anti-UDP-Glucose Ceramide Glucosyltransferase (UGCG) Antibodies

Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. Additionally we are shipping UGCG Kits (32) and UGCG Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UGCG 7357 Q16739
UGCG 22234 O88693
UGCG 83626 Q9R0E0
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Top anti-UGCG Antibodies at

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-UGCG Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Human Spleen 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB Western blot analysis of UGCG expression in A375 (A), MCF7 (B), Raw264.7 (C), PC12 (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti GCS/glucosylceramide synthase Polyclonal Antibody, Unconjugated (ABIN672096) at 1:200 followed by conjugation to the secondary antibody and DAB staining Mouse splenocytes probed with Rabbit Anti-Ceramide glucosyltransferase Polyclonal Antibody, Unconjugated . 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 15 to 18 Days
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Mouse Skin Tissue. Figure. Western Blot; Sample: Recombinant UGCG, Human. 100 μg Log in to see 15 to 18 Days
Human Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged UGCG is 0.3 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.63 KDa) . 100 μg Log in to see 11 to 12 Days
Human Rabbit Un-conjugated WB UGCG antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB Western Blot: UGCG Antibody [NBP1-62512] - Titration: 0.2-1 ug/ml, Positive Control: Human Spleen. 100 μL Log in to see 8 to 11 Days

Top referenced anti-UGCG Antibodies

  1. Human Monoclonal UGCG Primary Antibody for ELISA, WB - ABIN521242 : Haynes, Filippov, Filippova, Yang, Zhang, Duerksen-Hughes: DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells. in Biochimica et biophysica acta 2012 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal UGCG Primary Antibody for IF (p), IHC (p) - ABIN672096 : Chen, Yin, Cheng, Ding, Gao, Sun, Zhao, Wang, Bao, Xia, Gao, Wang: Effect of D, L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol and tetrandrine on the reversion of multidrug resistance in K562/A02 cells. in Hematology (Amsterdam, Netherlands) 2011 (PubMed)

More Antibodies against UGCG Interaction Partners

Human UDP-Glucose Ceramide Glucosyltransferase (UGCG) interaction partners

  1. Studies show a connection between UDP-glucose ceramide glucosyltransferase (UGCG) and multidrug resistance protein 1 (MDR1 (show ABCB4 Antibodies)) overexpression and multidrug resistance development [Review].

  2. Results suggest that the changes of DNA methylation (show HELLS Antibodies) status of the glucosylceramide synthase (GCS) promoter correlates with multidrug resistance in breast cancer.

  3. Glucosylceramide synthase upregulation is associated with sorafenib resistance in hepatocellular carcinoma.

  4. GCS (show GCLC Antibodies) was upregulated in colorectal carcinoma tissues compared to control tissues.

  5. We found upregulation of specific sphingolipid enzymes, namely sphingomyelin synthase 1 (SMS1 (show SGMS1 Antibodies)), sphingomyelinase 3 (SMPD3), and glucosylceramide synthase (GCS) in the endometrium of endometriotic women.

  6. Our data demonstrates a correlation between the expression of the GCS (show GCLC Antibodies) protein and ER-positive/HER-2 (show ERBB2 Antibodies) negative breast cancer

  7. our work indicates that some UGCG polymorphisms are modifying factors in the severity of GD.

  8. GCS (show GCLC Antibodies) was upregulated in PTCs and might be an independent factor affecting prognosis.

  9. Glucosylceramide synthase mRNA were reduced by 62%.

  10. The results thus show that ARF6 (show ARF6 Antibodies) regulates neuronal differentiation through an effect on glucosylceramide synthase and glucosylceramide levels.

Mouse (Murine) UDP-Glucose Ceramide Glucosyltransferase (UGCG) interaction partners

  1. The cell division gene PCNA (show PCNA Antibodies) was significantly overexpressed in SK2 (show PAPSS2 Antibodies)(-/-) cells, suggesting a cross regulation between sphingosine kinases and Ceramide glucosyltransferase.

  2. we report the development of a novel, orally available glucosylceramide synthase inhibitor (Genz-682452) with pharmacological and safety profiles that have potential for treating Fabry disease.

  3. These results suggest that neuronal glucosylceramide synthase expression modulates mediobasal hypothalamus insulin (show INS Antibodies) signaling and white adipose tissue function in fasted mice.

  4. we measured the expression and activities of Pgp and GCS, UDP-glucose levels, cellular uptake of C12-NBD-ceramide (a fluorescent analogue of ceramide) and ceramide-induced cell death in S and R cells.

  5. Data indicate that verexpression of glucosylceramide synthase in myotubes induces glucosylceramide but enhances insulin (show INS Antibodies) signaling.

  6. Data indicate that mice fed D- threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-PDMP), an inhibitor of glucosylceramide synthase and lactosylceramide synthase showed marked reduction in tumor volume.

  7. The present work demonstrates that hypothalamic integration of metabolic signals requires neuronal expression of glucosylceramide synthase (GCS; UDP-glucose:ceramide glucosyltransferase).

  8. Data indicate that mice with cerebroside sulfotransferases (Cst (show CORT Antibodies)) and UDP-glucose:ceramide glucosyltransferase (Ugcg)/Cst (show CORT Antibodies) deficiency had lower ammonium excretion.

  9. glycosphingolipids in hepatocytes are not essential for sterol, glucose, or lipoprotein metabolism. Ugcg inhibitors exert their effect on hepatocytes either independently of GSL (show CTSA Antibodies) or mediated by other (liver) cell types.

  10. Ugcg and Ugt8a (show UGT8 Antibodies) deficient oligodendroglial did not exhibit any phenotypic or myelin structural abnormalities; abundant and structurally intact myelin can form in their absence

UGCG Antigen Profile

Protein Summary

Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation.

Gene names and symbols associated with UGCG

  • UDP-glucose ceramide glucosyltransferase (UGCG) antibody
  • UDP-glucose ceramide glucosyltransferase S homeolog (ugcg.S) antibody
  • UDP-glucose ceramide glucosyltransferase (ugcg) antibody
  • UDP-glucose ceramide glucosyltransferase (Ugcg) antibody
  • AU043821 antibody
  • C80537 antibody
  • cb539 antibody
  • Epcs21 antibody
  • GCS antibody
  • GlcT-1 antibody
  • GLCT1 antibody
  • sb:cb539 antibody
  • ugcg antibody
  • ugcgb antibody
  • Ugcgl antibody
  • xlcgt antibody
  • zgc:112506 antibody

Protein level used designations for UGCG

ceramide glucosyltransferase , UDP-glucose ceramide glucosyltransferase b , ceramide glucosyltransferase b , ceramide glucosyltransferase-B , GlcT , GLCT-1 , UDP-glucose:N-acylsphingosine D-glucosyltransferase , glucosylceramide synthase , GCS , ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 21 , UDP-glucose:ceramide glycosyltransferase

464660 Pan troglodytes
495444 Xenopus laevis
548887 Xenopus (Silurana) tropicalis
553944 Danio rerio
707875 Macaca mulatta
7357 Homo sapiens
22234 Mus musculus
83626 Rattus norvegicus
514357 Bos taurus
427335 Gallus gallus
481666 Canis lupus familiaris
100152737 Sus scrofa
100730880 Cavia porcellus
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