Tumor Necrosis Factor, alpha-Induced Protein 8 Proteins (TNFAIP8)

Acts as a negative mediator of apoptosis.

list all proteins Gene Name GeneID UniProt
Human TNFAIP8 TNFAIP8 25816 O95379
Mouse TNFAIP8 TNFAIP8 106869 Q921Z5
Rat TNFAIP8 TNFAIP8 307428  
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Top TNFAIP8 Proteins at antibodies-online.com

Showing 9 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
Escherichia coli (E. coli) Human GST tag Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8) (AA 2-198), (full length) protein (GST tag) 50 μg Log in to see 13 to 16 Days
$242.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$2,451.17
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,480.50
Details
Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
$2,480.50
Details

More Proteins for Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8) Interaction Partners

Human Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8) interaction partners

  1. The indel chr5:118704153:D, located within TNFAIP8, showed an association with plantar fascial disorders at genome-wide significance (p<5x10(-8)) with small effects (odds ratios=0.93 and 1.07 per allele, respectively).

  2. TNFAIP8 v2 may contribute to both carcinogenesis and chemotherapeutic resistance by broadly suppressing p53 (show TP53 Proteins) activity, thus offsetting p53 (show TP53 Proteins)-dependent tumor suppression.

  3. TNFAIP8 seems to regulate the cell survival and cancer progression processes in a multifaceted manner. (Review)

  4. induction of TNFAIP8 is critical for the evasion of apoptosis by tumor cells expressing the K120R variant of p53 (show TP53 Proteins).

  5. Of these, three CpG sites on TNFAIP8 and PON1 (show PON1 Proteins) genes (corresponding to: cg23917399; cg07086380; and cg07404485, respectively) were significantly differentially methylated between black and non-black individuals. The three CpG sites showed lower methylation status among infants of black women.

  6. TNFAIP8 regulates Hippo (MST1/2) signaling through its interaction with LATS1.

  7. TNFAIP8 overexpression is correlated with axillary lymph node metastasis and poor prognosis in invasive ductal breast carcinoma.

  8. that MicroRNA-9-TNFAIP8 might represent a promising diagnostic biomarker for gastric cancer patients and could be a potential therapeutic target in the prevention and treatment of gastric cancer

  9. these findings suggest that TNFAIP8 overexpression is a potential biomarker to identify pN0 esophageal squamous cell carcinoma patients at higher risk of lymphatic recurrence who may benefit from adjuvant therapy.

  10. Expression of TNFAIP8 is up-regulated in human gastric cancer and regulates cell proliferation, invasion and migration.

Mouse (Murine) Tumor Necrosis Factor, alpha-Induced Protein 8 (TNFAIP8) interaction partners

  1. CD4 (show CD4 Proteins)+ T lymphocyte proliferative activity was significantly down-regulated when TNFAIP8 gene was silenced by siRNA in mice at 24 h post burn. Down-regulation of TNFAIP8 can significantly decrease expression levels of IL-2 (show IL2 Proteins) and soluble IL-2R at 24 h after thermal injury.

  2. TNFAIP8 regulates RAC1 signaling during TNF (show TNF Proteins)-alphaR activation and L. monocytogenes invasion of cells and that this regulation is crucial for controlling cell death and lethal L. mono-cytogenes infection of mice.

  3. Data indicate that mutant Tnfaip8/Oxi-alpha has been crystallized and X-ray data have been collected to 1.8 A using synchrotron radiation.

  4. Tnfaip8 expression is associated with susceptibility to Staphylococcus aureus sepsis.

  5. Data suggest that Galphai-TNFAIP8-mediated rescue of pre-oncogenic cells enhances progression to oncogenic transformation, providing a selective target to inhibit cellular transformation.

  6. Tnfaip8 is crucial in regulating glucocorticoid-mediated apoptosis of thymocytes

TNFAIP8 Protein Profile

Protein Summary

Acts as a negative mediator of apoptosis. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity).

Gene names and symbols associated with TNFAIP8

  • tumor necrosis factor, alpha-induced protein 8-like 1 (tnfaip8l1)
  • TNF alpha induced protein 8 S homeolog (tnfaip8.S)
  • TNF alpha induced protein 8 (TNFAIP8)
  • tumor necrosis factor, alpha-induced protein 8 (Tnfaip8)
  • TNF alpha induced protein 8 (Tnfaip8)
  • AA987150 protein
  • E130304C20Rik protein
  • ENSMUSG00000073567 protein
  • Gg2-1 protein
  • Gm10539 protein
  • MDC-3.13 protein
  • MGC55331 protein
  • Nded protein
  • SCC-S2 protein
  • SCCS2 protein
  • si:dkey-49m19.6 protein
  • Ssc-2 protein
  • zgc:55331 protein

Protein level used designations for TNFAIP8

tumor necrosis factor, alpha-induced protein 8 , TNF alpha-induced protein 8 , tumor necrosis factor alpha-induced protein 8 , NDED , NF-kappa-B-inducible DED-containing protein , TNF-induced protein GG2-1 , head and neck tumor and metastasis-related protein , TNF-induced protein

GENE ID SPECIES
393303 Danio rerio
443963 Xenopus laevis
25816 Homo sapiens
481428 Canis lupus familiaris
100524014 Sus scrofa
106869 Mus musculus
307428 Rattus norvegicus
529336 Bos taurus
427384 Gallus gallus
100171583 Pongo abelii
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