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Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Additionally we are shipping GALNT7 Antibodies (30) and many more products for this protein.
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miR-494 and GALNT7 play oncogenic roles in nasopharyngeal carcinoma.
High expression of GALNT7 promotes migration and invasion and lymph node metastasis in esophageal squamous cell carcinoma.
GALNT7 and CDK16 (show CDK16 Proteins) were confirmed to be the direct targets of miR (show MLXIP Proteins)-494. These results suggested that miR (show MLXIP Proteins)-494 play an inhibitory role in the tumorigenesis of NPC (show NPC1 Proteins)
The study of miR-34a, miR-34c and its novel target, GALNT7, may serve as novel potential makers for laryngeal squamous cell carcinoma therapy.
miR-214 is a new regulator of GALNT7, and both miR-214 and GALNT7 play important roles in the pathogenesis of cervical cancer
Ectopic expression of miR-30b/30d promoted the metastatic behavior of melanoma cells by directly targeting the GalNAc transferase GALNT7.
MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7
This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation.
, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7
, polypeptide GalNAc transferase 7
, polypeptide N-acetylgalactosaminyltransferase 7
, pp-GaNTase 7
, protein-UDP acetylgalactosaminyltransferase 7