cells by modulating cell-matrix interactions
In mouse embryos, the expression of both Tinagl1 mRNA and TINAGL1 protein was increased just prior to implantation. During postimplantation, TINAGL1 expression was restricted to extraembryonic regions.
The protein encoded by this gene is similar in sequence to tubulointerstitial nephritis antigen, a secreted glycoprotein that is recognized by antibodies in some types of immune-related tubulointerstitial nephritis. Three transcript variants encoding different isoforms have been found for this gene.
, TIN Ag-related protein
, TINAG-like 1
, androgen-regulated gene 1
, glucocorticoid-inducible protein 5
, lipocalin 7
, oxidized-LDL responsive gene 2
, tubulointerstitial nephritis antigen-like
, tubulointerstitial nephritis antigen-related protein
, adrenocortical zonation factor 1
, androgen-regulated gene 1 protein